Zobrazeno 1 - 10
of 16
pro vyhledávání: '"C C, Funder"'
Publikováno v:
The Journal of Pathology. 111:37-42
Autor:
Charles R. Green, I. C. Calder, M. J. Creek, Patrick J. Williams, C. C. Funder, Kathryn N. Ham, John D. Tange
Publikováno v:
Journal of Medicinal Chemistry. 16:499-502
Publikováno v:
BMJ. 1:152-154
5-Aminosalicylic acid given to rats as a single intravenous injection led to necrosis of the proximal convoluted tubules and of the renal papilla. These two lesions developed at the same time and the cortical lesions did not appear to be a consequenc
Publikováno v:
The Medical journal of Australia. 1(8)
Publikováno v:
Journal of anatomy. 117(Pt 3)
Publikováno v:
British medical journal. 1(5905)
Autor:
N.P. Madsen, I. C. Calder, C.A. Crowe, C. R. Green, John D. Tange, Kathryn N. Ham, C. C. Funder
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 7(6)
1. p-Aminophenol, a known nephrotoxin, has been studied as a model for phenacetin-induced renal damage. 2. Respiration, oxidative phosphorylation and ATPase activity were inhibited in mitochondria isolated from the kidneys of treated rats; this could
Autor:
I. C. Calder, C. R. Green, John D. Tange, D.E. Goss, Kathryn N. Ham, C. C. Funder, P. J. Williams
Publikováno v:
Pathology. 8(1)
N-hydroxyphenacetin, a phenacetin metabolite, was fed to rats as a 0.05-0.5% dietary supplement. After 9 months, tumours of the liver were found in 36 of 64 animals. One animal also developed a renal tumour. No tumours were found in control animals.
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 31(3)
Autor:
C. R. Green, R. A. Woods, Kathryn N. Ham, I. C. Calder, C. C. Funder, P. J. Williams, John D. Tange
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 5(5)
The nephrotoxicity of a number of aminophenols, quinols and catechols has been assessed from the extent of necrosis of proximal convoluted tubules produced by intravenous injection in rats, and the toxicity correlated with the oxidation-reduction pot