Zobrazeno 1 - 5
of 5
pro vyhledávání: '"C Angel, Cooper"'
Publikováno v:
The Open Respiratory Medicine Journal
Introduction: This study was conducted to evaluate the efficacy of tigecycline (TGC) versus levofloxacin (LEV) in hospitalized patients with community-acquired pneumonia (CAP) using pooled data and to perform exploratory analyses of risk factors asso
Autor:
Jeffrey P. Hammel, Paul G. Ambrose, Joan M. Korth-Bradley, Christopher M. Rubino, C. Angel Cooper, Sujata M. Bhavnani, Nathalie Dartois, Alan Forrest
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:1065-1072
Pharmacokinetic and clinical data from tigecycline-treated patients with hospital-acquired pneumonia (HAP) who were enrolled in a phase 3 clinical trial were integrated in order to evaluate pharmacokinetic-pharmacodynamic (PK-PD) relationships for ef
Autor:
Cristina, Tanaseanu, Carlos, Bergallo, Osvaldo, Teglia, Abel, Jasovich, Maria Eugenia, Oliva, Gary, Dukart, Nathalie, Dartois, C Angel, Cooper, Hassan, Gandjini, Rajiv, Mallick, Marius, Zolubas
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 61:329-338
Tigecycline (TGC), a glycylcycline, has expanded activity against Gram-positive and Gram-negative, anaerobic, and atypical bacteria. Two phase 3 studies were conducted. Hospitalized patients with community-acquired pneumonia (CAP) were randomized to
Autor:
Min Ja Kim, Felix Glumcher, Hassan Gandjini, Antonio T. Freire, C. Angel Cooper, Nathalie Dartois, Oleksiy Datsenko, Yin Ching Chuang, Vasyl Melnyk, Oleksandr Dzyublik, Gary Dukart, Robert Maroko, Joan M. Korth-Bradley
Publikováno v:
Diagnostic microbiology and infectious disease. 68(2)
To compare efficacy and safety of a tigecycline regimen with an imipenem/cilastatin regimen in hospital-acquired pneumonia patients, a phase 3, multicenter, randomized, double-blind, study evaluated 945 patients. Coprimary end points were clinical re
Autor:
Nathalie Dartois, Jean Li Yan, Jay Purdy, Sylvie Jouve, Joan M. Korth-Bradley, Ivana Balter, C. Angel Cooper
Publikováno v:
Clinical Therapeutics. 34:496-507.e1
Background Tigecycline, a broad-spectrum antibiotic used for treating serious bacterial infections in adults, may be suitable for pediatric use once an appropriate dosage is determined. Objective The aim of this study was to assess the pharmacokineti