Zobrazeno 1 - 10
of 28
pro vyhledávání: '"C Cromme"'
Autor:
Boris V. Skryabin, C Cromme, Adelheid Korb-Pap, Viktor Wixler, Eugen Retser, Christina Koers-Wunrau, Thomas Pap, Yannis Sotsios, Lars Meyer, Dominique Baeten, Rhonda Bassel-Duby, Katja Mühlenberg, Kurt Redlich, Stephan Ludwig, Neil Smyth, Jessica Bertrand, Paul P. Tak, Birgit Niederreiter
Publikováno v:
Annals of the rheumatic diseases, 74(12), 2216-2223. BMJ Publishing Group
ObjectiveWe analysed the role of the adaptor molecule four-and-a-half Lin11, Isl-1 & Mec-3 (LIM) domain protein 2 (FHL2) in the activation of fibroblast-like synoviocytes in human rheumatoid arthritis (RA) and tumour necrosis factor α (TNFα)-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77920748d82b2d1a6a5ffe16020585c0
https://doi.org/10.1136/annrheumdis-2013-205061
https://doi.org/10.1136/annrheumdis-2013-205061
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 42:1594-1601
Osteoarthritis (OA) is a degenerative joint disease that is characterized primarily by progressive breakdown of articular cartilage. The loss of proteoglycans, the mineralization of the extracellular matrix (ECM) and the hypertrophic differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7a67d9293cfe66cb64333c6cf03624
https://doi.org/10.1016/j.biocel.2010.06.022
https://doi.org/10.1016/j.biocel.2010.06.022
Autor:
Ina Kramer, Michelle Fennen, Denise Beckmann, Athanasios Stratis, Svetlana Frank, Corinna Wehmeyer, Thomas Kamradt, Thomas Pap, U König, Michaela Kneissel, Berno Dankbar, Peter Paruzel, Adelheid Korb-Pap, Annelena Held, Christine Hartmann, C Cromme, Martin Böttcher, Wim B. van den Berg
Publikováno v:
Science Translational Medicine, 8, 330ra35-330ra35
Science Translational Medicine, 8, 330, pp. 330ra35-330ra35
Science Translational Medicine, 8, 330, pp. 330ra35-330ra35
Item does not contain fulltext Sclerostin, an inhibitor of the Wnt/beta-catenin pathway, has anti-anabolic effects on bone formation by negatively regulating osteoblast differentiation. Mutations in the human sclerostin gene (SOST) lead to sclerosteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2cb601ee469ac657bffbaaf1a018f9
http://hdl.handle.net/2066/171465
http://hdl.handle.net/2066/171465
Autor:
Christian Rüter, Julia Scharnert, Sabrina Höfling, Thomas Pap, M. Alexander Schmidt, Jessica Bertrand, C Cromme
Publikováno v:
Virulence. 5(7)
The effector protein Yersinia outer protein M (YopM) of Yersinia enterocolitica has previously been identified and characterized as the first bacterial cell-penetrating protein (CPP). We found that recombinant YopM (rYopM) enters different eukaryotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ecc474d733fd1a25c0f75415b1571e
https://pubmed.ncbi.nlm.nih.gov/25513777
https://pubmed.ncbi.nlm.nih.gov/25513777
Autor:
Denise Beckmann, U König, Peter Paruzel, C Cromme, Annelena Held, Adelheid Korb-Pap, Ina Kramer, Martin Böttcher, Michelle Fennen, Thomas Pap, Michaela Kneissel, Christine Hartmann, W.B. van den Berg, Corinna Wehmeyer, Svetlana Frank, Athanasios Stratis, Thomas Kamradt, Berno Dankbar
Publikováno v:
Annals of the Rheumatic Diseases. 75:A78.1-A78
Background and objectives Wnt-inhibitor sclerostin has anti-anabolic effects on bone formation by negatively regulating osteoblast differentiation. Loss of sclerostin expression results in high bone mass and bone strength in patients with sclerosteos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68e28ed0df936269b5a1627498048b2
https://doi.org/10.1136/annrheumdis-2016-209124.186
https://doi.org/10.1136/annrheumdis-2016-209124.186
Autor:
Thomas Pap, Peter Paruzel, Katja Neugebauer, Adelheide Korb, Athanasios Stratis, Jessica Bertrand, George Kollias, L. Godmann, Corinna Wemeyer, C Cromme, Berno Dankbar, Mareike Fröhling, Frank Echtermeyer
Publikováno v:
Arthritis Research & Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea33dc0edb7b8dfa83e5048fe464175
https://doi.org/10.1186/ar3665
https://doi.org/10.1186/ar3665
Publikováno v:
Annals of the Rheumatic Diseases. 70:A32-A33
Introduction Fibroblast-like synoviocytes (FLS) are key players in the pathogenesis of rheumatoid arthritis (RA). During the onset of the disease, they are transformed into an aggressive phenotype that sustains the joint-destructive inflammatory envi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eaad8a9a991ca53f79ed2ee170636a6
https://doi.org/10.1136/ard.2010.149104.20
https://doi.org/10.1136/ard.2010.149104.20
Autor:
Viktor Wixler, Thomas Pap, Lars Meyer, Jessica Bertrand, R Basel-Duby, C Will, E M Schnaeker, George Kollias, Kurt Redlich, C Cromme, K Neugebauer, Birgit Niederreiter, Adelheid Korb, D Beaten, C Wunrau
Publikováno v:
Annals of the Rheumatic Diseases. 69:A19-A20
Four-and-a-half LIM 2 (FHL2) is a mediator of protein interactions involved in cellular processes that are of relevance for the activation of mesenchymal cells. It interacts with integrins, focal adhesion-and mitogen-activated kinases, transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8449f01f05f1c288c9c57c983ae01e
https://doi.org/10.1136/ard.2010.129593k
https://doi.org/10.1136/ard.2010.129593k
Autor:
Uwe Kornak, M. Rupp, Jessica Bertrand, Michael Amling, Alexander Dietrich, Berno Dankbar, Albrecht Schwab, Daniel Umlauf, Richard Stange, Svetlana Frank, Heriburg Hidding, Thomas Pap, C Cromme, M. Steiner, L.O. Lindemann, Robert P. Marshall
Publikováno v:
Annals of the Rheumatic Diseases. 71:66.3-67
Background Directed monocyte migration, cell-cell contacts and fusion to multinucleated cells are necessary events in the process of osteoclast differentiation. Since transient receptor potential canonical channel 1 (TRPC1) has a pivotal role in thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d3cddbf6021013651a9ee87b7d7efe
https://doi.org/10.1136/annrheumdis-2012-eular.1724
https://doi.org/10.1136/annrheumdis-2012-eular.1724
Publikováno v:
Annals of the Rheumatic Diseases. 71:320.3-321
Background The severe bone destruction during rheumatoid arthritis (RA) is mainly mediated by osteoclasts and thus, reducing osteoclast number is a keystep in ameliorating the outcome of the disease. Yersinia strains are secreting a broad number of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6801039218d20979733111452f3a6376
https://doi.org/10.1136/annrheumdis-2012-eular.2490
https://doi.org/10.1136/annrheumdis-2012-eular.2490