Zobrazeno 1 - 10
of 1 995
pro vyhledávání: '"C Caldwell"'
Autor:
Christian B. Bergmann, Bruce D. Hammock, Debin Wan, Falk Gogolla, Holly Goetzman, Charles C. Caldwell, Dorothy M. Supp
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Oxylipins modulate the behavior of immune cells in inflammation. Soluble epoxide hydrolase (sEH) converts anti-inflammatory epoxyeicosatrienoic acid (EET) to dihydroxyeicosatrienoic acid (DHET). An sEH-inhibitor, TPPU, has been demonstrated
Externí odkaz:
https://doaj.org/article/6300e06abb654c439c3679971309bcfc
Autor:
Alexandria C. Caldwell, Christi A. Madden, David M. Thompson, M. Connor Garbe, James R. Roberts, Robert M. Jacobson, Paul M. Darden
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 4, Pp 1059-1067 (2021)
This study explored the association between provider recommendation and adolescent vaccine coverage. We analyzed data from the 2008 to 2018 National Immunization Survey-Teen including coverage with one dose of quadrivalent meningococcal conjugate vac
Externí odkaz:
https://doaj.org/article/07e6197849434c1891ec2a6e862746a1
Autor:
Nadine Beckmann, Amanda M. Pugh, Nicholas J. Auteri, Michael J. Edwards, Erich Gulbins, Charles C. Caldwell
Publikováno v:
Cellular Physiology and Biochemistry, Vol 545, Iss 5, Pp 1054-1067 (2020)
Externí odkaz:
https://doaj.org/article/0eafc35215544281b4a3d0f0b417be23
Autor:
Malamo E. Countouris, MD, Arun Jeyabalan, MD, MS, John C. Caldwell, MD, Jenifer E. Lee, MD, Gavin W. Hickey, MD
Publikováno v:
JACC: Case Reports, Vol 2, Iss 1, Pp 125-130 (2020)
A Bosnian woman at 20 weeks’ gestation presented with dyspnea and hypoxia. She was diagnosed with Eisenmenger physiology with severe pulmonary hypertension, ventricular septal defect, and patent ductus arteriosus. Given high maternal mortality, coo
Externí odkaz:
https://doaj.org/article/1c5bd757338a4d5b9f67d05e0e6f3ee3
Autor:
Monty B. Mazer, MD, Isaiah R. Turnbull, MD, PhD, Sydney Miles, BS, Teresa M. Blood, BS, Brooke Sadler, PhD, Annie Hess, MD, Mitchell D. Botney, MD, Robert S. Martin, MD, James P. Bosanquet, MD, David A. Striker, MD, Nitin S. Anand, MD, Michel Morre, DVM, MSc, Charles C. Caldwell, PhD, Scott C. Brakenridge, MD, MSCS, Lyle L. Moldawer, PhD, Jorge A. Di Paola, MD, Richard S. Hotchkiss, MD, Kenneth E. Remy, MD, MHSc, MSCI
Publikováno v:
Critical Care Explorations, Vol 3, Iss 7, p e0500 (2021)
BACKGROUND:. Immunotherapy treatment for coronavirus disease 2019 combined with antiviral therapy and supportive care remains under intense investigation. However, the capacity to distinguish patients who would benefit from immunosuppressive or immun
Externí odkaz:
https://doaj.org/article/1fac6631ade54835940d3bacdc623ba2
Autor:
Monty B. Mazer, MD, Ethan Davitt, , BS, Isaiah R. Turnbull, MD, PhD, Charles C. Caldwell, PhD, Scott C. Brakenridge, MD, Kenneth E. Remy, MD, MHSc, MSCI, Richard S. Hotchkiss, MD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 4, p e0378 (2021)
Objectives:. Corticosteroid therapy has become standard of care therapy for hospitalized patients infected with the severe acute respiratory syndrome coronavirus-2 global pandemic-causing virus. Whereas systemic inflammation is a notably important fe
Externí odkaz:
https://doaj.org/article/42efcbf7cf9849c7bd6b3948ba35d9b8
Autor:
Brent T. Xia, Nadine Beckmann, Leah K. Winer, Amanda M. Pugh, Timothy A. Pritts, Vanessa Nomellini, Erich Gulbins, Charles C. Caldwell
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 3, Pp 565-579 (2019)
Externí odkaz:
https://doaj.org/article/196bbfe791704a12b8a569d4dac041e8
Autor:
Luke A. Yates, Ricardo J. Aramayo, Nilisha Pokhrel, Colleen C. Caldwell, Joshua A. Kaplan, Rajika L. Perera, Maria Spies, Edwin Antony, Xiaodong Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Replication Protein A (RPA) coats single stranded DNA (ssDNA) generated during DNA recombination, replication and repair. Here the authors present a structural model suggesting how RPA’s DNA-binding domains promote cooperative assembly of multiple
Externí odkaz:
https://doaj.org/article/8d342a9ef98841d4b568cbf8c3f546c6
Autor:
Christian B. Bergmann, Nadine Beckmann, Christen E. Salyer, Marc Hanschen, Peter A. Crisologo, Charles C. Caldwell
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In sepsis and trauma, pathogens and injured tissue provoke a systemic inflammatory reaction which can lead to overwhelming inflammation. Concurrent with the innate hyperinflammatory response is adaptive immune suppression that can become chronic. A c
Externí odkaz:
https://doaj.org/article/04432042b4e9420c86c8a2fa6bd8f092
Autor:
Kenneth E. Remy, Monty Mazer, David A. Striker, Ali H. Ellebedy, Andrew H. Walton, Jacqueline Unsinger, Teresa M. Blood, Philip A. Mudd, Daehan J. Yi, Daniel A. Mannion, Dale F. Osborne, R. Scott Martin, Nitin J. Anand, James P. Bosanquet, Jane Blood, Anne M. Drewry, Charles C. Caldwell, Isaiah R. Turnbull, Scott C. Brakenridge, Lyle L. Moldwawer, Richard S. Hotchkiss
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2021)
COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained vira
Externí odkaz:
https://doaj.org/article/e8dd85cce0b24e16aeb05e045c745304