Výsledky vyhledávání - "C B Tara Moore"

Akademický článek

Development of allele-specific therapeutic siRNA in Meesmann epithelial corneal dystrophy.

Autor: Haihui Liao, Alan D Irvine, Caroline J Macewen, Kathryn H Weed, Louise Porter, Laura D Corden, A Bethany Gibson, Jonathan E Moore, Frances J D Smith, W H Irwin McLean, C B Tara Moore

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28582 (2011)

Meesmann epithelial corneal dystrophy (MECD) is an inherited eye disorder caused by dominant-negative mutations in either keratins K3 or K12, leading to mechanical fragility of the anterior corneal epithelium, the outermost covering of the eye. Typic

Externí odkaz: https://doaj.org/article/bf12101fdf8e4f47be433563dfc884a4

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Delivery of siRNA to the Eye: Protocol for a Feasibility Study to Assess Novel Delivery System for Topical Delivery of siRNA Therapeutics to the Ocular Surface

Autor: Paulina, Baran-Rachwalska, Suzanne, Saffie-Siebert, C B Tara, Moore

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2282

Drug delivery to the eye remains a real challenge due to the presence of ocular anatomical barriers and physiological protective mechanisms. The lack of effective siRNA delivery mechanism has hampered the real potential of RNAi therapy, but recent li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ea96ab8845a2f5d85a42c19e01f8143
https://pubmed.ncbi.nlm.nih.gov/33928589

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A Review of Personalised Molecular Medicine for the Treatment of Corneal Disorders

Autor: Courtney DG, Thakur A, Nesbit MA, Moore JE, C. B. Tara Moore

The cornea represents an ideal tissue to elucidate the potential of molecular medicine to treat genetic disorders. It is a small,readily accessible tissue that is easy to monitor treat topically, while a number of corneal disorders are well character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::301eb4f0e6212a94fbbe089e5c612d6b
https://zenodo.org/record/47435

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Excimer laser surface ablation - a review

Autor: Anita, Reynolds, Johnny E, Moore, Shehzad A, Naroo, C B Tara, Moore, Sunil, Shah

Publikováno v: Clinicalexperimental ophthalmology. 38(2)

Corneal surface laser ablation procedures for the correction of refractive error have enjoyed a resurgence of interest, especially in patients with a possible increased risk of complications after lamellar surgery. Improvements in the understanding o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::682d9aa9d7e8f488707c84925859697c
https://pubmed.ncbi.nlm.nih.gov/20398106

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