Zobrazeno 1 - 10
of 250
pro vyhledávání: '"C C Schwartz"'
Autor:
R D Shamburek, P G Pentchev, L A Zech, J Blanchette-Mackie, E D Carstea, J M VandenBroek, P S Cooper, E B Neufeld, R D Phair, H B Brewer, Jr, R O Brady, C C Schwartz
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2422-2435 (1997)
Niemann-Pick C disease (NP-C) is a rare inborn error of metabolism with hepatic involvement and neurological sequelae that usually manifest in childhood. Although in vitro studies have shown that the lysosomal distribution of LDL-derived cholesterol
Externí odkaz:
https://doaj.org/article/55306360d4814767a73496af294e7219
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 4, Pp 455-466 (1980)
The present study was designed to obtain more definitive information in man on the metabolic pathways to chenodeoxycholic acid and to cholic acid via a pathway not involving an initial 7 alpha-hydroxylation of cholesterol. Four bile fistula patients
Externí odkaz:
https://doaj.org/article/9d67d01192674ca6ade0b69cd4db5c8c
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 2, Pp 183-195 (1986)
Bile acid production has been quantitated in seven subjects by methods that compare the results of two independent approaches, namely, quantitation of cholesterol side-chain oxidation and fecal bile acid excretion. Six hypertriglyceridemic (HT) subje
Externí odkaz:
https://doaj.org/article/68c3c148d1f54d50b38320f1911b1a7d
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 9, Pp 1594-1607 (2004)
Our aim was to identify and quantify the major in vivo pathways of lipoprotein cholesteryl ester transport in humans. Normal (n = 7), bile fistula (n = 5), and familial hypercholesterolemia (FH; n = 1) subjects were studied. Each received isotopic fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e1b13d71fd29d1c7adc6baa7b429dd
https://doi.org/10.1194/jlr.m300511-jlr200
https://doi.org/10.1194/jlr.m300511-jlr200
Autor:
Richard J. Krieg, Edward P. Norkus, C C Schwartz, Nancy B. Kuemmerle, Pablo Saborio, James C.M. Chan
Publikováno v:
Pediatric Nephrology. 14:740-746
Oxidative stress in unilateral ureteral obstruction (UUO) contributes to the development of glomerular and tubulointerstitial lesions. The present study investigated whether oxidized low-density lipoprotein (oLDL) contributes to the pathogenesis of k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137262518e2247aa89cbd804c7a65311
https://doi.org/10.1007/pl00013428
https://doi.org/10.1007/pl00013428
Autor:
J M VandenBroek, L A Zech, Peter G. Pentchev, H B Brewer, R D Phair, C C Schwartz, Robert D. Shamburek, Edward B. Neufeld, Roscoe O. Brady, E D Carstea, P S Cooper, Joan Blanchette-Mackie
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2422-2435 (1997)
Niemann-Pick C disease (NP-C) is a rare inborn error of metabolism with hepatic involvement and neurological sequelae that usually manifest in childhood. Although in vitro studies have shown that the lysosomal distribution of LDL-derived cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c91d0b64bced9d66876f0695794a44
https://doi.org/10.1016/s0022-2275(20)30027-4
https://doi.org/10.1016/s0022-2275(20)30027-4
Autor:
RD Shamburek, C C Schwartz
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 11, Pp 1833-1842 (1993)
Little is known about the mechanisms of: 1) biliary phosphatidylcholine (PC) secretion by the hepatocyte, 2) selectivity for biliary 1-palmitoyl-2-linoleoyl-PC (PLPC) secretion, and 3) exclusion of 1-stearoyl-2-arachidonyl-PC (SAPC) from bile. The ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51029bbb2f78260e4b8c93685abd7b1
https://doi.org/10.1016/s0022-2275(20)35101-4
https://doi.org/10.1016/s0022-2275(20)35101-4
Publikováno v:
Journal of Clinical Investigation. 91:923-938
Our aim was to identify and quantitate cholesterol pools and transport pathways in blood and liver. By studying bile fistula subjects, using several types of isotopic preparations, simultaneous labeling of separate cholesterol pools and sampling all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321efff3d5d1dc4dcf4ebf2f8389f4a1
https://doi.org/10.1172/jci116314
https://doi.org/10.1172/jci116314
Publikováno v:
Journal of Biological Chemistry. 266:18002-18011
1-Palmitoyl-2-linoleoyl phosphatidylcholine (PLPC) labeled in either the choline, glycerol, palmitate, or linoleate component in reconstituted rat high density lipoprotein (rHDL), was administered by vein to rats with bile fistula and taurocholate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887c2054dc794e8e963f65aac5248c92
https://doi.org/10.1016/s0021-9258(18)55229-7
https://doi.org/10.1016/s0021-9258(18)55229-7
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461347590
The cholesterol molecule, like some other lipids, is very weakly soluble in water. It is present in all cells of humans, mainly in membranes and especially in specialized areas of the plasma membrane such as caveolae and rafts. These areas are rich i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f253a28b7b1d01911467306240da81b
https://doi.org/10.1007/978-1-4419-9019-8_14
https://doi.org/10.1007/978-1-4419-9019-8_14
