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Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model

Publikováno v: British Journal of Cancer

Trastuzumab (Herceptin) has improved therapy of breast cancer. Only patients overexpressing ERBB2 are treated with trastuzumab, whereas its use in tumours without ERBB2 expression is useless. This led to the concept that the subgroup of trastuzumab-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b966e9f9829b7878f7892b4918ef23
http://europepmc.org/articles/PMC2391101

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Neuroreceptors and ion channels as targets of alcohol

Publikováno v: Alcoholism, clinical and experimental research. 25(5 Suppl)

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Toshio Narahashi and Kinya Kuriyama. The presentations were (1) Modulation of neuroreceptors and ion channels by alcohol, by T. Narah

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6086ecddf048332e30e8a808165bb973
https://pubmed.ncbi.nlm.nih.gov/11391069

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Akademický článek

Common and differential variables of anxiety and depression in adolescence: a nation-wide smartphone-based survey.

Autor: Weiß, Martin^1,2 Weiss_M11@ukw.de, Gutzeit, Julian^1,3, Pryss, Rüdiger^4,5, Romanos, Marcel⁶, Deserno, Lorenz^6,7, Hein, Grit¹

Publikováno v: Child & Adolescent Psychiatry & Mental Health. 8/17/2024, Vol. 18 Issue 1, p1-9. 9p.

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P2Y receptor expression on astrocytes in the nucleus accumbens of rats

Autor: H Franke, U Krügel, J Grosche, C Heine, W Härtig, C Allgaier, P Illes

Publikováno v: Neuroscience. 127(2)

The expression of purinoceptor (P2)Y-subtypes on astrocytes in vivo under physiological conditions and after stab wound injury was investigated. Reverse transcriptase-polymerase chain reaction with specific primers for the receptor-subtypes P2Y1,2,4,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a937f2622319c10380be34c20268513
https://pubmed.ncbi.nlm.nih.gov/15262333

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UTP evokes noradrenaline release from rat sympathetic neurons by activation of protein kinase C

Autor: N, Vartian, E, Moskvina, T, Scholze, U, Unterberger, C, Allgaier, S, Boehm

Publikováno v: Journal of neurochemistry. 77(3)

The pathway involved in UTP-evoked noradrenaline release was investigated in cultures of rat superior cervical ganglia. Northern blots revealed an age-related increase in levels of mRNA for P2Y6 receptors in cultures obtained at postnatal days 1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1bfe51df7f8d16ed35f9a7aaacb4ef0
https://pubmed.ncbi.nlm.nih.gov/11331416

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Akademický článek

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NMDA receptor characterization and subunit expression in rat cultured mesencephalic neurones

Autor: C, Allgaier, P, Scheibler, D, Müller, T J, Feuerstein, P, Illes

Publikováno v: British journal of pharmacology. 126(1)

1. NMDA-induced changes in free intracellular Ca2+ concentration ([Ca2+]i) were determined in individual cultured rat mesencephalic neurones by the fura-2 method. mRNA expression encoding NMDA receptor subunits (NR1, NR2A-D) was examined by RT-PCR. 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94ee7abf439853950451b9d10c588b63
https://pubmed.ncbi.nlm.nih.gov/10051128

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