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Autor:
S. Kyriacos, Mohamad Mroueh, Louis Cartilier, C. Chebli, P. Amores da Silva, Bernard Bataille, Teresa Nabais, F. Brouillet
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 65:371-378
High-amylose corn starch, that contains 70% of amylose chains and 30% of amylopectin, has been used to obtain substituted amylose (SA) polymers. Tablets have been prepared by direct compression, i.e. dry mixing of drug and SA, followed by compression
Publikováno v:
International Journal of Pharmaceutics. 222:183-189
Substituted amylose polymers are prepared by reacting amylose chains with a suitable substituent such as 1,2-epoxypropanol (glycidol). Substituted amylose polymers are introduced as novel excipients for controlled release of bioactive materials. Sinc
Autor:
C Chebli, Louis Cartilier
Publikováno v:
International Journal of Pharmaceutics. 193:167-173
Substituted amylose (SA) matrix drug tablets prepared by direct compression show sustained drug-release properties. The influence of compression force (CF) and tablet weight (TW) on release properties was studied. CF ranging from 0.5 to 5.0 tons/cm(2
Autor:
C Chebli, Louis Cartilier
Publikováno v:
International Journal of Pharmaceutics. 171:101-110
The properties of a new tablet binding/disintegrating agent, cross-linked cellulose (CLC), were evaluated in comparison with other binding/disintegrating agents widely used in tablet manufacture such as Avicel PH101® and Avicel PH102®, as well as w
Publikováno v:
Journal of Carbohydrate Chemistry. 14:805-817
A simple route to new surfactants with a sugar-based polar head group coupled to a steroidal hydrophobic group is described. These compounds, N-ursocholyl-d-glucosamine and N-dehydrocholyl-d-glucosamine, were obtained in a three stage process by acyl
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 51:1164-1167
The crystal structure determination of the title compound, C 14 H 14 N 2 O 3 , reinvestigated using low temperature X-ray diffraction data, confirms the earlier report. However, the almost planar molecule is observed in a disordered state. Two partia
Publikováno v:
ChemInform. 26
A simple route to new surfactants with a sugar-based polar head group coupled to a steroidal hydrophobic group is described. These compounds, N-ursocholyl-d-glucosamine and N-dehydrocholyl-d-glucosamine, were obtained in a three stage process by acyl
Akademický článek
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