Zobrazeno 1 - 10
of 4 789
pro vyhledávání: '"C Cabot"'
Autor:
Ilya N. Boykov, McLane M. Montgomery, James T. Hagen, Raphael T. Aruleba, Kelsey L. McLaughlin, Hannah S. Coalson, Margaret A. Nelson, Andrea S. Pereyra, Jessica M. Ellis, Tonya N. Zeczycki, Nasreen A. Vohra, Su-Fern Tan, Myles C. Cabot, Kelsey H. Fisher-Wellman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Targeting mitochondrial oxidative phosphorylation (OXPHOS) to treat cancer has been hampered due to serious side-effects potentially arising from the inability to discriminate between non-cancerous and cancerous mitochondria. Herein, compreh
Externí odkaz:
https://doaj.org/article/de226395575a4fb3a7b262bef6cb95d5
Autor:
Samuel H. C. Cabot, Nikku Madhusudhan, Savvas Constantinou, Diana Valencia, Johanna M. Vos, Thomas Masseron, Connor J. Cheverall
Publikováno v:
The Astrophysical Journal Letters, Vol 966, Iss 1, p L10 (2024)
The study of temperate sub-Neptunes is the new frontier in exoplanetary science. A major development in the past year has been the first detection of carbon-bearing molecules in the atmosphere of a temperate sub-Neptune, K2-18 b, a possible Hycean wo
Externí odkaz:
https://doaj.org/article/c5fe09616ba445af927119d038c546af
Autor:
Thomas F Osborne, Zachary P Veigulis, David M Arreola, Ilya Vrublevskiy, Paola Suarez, Catherine Curtin, Evann Schalch, Rachel C Cabot, Angela Gant-Curtis
Publikováno v:
Digital Health, Vol 9 (2023)
Objective In-hospital falls are a significant cause of morbidity and mortality. The Veterans Health Administration (VHA) has designated fall prevention as a major focus area. The objective of this report is to assess the performance of a new sensor-e
Externí odkaz:
https://doaj.org/article/01648761b04649c785674f3c81f70b92
Publikováno v:
The Astrophysical Journal, Vol 956, Iss 2, p 121 (2023)
The nondetection of a coma surrounding 1I/‘Oumuamua, the first discovered interstellar object (ISO), has prompted a variety of hypotheses to explain its nongravitational acceleration. Given that forthcoming surveys are poised to identify analogs of
Externí odkaz:
https://doaj.org/article/85184934a71d4376b6f50de75f92d8d6
Autor:
Aaron Bello-Arufe, Heather A. Knutson, João M. Mendonça, Michael M. Zhang, Samuel H. C. Cabot, Alexander D. Rathcke, Ana Ulla, Shreyas Vissapragada, Lars A. Buchhave
Publikováno v:
The Astronomical Journal, Vol 166, Iss 2, p 69 (2023)
Extremely low-density exoplanets are tantalizing targets for atmospheric characterization because of their promisingly large signals in transmission spectroscopy. We present the first analysis of the atmosphere of the lowest-density gas giant current
Externí odkaz:
https://doaj.org/article/93603824381d4862b400f75a1165f725
Autor:
John M. Brewer, Lily L. Zhao, Debra A. Fischer, Rachael M. Roettenbacher, Gregory W. Henry, Joe Llama, Andrew E. Szymkowiak, Samuel H. C. Cabot, Sam A. Weiss, Chris McCarthy
Publikováno v:
The Astronomical Journal, Vol 166, Iss 2, p 46 (2023)
Thousands of exoplanet detections have been made over the last 25 years using Doppler observations, transit photometry, direct imaging, and astrometry. Each of these methods is sensitive to different ranges of orbital separations and planetary radii
Externí odkaz:
https://doaj.org/article/4812accc16c542229b2fa2c87dcf3f5c
Autor:
Nataliea Lowson, George Zhou, Duncan J. Wright, Chelsea X. Huang, João M. Mendonça, Samuel H. C. Cabot, Christa Pudmenzky, Robert A. Wittenmyer, David W. Latham, Allyson Bieryla, Gilbert A. Esquerdo, Perry Berlind, Michael L. Calkins
Publikováno v:
The Astronomical Journal, Vol 165, Iss 3, p 101 (2023)
Irradiated Jovian atmospheres are complex and dynamic and can undergo temporal variations due to the close proximity of their parent stars. Of the Jovian planets that have been cataloged to date, KELT-9b is the hottest gas giant known, with an equili
Externí odkaz:
https://doaj.org/article/519503488b55463c82b51714d9a9efba
Autor:
Li-Pin Kao, Samy A.F. Morad, Traci S. Davis, Matthew R. MacDougall, Miki Kassai, Noha Abdelmageed, Todd E. Fox, Mark Kester, Thomas P. Loughran, Jr., Jose' L. Abad, Gemma Fabrias, Su-Fern Tan, David J. Feith, David F. Claxton, Sarah Spiegel, Kelsey H. Fisher-Wellman, Myles C. Cabot
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1590-1602 (2019)
The combination of daunorubicin (dnr) and cytarabine (Ara-C) is a cornerstone of treatment for acute myelogenous leukemia (AML); resistance to these drugs is a major cause of treatment failure. Ceramide, a sphingolipid (SL), plays a critical role in
Externí odkaz:
https://doaj.org/article/fd54fe2e27784a42b78f98d42562f8fa
Autor:
Su-Fern Tan, Wendy Dunton, Xin Liu, Todd E. Fox, Samy A.F. Morad, Dhimant Desai, Kenichiro Doi, Mark R. Conaway, Shantu Amin, David F. Claxton, Hong-Gang Wang, Mark Kester, Myles C. Cabot, David J. Feith, Thomas P. Loughran, Jr.
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 6, Pp 1078-1086 (2019)
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. More than half of older AML patients fail to respond to cytotoxic chemotherapy, and most responders relapse with drug-resistant disease. Failure to achieve complete remission c
Externí odkaz:
https://doaj.org/article/a185154e7e4d47c99c08cbdef0bdcbba
Autor:
Margaret AM Nelson, Kelsey L McLaughlin, James T Hagen, Hannah S Coalson, Cameron Schmidt, Miki Kassai, Kimberly A Kew, Joseph M McClung, P Darrell Neufer, Patricia Brophy, Nasreen A Vohra, Darla Liles, Myles C Cabot, Kelsey H Fisher-Wellman
Publikováno v:
eLife, Vol 10 (2021)
Currently there is great interest in targeting mitochondrial oxidative phosphorylation (OXPHOS) in cancer. However, notwithstanding the targeting of mutant dehydrogenases, nearly all hopeful ‘mito-therapeutics’ cannot discriminate cancerous from
Externí odkaz:
https://doaj.org/article/e567853a8a3040149b87851b0c1938d3