Proteomic and metabolomic profiles of plasma-derived Extracellular Vesicles differentiate melanoma patients from healthy controls

Autor: SM Bollard, J Howard, C Casalou, BS Kelly, K O'Donnell, G Fenn, J O'Reilly, R Milling, M Shields, M Wilson, A Ajaykumar, K Triana, K Wynne, DJ Tobin, PA Kelly, A McCann, SM Potter

Publikováno v: Translational Oncology, Vol 50, Iss , Pp 102152- (2024)

Background: Plasma-derived Extracellular Vesicles (EVs) have been suggested as novel biomarkers in melanoma, due to their ability to reflect the cell of origin and ease of collection. This study aimed to identify novel EV biomarkers that can discrimi

Externí odkaz: https://doaj.org/article/9410ced3e557417bba370bd9b46d0392

488 Effect of UVB irradiation in epidermal melanocyte and melanoma cell differentiation and apoptosis

Autor: C. Casalou, J.M. Mayatra, K. Wakamatsu, D.J. Tobin

Publikováno v: Journal of Investigative Dermatology. 142:S264

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a8a350a496063eaa1dcb812cff1cc8b
https://doi.org/10.1016/j.jid.2022.09.502

Modulating mucins makes melanin

Autor: C. Casalou, Desmond J. Tobin

Publikováno v: British Journal of Dermatology. 186:388-389

The outermost layer of skin, the epidermis has evolved to provide a physical barrier of protection from harmful substances and invasion of pathogens. The skin barrier consists in part of highly glycosylated proteins called mucins and the epithelium.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93abc77cab5efa77608edce91fd8c24b
https://doi.org/10.1111/bjd.20877

Proteomic and metabolomic profiles of plasma-derived Extracellular Vesicles differentiate melanoma patients from healthy controls.

Autor: Bollard SM; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland; School of Medicine, University College Dublin, Dublin 4, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland. Electronic address: stephaniebollard1@gmail.com., Howard J; School of Medicine, University College Dublin, Dublin 4, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland., Casalou C; Charles Institute of Dermatology, University College Dublin, Dublin 4, Ireland., Kelly BS; School of Medicine, University College Dublin, Dublin 4, Ireland., O'Donnell K; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., Fenn G; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., O'Reilly J; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., Milling R; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., Shields M; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., Wilson M; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland., Ajaykumar A; UCD-Clinical Research Centre, University College Dublin, Dublin 4, Ireland., Triana K; UCD-Clinical Research Centre, University College Dublin, Dublin 4, Ireland., Wynne K; Systems Biology Ireland, University College Dublin, Dublin 4, Ireland., Tobin DJ; Charles Institute of Dermatology, University College Dublin, Dublin 4, Ireland., Kelly PA; UCD School of Veterinary Medicine, University College Dublin, Dublin 4, Ireland., McCann A; School of Medicine, University College Dublin, Dublin 4, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland., Potter SM; Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland; School of Medicine, University College Dublin, Dublin 4, Ireland.

Publikováno v: Translational oncology [Transl Oncol] 2024 Dec; Vol. 50, pp. 102152. Date of Electronic Publication: 2024 Oct 13.

Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity.

Autor: Casalou C; Charles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland., Mayatra JM; Charles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland., Tobin DJ; Charles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.; Conway Institute of Biomedical and Biomolecular Science, University College Dublin, D04 V1W8 Dublin, Ireland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 15; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 15.