Zobrazeno 1 - 10
of 76
pro vyhledávání: '"C A Lingwood"'
Autor:
C A Lingwood
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 9, Pp 1010-1012 (1984)
Photoactivatable heterobifunctional crosslinking agents have been used to prepare glycolipid affinity matrices by nitrene insertion into adsorbed ligand. High degrees of covalent coupling have been obtained and the method has been used to purify anti
Externí odkaz:
https://doaj.org/article/6f2047286a2941f49207776caadf73df
Autor:
B. Hall, G. Burt, R. Apsimon, C. J. Lingwood, A. Tutte, A. Grudiev, A. Macpherson, M. Navarro-Tapia, R. Calaga, K. G. Hernández-Chahín, R. B. Appleby, P. Goudket
Publikováno v:
Physical Review Accelerators and Beams, Vol 20, Iss 1, p 012001 (2017)
A 4-rod deflecting structure is proposed as a possible crab cavity design for the LHC high luminosity upgrade. Crab cavities are required for the LHC luminosity upgrade to provide a greater bunch overlap in the presence of a crossing angle, but must
Externí odkaz:
https://doaj.org/article/a33174c707014fcab636f16d2f483129
Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane
Autor:
Cornelia Schroeder, Kai Simons, C A Lingwood, Julio L. Sampaio, Beth Binnington, Lucie Kalvodova, Dirk Lindemann, Severino Urban, Jean-Marc Verbavatz, Mathias J. Gerl, Andrej Shevchenko
Publikováno v:
The Journal of Cell Biology
Analysis of the lipid composition of influenza virus–infected cells provides support for the membrane raft-based biogenesis model.
The influenza virus (IFV) acquires its envelope by budding from host cell plasma membranes. Using quantitative s
The influenza virus (IFV) acquires its envelope by budding from host cell plasma membranes. Using quantitative s
Autor:
Mustafa Kamani, Beth Binnington, Murugesapillai Mylvaganam, C A Lingwood, Brigitte Rigat, Robert Tian
Publikováno v:
Journal of Biological Chemistry. 286:21413-21426
Mammalian glycosphingolipid (GSL) precursor monohexosylceramides are either glucosyl- or galactosylceramide (GlcCer or GalCer). Most GSLs derive from GlcCer. Substitution of the GSL fatty acid with adamantane generates amphipathic mimics of increased
Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 9, Pp 1744-1755 (2009)
Glycosphingolipid (GSL) fatty acid strictly regulates verotoxin 1 (VT1) and the HIV adhesin, gp120 binding to globotriaosyl ceramide within Gb(3)/cholesterol detergent resistant membrane (DRM) vesicle constructs and in Gb(3) water-air interface monol
Autor:
Michał Grzybek, Daniel Lingwood, Tomasz Róg, Ünal Coskun, C A Lingwood, Kai Simons, Ilpo Vattulainen, Beth Binnington
Publikováno v:
Lingwood, D, Binnington, B, Róg, T, Vattulainen, I, Grzybek, M, Coskun, U, Lingwood, C A & Simons, K 2011, ' Cholesterol modulates glycolipid conformation and receptor activity ', Nature Chemical Biology, vol. 7, no. 5, pp. 260-262 . https://doi.org/10.1038/nchembio.551
We document a new dimension of surface recognition in which communication is controlled through the collective behavior of lipids. Membrane cholesterol induces a tilt in glycolipid receptor headgroup, resulting in loss of access for ligand binding. T
Autor:
C. A. Lingwood
Publikováno v:
Trends in Glycoscience and Glycotechnology. 12:7-16
精製されているはずの糖脂質を薄層クロマトグラフィーで調べると、2つとか3つのバンドに分かれてしまうことがよくあるが、組換えキメラタンパク質、遺伝子導入、シグナル伝達、リ
Publikováno v:
The Journal of Cell Biology
The B subunit of verotoxin (VT1B) from enterohemorrhagic Escherichia coli is responsible for the attachment of the holotoxin to the cell surface, by binding to the glycolipid, globotriaosyl ceramide. After receptor-mediated endocytosis, the toxin is
Publikováno v:
Infection and Immunity. 64:1714-1719
In pigs with edema disease, verotoxin 2e (VT2e) is produced in the intestine and transported to tissues, but neither the mechanism by which toxin passes through the intestine nor its failure to induce an enterotoxic reaction is understood. Binding of
Publikováno v:
Infection and Immunity. 63:2766-2769
Escherichia coli O157:H7-related vascular damage such as hemolytic uremic syndrome is believed to require the Shiga-like toxins. This study demonstrated that sodium butyrate sensitized human umbilical vein endothelial cells to Shiga toxin and increas