Zobrazeno 1 - 10
of 75
pro vyhledávání: '"C C, Malbon"'
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 3, Pp 403-413 (1989)
Apolipoprotein E (apoE) is synthesized by a wide variety of cells including cells of the monocyte-macrophage lineage. In order to assess the quantitative significance of apoE synthesis in a mature tissue macrophage, apoE synthesis was compared in Kup
Externí odkaz:
https://doaj.org/article/9a4ab78472cb49c8a719413ea36677e2
Autor:
H-Y, Wang, C C, Malbon
Publikováno v:
Acta physiologica (Oxford, England). 204(1)
The phosphoprotein scaffold Dishevelled is an essential component of both Wnt signalling and of the signalsome that constitutes the supermolecular 'punctae' of assembled proteins often observed in fluorescence microscopy. The C-terminal region beyond
Autor:
J D, Port, C C, Malbon
Publikováno v:
Trends in cardiovascular medicine. 3(3)
The heart is a point of convergence for many transmembrane signal transduction pathways and, as such, exemplifies the complexities of sorting out their interactions. In the heart and cardiovascular system, hormone and neurotransmitter signals are pro
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C1729-C1735
The level of Gs alpha activity has been shown to modulate the rate of adipogenesis in mouse embryo fibroblast 3T3-L1 cells (H.-Y. Wang, D. C. Watkins, and C. C. Malbon. Nature Lond. 358: 334-337, 1992). For the current work the role of Gi alpha 2, a
Publikováno v:
American Journal of Physiology-Cell Physiology. 260:C259-C265
Activation of protein kinase C promotes heterologous desensitization of hepatic adenylate cyclase. The basis for this desensitization was explored by use of a strategy with several independent approaches. Although not influencing the amount of forsko
Publikováno v:
Journal of Molecular Endocrinology. 4:71-79
The cDNA encoding bovine opsin was transfected into Chinese hamster ovary (CHO) cells to generate stable clones expressing the rod cell photoreceptor protein. Cells expressing opsin, when incubated in 11-cis retinal and exposed to light, inhibited fo
Autor:
H y, Wang, C C, Malbon
Publikováno v:
The Journal of biological chemistry. 274(45)
G(s)alpha regulates the differentiation of 3T3-L1 mouse embryonic fibroblasts to adipocytes, a process termed adipogenesis. Inducers of adipogenesis lead to a loss of G(s)alpha and derepress differentiation to adipocytes. The broad spectrum tyrosine
Autor:
C C, Malbon, V, Karoor
Publikováno v:
Cellular signalling. 10(8)
Understanding how cells integrate signals from a variety of chemically diverse information-containing molecules into complex, orchestrated responses such as cell proliferation, differentiation and apoptosis is an overarching goal of cell biology. The
Autor:
V, Karoor, C C, Malbon
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Publikováno v:
Molecular pharmacology. 49(6)
The interactions between beta-adrenergic receptor (beta AR) antagonists and the beta(2)AR were studied with the use of photoaffinity labels. A proteolytic map of the receptor was made and confirmed through amino-terminal amino acid sequencing by loca