Zobrazeno 1 - 10
of 21
pro vyhledávání: '"C A, Pinkert"'
Autor:
Charles B. Stephensen, Roberto Cattaneo, Marilyn K. Leung, Claudia Kemper, John P. Atkinson, M K Liszewski, C. A. Pinkert
SUMMARYHuman membrane cofactor protein (MCP; CD46) is a widely distributed complement regulator. In the mouse, expression of MCP is largely restricted to the testis while a related, widely expressed protein (Crry) appears to perform MCP's (CD46) regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6ef945acb28cd8b79af3ec4b0a22d0
https://europepmc.org/articles/PMC1906059/
https://europepmc.org/articles/PMC1906059/
Publikováno v:
Journal of lipid research. 41(12)
Type 1 diabetes mellitus is a devastating disorder affecting both glucose and lipid metabolism. Using the nonobese diabetic (NOD) mouse model, we found that diabetic mice had a liver-specific increase in steady state mRNA levels for enzymes involved
Publikováno v:
Transgenic research. 8(2)
At present, there are no means for creation of relevant animal models of human mitochondrial DNA (mtDNA)-based diseases in a directed fashion. As an initial step towards this end, we have developed a microinjection technique for transfer of isolated,
Publikováno v:
Transgenic research. 6(6)
A method for mitochondria isolation and interspecific transfer of mitochondria was developed in mice. Mitochondria were isolated from Mus spretus liver samples for microinjection into fertilized ova obtained from superovulated M. musculus domesticus
Publikováno v:
Biotechnology (Reading, Mass.). 16
Publikováno v:
Biology of reproduction. 43(4)
Previous experiments revealed that male transgenic mice bearing a cosmid that included the Class II E alpha gene, about 35 kb of 5' flanking DNA, and the cosmid vector sequences were sterile. To ascertain the cause of the sterility, various subfragme
Autor:
C A, Pinkert
Publikováno v:
BioTechniques. 9(1)
Publikováno v:
Journal of reproduction and fertility. Supplement. 40
Recent research clearly shows that fusion genes can be microinjected into a pronucleus of an ovum and integrate into the pig genome. Animals with such fusion genes are called 'transgenic'. The percentage of injected ova that developed into transgenic
Autor:
M, Wieghart, J L, Hoover, M M, McGrane, R W, Hanson, F M, Rottman, S H, Holtzman, T E, Wagner, C A, Pinkert
Publikováno v:
Journal of reproduction and fertility. Supplement. 41
Over the past 5 years, reports detailing the production of transgenic pigs have focussed on enhanced growth performance. Phenotypic side-effects observed in pigs harbouring chimaeric constructs containing metallothionein or Moloney murine leukaemia v
Autor:
C. A. Pinkert
Publikováno v:
Veterinary Pathology. 38:354-354