Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C A Kanawati"'
Autor:
Marwen Ghabra, E. Kondeatis, Robert Vaughan, Philip I. Murray, Neil Modi, Farida Fortune, Louise Bye, Graham R. Wallace, Miles Stanford, C A Kanawati, Eldad Ben-Chetrit
Publikováno v:
Tissue Antigens. 72:49-53
Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is regarded with other molecules such as HLA, PTPN22 and CARD15 as genetic master switches of autoimmunity. Single nucleotide polymorphisms (SNPs) in the genes encoding these molecules have been as
Autor:
David H. Verity, Graham R. Wallace, E Kondeatis, Wafa Madanat, H Zureikat, C. A. Kanawati, J. E. Marr, Robert Vaughan, Faisal Fayyad, Miles Stanford
Publikováno v:
European Journal of Immunogenetics. 27:73-76
Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms have been implicated in the susceptibility to inflammatory diseases, including multiple sclerosis and inflammatory bowel disease. The expression of both soluble and tissue ICAM-1 is increa
Autor:
Miles Stanford, J. E. Marr, G R Wallace, Wafa Madanat, D H Verity, Faisal Fayyad, C A Kanawati, Robert Vaughan, H Zureikat, E. Kondeatis
Publikováno v:
Tissue Antigens. 54:264-272
The role of HLA-B*51 and other major histocompatibility complex (MHC) genes in Behcet's disease (BD) remains unknown. We have performed HLA and tumour necrosis factor (TNF) polymorphism analysis in BD and evaluated their contribution to ocular diseas
Autor:
Philip I. Murray, E. Kondeatis, Robert Vaughan, Marwen Ghabra, Wafa Madanat, Farida Fortune, Vijay Baranathan, Elizabeth M. Graham, G R Wallace, C A Kanawati, Miles Stanford
Objectives - A single nucleotide polymorphism (SNP) of the gene encoding protein tyrosine phosphatase type 22 (PTPN22 620W) has recently been described as a strong common genetic risk factor for human autoimmune disease. We have analysed the associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46df529b26f9e124098d494abd07ffc0
https://europepmc.org/articles/PMC2111602/
https://europepmc.org/articles/PMC2111602/
Autor:
Y. Chen, Miles Stanford, E Kondeatis, Wafa Madanat, Graham R. Wallace, Farida Fortune, Elizabeth M. Graham, Robert Vaughan, C A Kanawati, David H. Verity
Publikováno v:
Human immunology. 68(2)
Behcet's disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulceration, ocular inflammation, and skin lesions. The etiology of the disease is currently unknown but evidence suggests that there is a strong genetic
Autor:
C A Kanawati, G Wallace, S E Marshall, L Zhang, F Gogus, Ali Çelik, Wafa Madanat, Tariq Ahmad, Matt J. Neville, M Stanford, Derek P. Jewell, T James, D Verity, Farida Fortune, F Fayyad
Publikováno v:
Scandinavian journal of rheumatology. 34(3)
BACKGROUND: Behçet's disease (BD) is a chronic multi-system inflammatory disorder of unknown aetiology, which shares many features of the inflammatory bowel diseases (IBDs). CARD15 has recently been identified as the first susceptibility gene in Cro
Autor:
X, Yang, T, Ahmad, F, Gogus, D, Verity, G R, Wallace, W, Madanat, C A, Kanawati, M R, Stanford, F, Fortune, D P, Jewell, S E, Marshall
Publikováno v:
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 31(1)
Summary Chemokines are important determinants of the early inflammatory response. The CC chemokine receptor 5 (CCR5) Δ32 variant results in a non-functional form of the chemokine receptor, and has been implicated in a variety of immune-mediated dise
Autor:
D H, Verity, R W, Vaughan, E, Kondeatis, W, Madanat, H, Zureikat, F, Fayyad, J E, Marr, C A, Kanawati, G R, Wallace, M R, Stanford
Publikováno v:
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 27(2)
Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms have been implicated in the susceptibility to inflammatory diseases, including multiple sclerosis and inflammatory bowel disease. The expression of both soluble and tissue ICAM-1 is increa
Autor:
D H, Verity, G R, Wallace, R W, Vaughan, E, Kondeatis, W, Madanat, H, Zureikat, F, Fayyad, J E, Marr, C A, Kanawati, M R, Stanford
Publikováno v:
Tissue antigens. 54(3)
The role of HLA-B*51 and other major histocompatibility complex (MHC) genes in Behçet's disease (BD) remains unknown. We have performed HLA and tumour necrosis factor (TNF) polymorphism analysis in BD and evaluated their contribution to ocular disea
Autor:
Paul T. Seed, Miles Stanford, J. Holland-Gladwish, David H. Verity, C. A. Kanawati, I. Ayesh, Graham R. Wallace
Publikováno v:
Ocular immunology and inflammation. 6(2)
Behçet's disease (BD) may lead to blindness in up to 25% of eyes. Soluble (s)ICAM-1 but not sVCAM-1 is associated with relapse in idiopathic uveoretinitis and is reported to be raised in BD patients. We have investigated the levels of sICAM-1 and sV