Zobrazeno 1 - 10
of 16
pro vyhledávání: '"C C, Silliman"'
Publikováno v:
Transfusion medicine (Oxford, England). 24(3)
Microparticles (MPs) are submicron size cell fragments that are released from cells.We hypothesise that MPs increase during red blood cell (RBC) storage and are part of the pro-inflammatory activity, which accumulates in the RBC supernatant.RBC units
Publikováno v:
Vox sanguinis. 102(4)
Plasma and platelet concentrates are disproportionately implicated in transfusion-related acute lung injury (TRALI). Platelet-derived pro-inflammatory mediators, including soluble CD40 ligand (sCD40L), accumulate during storage. We hypothesized that
Autor:
J P, Tung, Y L, Fung, M, Nataatmadja, K I, Colebourne, H M, Esmaeel, K, Wilson, A G, Barnett, P, Wood, C C, Silliman, J F, Fraser
Publikováno v:
Vox sanguinis. 100(2)
Even with the introduction of specific risk-reduction strategies, transfusion-related acute lung injury (TRALI) continues to be a leading cause of transfusion-related morbidity and mortality. Existing small animal models have not yet investigated TRA
Autor:
J L, Johnson, E E, Moore, D A, Partrick, D Y, Tamura, G, Zallen, D J, Elzi, C C, Silliman, D A, Patrick
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 134(10)
Background Inflammatory stimuli rapidly activate mitogen-activated protein kinases (MAPKs) in neutrophils (PMNs). However, their role in cytotoxic function remains unknown. Elucidating the signals involved in release of cytotoxic agents from PMNs may
Publikováno v:
Surgery. 126(2)
Postinjury multiple organ failure (MOF) is the result of a dysregulated systemic inflammatory response in which primed neutrophils (PMNs) are sequestered in tissues, vulnerable to activation through secondary insults. Apoptosis is critical to the nor
Autor:
P J, Leavey, K S, Sellins, G, Thurman, D, Elzi, A, Hiester, C C, Silliman, G, Zerbe, J J, Cohen, D R, Ambruso
Publikováno v:
Blood. 92(11)
We have studied the effects of granulocyte colony-stimulating factor (G-CSF) administration to normal individuals on a variety of functional and biochemical neutrophil characteristics that relate to host defense. G-CSF adversely affected neutrophil (
Publikováno v:
Surgery. 124(2)
Increased expression of pulmonary endothelial intercellular adhesion molecule-1 (ICAM-1) is obligatory to neutrophil adherence culminating in adult respiratory distress syndrome (ARDS). The p38 mitogen-activated protein kinases (MAPKs) have been esta
Publikováno v:
Medical and pediatric oncology. 30(2)
Octreotide is a synthetic somatostatin analogue which has been suggested for use in the management of acute pancreatitis. While studies have looked at octreotide use in the setting of pancreatitis due to chronic alcohol use or trauma, little is known
Publikováno v:
New horizons (Baltimore, Md.). 4(2)
The continuing study of multiple organ failure (MOF) has led to the development of inflammatory models of tissue injury in contrast to earlier infectious models. This change of focus is in response to more recent clinical observations suggesting that
Autor:
C C, Silliman, G M, Haase, J D, Strain, D W, Luckey, M A, Blake, S A, Caldwell, H L, Wilson, L F, Odom, J L, Ater, B S, Greffe
Publikováno v:
Cancer. 74(1)
Abdominal pain in children receiving chemotherapy for cancer presents the clinician with unique problems due to the altered immunity of these patients or to the oncologic setting. The major clinical decisions regarding these patients are to determine