Zobrazeno 1 - 10
of 36
pro vyhledávání: '"C A, Pegg"'
Autor:
Shoshana D. Brown, Scott C.-H. Pegg, Elaine C. Meng, Conrad C. Huang, Patricia C. Babbitt, Eyal Akiva, Michael A. Hicks, John H. Morris, David Mischel, Gemma L. Holliday, Thomas E. Ferrin
Publikováno v:
Database: The Journal of Biological Databases and Curation
Author(s): Holliday, Gemma L; Brown, Shoshana D; Akiva, Eyal; Mischel, David; Hicks, Michael A; Morris, John H; Huang, Conrad C; Meng, Elaine C; Pegg, Scott C-H; Ferrin, Thomas E; Babbitt, Patricia C | Abstract: With ever-increasing amounts of sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cd0b487bfefeef3dc46a998af762e0
http://europepmc.org/articles/PMC5467548
http://europepmc.org/articles/PMC5467548
Autor:
P. Therese Lang, Natasja Brooijmans, Scott C.-H. Pegg, Demetri T. Moustakas, Eric F. Pettersen, Irwin D. Kuntz, Robert C. Rizzo
Publikováno v:
Journal of Computer-Aided Molecular Design. 20:601-619
We report on the development and validation of a new version of DOCK. The algorithm has been rewritten in a modular format, which allows for easy implementation of new scoring functions, sampling methods and analysis tools. We validated the sampling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6154f47530055b94c6517a7c43f0a872
https://doi.org/10.1007/s10822-006-9060-4
https://doi.org/10.1007/s10822-006-9060-4
Autor:
Patricia J. Chang, Patricia C. Babbitt, Elaine C. Meng, Scott C.-H. Pegg, Jennifer L. Seffernick, Thomas E. Ferrin, John H. Morris, Shoshana D. Brown, Sunil Ojha, Conrad C. Huang
Publikováno v:
Biochemistry. 45:2545-2555
The study of mechanistically diverse enzyme superfamilies-collections of enzymes that perform different overall reactions but share both a common fold and a distinct mechanistic step performed by key conserved residues-helps elucidate the structure-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679d660f4f3e4d1f6a8e481183c2a196
https://doi.org/10.1021/bi052101l
https://doi.org/10.1021/bi052101l
Autor:
Richard J. Jacob, Patricia C. Babbitt, Michael A. Baldwin, Scott C.-H. Pegg, Alma L. Burlingame, Ching C. Wang, Lan Huang
Publikováno v:
Journal of Biological Chemistry. 276:28327-28339
As experimental technologies for characterization of proteomes emerge, bioinformatic analysis of the data becomes essential. Separation and identification technologies currently based on two-dimensional gels/mass spectrometry provide the inherent ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ac41992b44d71d1d4b446d76abccfa
https://doi.org/10.1074/jbc.m008342200
https://doi.org/10.1074/jbc.m008342200
Publikováno v:
Journal of Computer-Aided Molecular Design. 15:911-933
Genetic algorithms have properties which make them attractive in de novo drug design. Like other de novo design programs, genetic algorithms require a method to reduce the enormous search space of possible compounds. Most often this is done using inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b78b0c087d1281db9e432b9c68d58bf
https://doi.org/10.1023/a:1014389729000
https://doi.org/10.1023/a:1014389729000
Autor:
Scott C.-H. Pegg, Patricia C. Babbitt
Publikováno v:
Bioinformatics. 15:729-740
MOTIVATION As genomic sequencing reveals the range of structural classes generated through the evolution of proteins, analysis of the superfamilies to which they belong can contribute important insights for understanding their structure-function rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ba86c6bfdf18d9654633e6416a4aad
https://doi.org/10.1093/bioinformatics/15.9.729
https://doi.org/10.1093/bioinformatics/15.9.729
Autor:
Shoshana D. Brown, Sunil Ojha, Patricia C. Babbitt, Conrad C. Huang, Scott C.-H. Pegg, Thomas E. Ferrin
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6598d5ba566925f5177025171e5225
https://doi.org/10.1096/fasebj.20.5.a899-c
https://doi.org/10.1096/fasebj.20.5.a899-c
Publikováno v:
Virtual Screening in Drug Discovery ISBN: 9780824754792
Virtual Screening in Drug Discovery
Virtual Screening in Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b0837fb5e9f51cfd2705d0fb2afd06
https://doi.org/10.1201/9781420028775.pt5
https://doi.org/10.1201/9781420028775.pt5
Autor:
Scott C H, Pegg, Shoshana, Brown, Sunil, Ojha, Conrad C, Huang, Thomas E, Ferrin, Patricia C, Babbitt
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.
The prediction of protein function from structure or sequence data remains a problem best addressed by leveraging information available from previously determined structure-function relationships. In the case of enzymes, the study of mechanistically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d34c72a41fc1b0e13a7c8b532a781cb8
https://pubmed.ncbi.nlm.nih.gov/15759641
https://pubmed.ncbi.nlm.nih.gov/15759641
Autor:
Patricia C. Babbitt, Scott C.-H. Pegg, Sunil Ojha, Conrad C. Huang, Thomas E. Ferrin, Shoshana D. Brown
Publikováno v:
Pacific Symposium on Biocomputing
The prediction of protein function from structure or sequence data remains a problem best addressed by leveraging information available from previously determined structure-function relationships. In the case of enzymes, the study of mechanistically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::987ece18d7965d707a22121790a840e8
https://doi.org/10.1142/9789812702456_0034
https://doi.org/10.1142/9789812702456_0034