Zobrazeno 1 - 10
of 64
pro vyhledávání: '"C Asselin-Paturel"'
Publikováno v:
Tissue Antigens. 51:242-249
The effect of TGFbeta1 and IL-12 on calcium-independent cytotoxic pathways was investigated. We have previously demonstrated that the regulatory effect of TGFbeta1 and IL-12 on human alloreative CTL activity was associated with regulation of perforin
Autor:
Isabelle Vergnon, Hamid Echchakir, C Asselin-Paturel, Guillaume Dorothée, Dominique Grunenwald, Salem Chouaib, Fathia Mami-Chouaib
Publikováno v:
International Journal of Cancer. 81:205-213
Non-small-cell lung cancers (NSCLC) are often infiltrated by T lymphocytes. It is postulated that the presence of tumor-infiltrating lymphocytes (TIL) reflects a local host immune response against autologous tumors. To identify the nature of NSCLC TI
Autor:
C Asselin-Paturel, N Lassau, J-M Guinebretière, J Zhang, F Gay, F Bex, S Hallez, J Leclere, P Peronneau, F Mami-Chouaib, S Chouaib
Publikováno v:
Gene Therapy. 6:606-615
To elucidate further the potential of a Semliki Forest virus (SFV) vector in vivo for gene therapy, we constructed a vector, SFV-IL12, to transfer murine IL-12 genes into tumors. A single intratumoral injection of established B16 murine melanoma with
Publikováno v:
The Journal of Immunology. 158:136-143
IL-12 is an important cytokine in the control of cell-mediated immunity. We have investigated the functional interaction of IL-12 with TGF-beta1, a cytokine involved in the regulation of growth and differentiation of immunocompetent cells, during hum
Autor:
H, Echchakir, C, Asselin-Paturel, G, Dorothee, I, Vergnon, D, Grunenwald, S, Chouaib, F, Mami-Chouaib
Publikováno v:
International journal of cancer. 81(2)
Non-small-cell lung cancers (NSCLC) are often infiltrated by T lymphocytes. It is postulated that the presence of tumor-infiltrating lymphocytes (TIL) reflects a local host immune response against autologous tumors. To identify the nature of NSCLC TI
Autor:
C, Asselin-Paturel, H, Echchakir, G, Carayol, F, Gay, P, Opolon, D, Grunenwald, S, Chouaib, F, Mami-Chouaib
Publikováno v:
International journal of cancer. 77(1)
For understanding the local immune response in human non-small cell lung cancer (NSCLC), we investigated both Th1 and Th2-type as well as TGF-beta1 cytokine mRNA expression in 10 fresh tumor biopsies, the corresponding tumor and short term TIL cell l
Autor:
Jacky Bernard, Arsène Burny, Françoise Bex, Peter Berglund, Anne Caignard, J Zhang, Jihed Chehimi, C Asselin-Paturel, Salem Chouaib, Peter Liljeström, Fabienne Willems
Publikováno v:
Karolinska Institutet
IL-12 can enhance the development of effective immune responses against tumors as well as against certain infectious agents. It is therefore a potential candidate for therapeutic use in cancer therapy and in the design of vaccines against several inf
Publikováno v:
Human immunology. 51(1)
The expression of Fas Ligand (FasL) on human TCRalpha/beta and TCRgamma/delta CD4 − /CD8 − MHC class II-alloreactive clones and Fas/FasL-mediated cytotoxicity were investigated. These clones mediated a HLA-DR2-restricted cytotoxicity toward E418
Autor:
Anne Caignard, Géraldine Carayol, Zhenzi Cai, C Asselin-Paturel, Maryvonne Guillard, Salem Chouaib
Publikováno v:
Tissue antigens. 48(4 Pt 1)
The expression of Fas antigen at the surface of renal cell carcinoma and the susceptibility to Fas-mediated lysis by a tumor specific CTL clone were investigated. Renal cell carcinoma cell lines expressed Fas antigen and were susceptible to apoptosis
Publikováno v:
Shock. 21:18