Zobrazeno 1 - 10
of 27
pro vyhledávání: '"C Bart Rountree"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128159 (2015)
c-Met, a high-affinity receptor for Hepatocyte Growth Factor (HGF), plays a critical role in tumor growth, invasion, and metastasis. Hepatocellular carcinoma (HCC) patients with activated HGF/c-Met signaling have a significantly worse prognosis. Targ
Externí odkaz:
https://doaj.org/article/2febb3bb2e6149af9bc9f01790fa56e9
Autor:
Nirmala Mavila, David James, Sarah Utley, Nguyen Cu, Orly Coblens, Katrina Mak, C Bart Rountree, Michael Kahn, Kasper S Wang
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50401 (2012)
Fibroblast Growth Factor (FGF)-10 promotes the proliferation and survival of murine hepatoblasts during early stages of hepatogenesis through a Wnt-β-catenin dependent pathway. To determine the mechanism by which this occurs, we expanded primary cul
Externí odkaz:
https://doaj.org/article/c4bbb5ac170b44b2a10f86381a0a11d3
Autor:
Kevin F. Staveley-O'Carroll, Xiaoqiang Qi, Mark Kester, Dai Liu, David J. Cole, Qing X. Yang, Diego M. Avella, Timothy K. Cooper, Todd D. Schell, Jussuf T. Kaifi, Don C. Rockey, Ningfei Li, Guangfu Li, C. Bart Rountree, Eric T. Kimchi
Publikováno v:
Journal of Hepatology. 66:75-85
Background & Aims We have established a clinically relevant animal model of hepatocellular cancer (HCC) in immune competent mice to elucidate the complex dialog between host immunity and tumors during HCC initiation and progression. Mechanistic findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677d260cc778c6284689331ba093452f
https://doi.org/10.1016/j.jhep.2016.07.044
https://doi.org/10.1016/j.jhep.2016.07.044
Autor:
Dhimant Desai, Arthur Berg, Shantu Amin, Eric T. Kimchi, Hephzibah Rani S. Tagaram, Guangfu Li, C. Bart Rountree, Dai Liu, Kevin F. Staveley-O'Carroll, Kavitha Gowda
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 9, Iss 2, p 18 (2016)
Pharmaceuticals; Volume 9; Issue 2; Pages: 18
Pharmaceuticals, Vol 9, Iss 2, p 18 (2016)
Pharmaceuticals; Volume 9; Issue 2; Pages: 18
Hepatocellular carcinoma (HCC) is the third most deadly cancer in the world. New treatment strategies are desperately needed due to limited standard therapies. Activation of the Erk, Akt, and STAT3pathways is implicated in the prognosis of HCC. The S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426a18909f9c914b96cc0e7be891985f
https://pubmed.ncbi.nlm.nih.gov/27023566
https://pubmed.ncbi.nlm.nih.gov/27023566
Autor:
Diego M. Avella, Eric T. Kimchi, Guangfu Li, Serene Shereef, Samuel Shao Min Zhang, Kevin F. Staveley-O'Carroll, Qing X. Yang, Arthur Berg, Hephzibah Rani S. Tagaram, Mark Kester, Todd D. Schell, C. Bart Rountree, Luis S. Garcia, Harriet C. Isom, Dai Liu, Xi Lou
Publikováno v:
Hepatology. 55:141-152
The high rate of mortality and frequent incidence of recurrence associated with hepatocellular carcinoma (HCC) reveal the need for new therapeutic approaches. In this report, we evaluated the efficacy of a novel chemo-immunotherapeutic strategy to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3aac8518ea2457c91b750f66156a12
https://doi.org/10.1002/hep.24652
https://doi.org/10.1002/hep.24652
Publikováno v:
ResearcherID
Sadenosylmethionine (SAMe) is the principal biological methyl donor and a key metabolite that regulates hepatocyte growth, differentiation, and death.1 The biosynthesis of SAMe occurs as the first step in methionine catabolism in a reaction catalyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6037bac9037159841d438166a26b2b
https://doi.org/10.1002/hep.22141
https://doi.org/10.1002/hep.22141
Publikováno v:
Stem Cells. 25:2419-2429
Although oval cells are postulated to be adult liver stem cells, a well-defined phenotype of a bipotent liver stem cell remains elusive. The heterogeneity of cells within the oval cell fraction has hindered lineage potential studies. Our goal was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507004f16ca8732609ae6b4348bf22f4
https://doi.org/10.1634/stemcells.2007-0176
https://doi.org/10.1634/stemcells.2007-0176
Autor:
C. Bart Rountree, Xuli Wang, Shundi Ge, Lora Barsky, Judy Zhu, Ignacio Gonzales, Gay M. Crooks
Publikováno v:
Hepatology. 45:1250-1260
Recent reports have provided conflicting conclusions regarding the role for bone marrow (BM)–derived cells in the regeneration of liver. Our aim was to investigate the potential of BM to contribute to liver epithelium using different BM transplant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2368459d13f690bba35b15671a951d70
https://doi.org/10.1002/hep.21600
https://doi.org/10.1002/hep.21600
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0128159 (2015)
PLoS ONE, Vol 10, Iss 5, p e0128159 (2015)
Background c-Met, a high-affinity receptor for Hepatocyte Growth Factor (HGF), plays a critical role in tumor growth, invasion, and metastasis. Hepatocellular carcinoma (HCC) patients with activated HGF/c-Met signaling have a significantly worse prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb7a9f4691a0d97dacc800ab15a4bcf
http://europepmc.org/articles/PMC4441360
http://europepmc.org/articles/PMC4441360
Publikováno v:
Academic Emergency Medicine. 6:339-344
Objective: To assess patients' knowledge of the responsibilities and roles of physician training in the ED. Methods: This was a prospective survey of a convenience sample of 345 adult patients and family members in an academic county ED. Thirty quest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872ff40f4725abf5c219a7fc55f4d36b
https://doi.org/10.1111/j.1553-2712.1999.tb00399.x
https://doi.org/10.1111/j.1553-2712.1999.tb00399.x