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Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents

Autor: Darell D. Bigner, Henry S. Friedman, Peter J. Houghton, Colvin Om, C B Hare, Stephen T. Keir, Gertrude B. Elion, C A Coggins

Publikováno v: Cancer Chemotherapy and Pharmacology. 41:485-490

Two major obstacles in the treatment of patients with central nervous system malignancies are drug resistance and host toxicity. The goal of combination chemotherapy is to achieve therapeutic effects that are more favorable than using a single drug a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d9fd7fa80af2e11441314ef9867f8d
https://doi.org/10.1007/s002800050771

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Ninety-Day Inhalation Study in Rats, Using Aged and Diluted Sidestream Smoke from a Reference Cigarette: DNA Adducts and Alveolar Macrophage Cytogenetics

Autor: C K, Lee, B G, Brown, E A, Reed, C R, Coggins, D J, Doolittle, A W, Hayes

Publikováno v: Fundamental and Applied Toxicology. 20:393-401

To study the genotoxic effects of subchronic exposure to environmental tobacco smoke, Sprague-Dawley rats were exposed to 0, 0.1, 1.0, and 10 mg total particulate matter (TPM)/m3 of aged and diluted sidestream smoke (ADSS) from 1R4F reference cigaret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a018a933ef8ba8158c2a70f56e1fd2
https://doi.org/10.1006/faat.1993.1051

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A review of chronic inhalation studies with mainstream cigarette smoke, in hamsters, dogs, and nonhuman primates

Autor: C R, Coggins

Publikováno v: Toxicologic pathology. 29(5)

This paper is the continuation of previously published work, a review limited to studies on rats and mice. This paper makes an identical evaluation as before, but, restricting the species being evaluated to representative studies of smoke-exposed ham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::931e878c51ab3d8152af23a1291b5f2f
https://pubmed.ncbi.nlm.nih.gov/11695572

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No justified use of placebos for pain

Autor: C C, Coggins

Publikováno v: Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing. 32(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f249aec7170dfb3cd90a34d80339bf9
https://pubmed.ncbi.nlm.nih.gov/10887707

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Fourteen-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. II. DNA adducts and alveolar macrophage cytogenetics

Autor: C K, Lee, B G, Brown, B A, Reed, C A, Rahn, C R, Coggins, D J, Doolittle, A W, Hayes

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 19(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6912521384b013b6bc061a4f4233ac17
https://pubmed.ncbi.nlm.nih.gov/1397795

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Fourteen-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. I. Inhalation toxicology and histopathology

Autor: C R, Coggins, P H, Ayres, A T, Mosberg, M W, Ogden, J W, Sagartz, A W, Hayes

Publikováno v: Fundamental and Applied Toxicology

Sprague-Dawley rats were exposed 6 hr per day for 14 consecutive days to aged and diluted sidestream smoke (ADSS), used as a surrogate for Environmental Tobacco Smoke (ETS), at concentrations of 0.1 (typical), 1 (extreme), or 10 (exaggerated) mg of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ee8ac8bbfa3a80183ced4365f133bd6
https://pubmed.ncbi.nlm.nih.gov/1397794

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Design and statistical issues of the Modification of Diet in Renal Disease Trial. The Modification of Diet in Renal Disease Study Group

Autor: G J, Beck, R L, Berg, C H, Coggins, J J, Gassman, L G, Hunsicker, M D, Schluchter, G W, Williams

Publikováno v: Controlled clinical trials. 12(5)

The Modification of Diet in Renal Disease Trial is a multicenter randomized clinical trial for men and women aged 18-70 years with chronic renal disease who are not on dialysis and who have not had a kidney transplant. Study participants are randomiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a002fbadb23afe42ae161a936c1ef3ac
https://pubmed.ncbi.nlm.nih.gov/1664792

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Analysis of cytogenetic effects in bone-marrow cells of rats subchronically exposed to smoke from cigarettes which burn or only heat tobacco

Autor: C K, Lee, B G, Brown, E A, Reed, G D, Lowe, S C, McKarns, C W, Fulp, C R, Coggins, P H, Ayres, D J, Doolittle

Publikováno v: Mutation research. 240(4)

The genotoxic effects of 90-day nose-only exposures to smoke from new cigarettes, which heat but do not burn tobacco (New), or from reference cigarettes, which burn tobacco, were evaluated in Sprague-Dawley rats by examining the cytogenetic endpoints

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dbdbc9bd9d0a66cb4562859a625d393
https://pubmed.ncbi.nlm.nih.gov/2330011

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