Zobrazeno 1 - 10 of 13 pro vyhledávání: '"C A, Walawander"'
1
Implementation of a nursing home urinary incontinence management program with and without tolterodine
Autor: J G, Ouslander, C, Maloney, T H, Grasela, L, Rogers, C A, Walawander
Publikováno v: Journal of the American Medical Directors Association. 2(5)
To evaluate the implementation of a nursing home urinary incontinence management program.A prospective field trial of the program incorporating practice guidelines and principles of continuous quality improvement.Five nursing homes in New York, Virgi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0305f9e5950225d90bf34b4a1de61b7c
https://pubmed.ncbi.nlm.nih.gov/12812542
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2
Symptomatic cardiotoxicity associated with 5-fluorouracil
Autor: C C, Meyer, K A, Calis, L B, Burke, C A, Walawander, T H, Grasela
Publikováno v: Pharmacotherapy. 17(4)
A prospective cohort study was conducted in 35 hospitals with oncology units to determine the incidence of symptomatic cardiotoxicity in patients receiving continuous infusions of 5-fluorouracil (5-FU), and to identify risk factors that could contrib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c2d47e661bd0ac79914ca3490693c7d
https://pubmed.ncbi.nlm.nih.gov/9250550
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3
Sepsis syndrome and associated sequelae in patients at high risk for gram-negative sepsis
Autor: K, Conboy, L S, Welage, C A, Walawander, L C, Duffy, R C, Welliver, M A, Zielezny, J T, DiPiro, M A, Raebel, T H, Grasela
Publikováno v: Pharmacotherapy. 15(1)
We conducted a prospective surveillance study of 80 hospitals across the United States to determine the incidence of sepsis syndrome and its associated sequelae in hospitalized patients over age 18 years who were administered antibiotics for suspecte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d631f7eef87d22e7304ee6aa7917414
https://pubmed.ncbi.nlm.nih.gov/7739948
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4
Effects on recovery when isoflurane is used to supplement propofol-nitrous oxide anesthesia
Autor: P F, White, T H, Stanley, J L, Apfelbaum, T H, Grasela, C C, Hug, C H, McLeskey, M L, Nahrwold, M F, Roizen, R A, Thisted, C A, Walawander
Publikováno v: Anesthesia and analgesia. 77
During propofol-nitrous oxide (N2O) anesthesia, volatile anesthetics are frequently administered to treat signs of inadequate anesthesia and to decrease the possibility of intraoperative awareness. Because the clinical effects of this combination hav
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b022fb7b1126c6899e0fe8d7a03a83fa
https://pubmed.ncbi.nlm.nih.gov/8214692
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5
The initial clinical experience of 1819 physicians in maintaining anesthesia with propofol: characteristics associated with prolonged time to awakening
Autor: J L, Apfelbaum, T H, Grasela, C C, Hug, C H, McLeskey, M L, Nahrwold, M F, Roizen, T H, Stanley, R A, Thisted, C A, Walawander, P F, White
Publikováno v: Anesthesia and analgesia. 77
In October 1989, propofol underwent Phase IV Food and Drug Administration testing that involved 25,981 patients, 1722 institutions, and 1819 anesthesiologists. Participants were 18-80 yr of age and ASA physical status I-III; they could not have a con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::82062a302331aebe3093072baf3d284d
https://pubmed.ncbi.nlm.nih.gov/8214691
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6
Adverse events in a multicenter phase IV study of propofol: evaluation by anesthesiologists and postanesthesia care unit nurses
Autor: C H, McLeskey, C A, Walawander, M L, Nahrwold, M F, Roizen, T H, Stanley, R A, Thisted, P F, White, J L, Apfelbaum, T H, Grasela, C C, Hug
Publikováno v: Anesthesia and analgesia. 77
Phase II and III studies are tightly controlled trials investigating adverse effects before government approval of a new drug. However, because postapproval Phase IV studies involve a much larger and more complex population, the true nature of advers
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc05a431bc4a0e0af737a5a94b339c91
https://pubmed.ncbi.nlm.nih.gov/8214694
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7
The role of pharmacoepidemiology research in postmarketing surveillance and anesthesia practice/critical care medicine
Autor: T H, Grasela, W D, Watkins, C C, Hug, C H, McLeskey, M L, Nahrwold, M F, Roizen, T H, Stanley, R A, Thisted, C A, Walawander, P F, White
Publikováno v: Anesthesia and analgesia. 77
Despite tremendous efforts to ensure the safety and effectiveness of newly marketed medications, a number of these have had significant problems after introduction of the drug to the market. Such problems highlight the practical limitations of clinic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49117a8b2de6765c6ee57d42656128cc
https://pubmed.ncbi.nlm.nih.gov/8214697
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8
How do anesthesiologists select patients when introducing a new drug into practice?
Autor: M F, Roizen, T H, Stanley, R A, Thisted, C A, Walawander, P F, White, J L, Apfelbaum, T H, Grasela, C C, Hug, C H, McLeskey, M L, Nahrwold
Publikováno v: Anesthesia and analgesia. 77
As part of the marketing strategy for the anesthetic drug propofol (Diprivan), Stuart Pharmaceuticals began a Phase IV postmarketing study soon after the drug received Food and Drug Administration approval in 1989. We used data from this study to tes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1079ce51d9d9e0e4f7ea2ef95dfcc245
https://pubmed.ncbi.nlm.nih.gov/8214695
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9
Hemodynamic effects of propofol: data from over 25,000 patients
Autor: C C, Hug, C H, McLeskey, M L, Nahrwold, M F, Roizen, T H, Stanley, R A, Thisted, C A, Walawander, P F, White, J L, Apfelbaum, T H, Grasela
Publikováno v: Anesthesia and analgesia. 77
To investigate clinically important hypotension and bradycardia after induction of anesthesia with propofol, we analyzed data from a Phase IV stepwise study involving 25,981 patients, 1722 institutions, and 1819 anesthesiologists. In Step 1, propofol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d5634e53f572e7b388a8c5e4f149612
https://pubmed.ncbi.nlm.nih.gov/8214693
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10
Phase IV study of propofol: validation of the data set
Autor: M L, Nahrwold, M F, Roizen, T H, Stanley, R A, Thisted, C A, Walawander, P F, White, J L, Apfelbaum, T H, Grasela, C C, Hug, C H, McLeskey
Publikováno v: Anesthesia and analgesia. 77
In 1989-1990, Stuart Pharmaceuticals conducted a Phase IV study of propofol on over 26,000 patients, later making the large data base available to a team of epidemiologists and anesthesiologists for analysis. We now describe the process of verifying
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aca861a02679817b933953c77c85228f
https://pubmed.ncbi.nlm.nih.gov/8214696
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