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Autor:
E L, Saenko, N, Ananyeva, D, Kouiavskaia, H, Schwinn, D, Josic, M, Shima, C A E, Hauser, S, Pipe
Publikováno v:
Vox sanguinis. 83(2)
Molecular defects in Factor VIII (FVIII), such as haemophilia A-related mutations or denaturative conformational changes, may affect the stability of FVIII as well as its interactions with physiological activators, von Willebrand Factor, phospholipid