Zobrazeno 1 - 10
of 174
pro vyhledávání: '"C A, Meier"'
Publikováno v:
BMJ Public Health, Vol 2, Iss 2 (2024)
Objective Hypertension and dyslipidaemia are established risk factors for cardiovascular disease (CVD) but they are often insufficient on their own to predict CVD. Inflammation also contributes to CVD, but research on the co-occurrence of inflammatio
Externí odkaz:
https://doaj.org/article/43115fe3a1864167b23d1dd4e5513a5a
Autor:
Gokul Seshadri, Sithara Vivek, Anna Prizment, Eileen M. Crimmins, Eric T. Klopack, Jessica Faul, Weihua Guan, Helen C. S. Meier, Bharat Thyagarajan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAge-related immunosenescence is characterized by changes in immune cell subsets and is associated with mortality. However, since immunosenescence is associated with other concurrent age-related changes such as inflammation and multi-organ
Externí odkaz:
https://doaj.org/article/b537583721734d708c89fbfa9737a968
Autor:
Amanda M. Simanek, Regina Manansala, Jennifer M.P. Woo, Helen C. S. Meier, Belinda L. Needham, Paul L. Auer
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 1976-1990 (2022)
Prenatal socioeconomic disadvantage (SD) has been linked to DNA methylation (DNAm) in adulthood, but whether such epigenetic alterations are present at birth remains unclear. We carried out an epigenome-wide analysis of the association between severa
Externí odkaz:
https://doaj.org/article/54e90af3af614e08b0aeda5db2250af1
Autor:
Ramya Ramasubramanian, Helen C. S. Meier, Sithara Vivek, Eric Klopack, Eileen M. Crimmins, Jessica Faul, Janko Nikolich-Žugich, Bharat Thyagarajan
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background Cellular changes in adaptive immune system accompany the process of aging and contribute to an aging-related immune phenotype (ARIP) characterized by decrease in naïve T-cells (TN) and increase in memory T-cells (TM). A populatio
Externí odkaz:
https://doaj.org/article/951ff79560bb49069c018553c7164c5b
Autor:
Christine G. Parks, Helen C. S. Meier, Todd A. Jusko, Jesse Wilkerson, Frederick W. Miller, Dale P. Sandler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundBetween 1988 and 2012, prevalence of antinuclear antibodies (ANA) increased in the U.S., especially in adolescents and non-Hispanic Whites. Female predominance of ANA suggests a role for hormonal factors, including xenobiotic exposures that
Externí odkaz:
https://doaj.org/article/b4a717a070f14c77a1cdc2957141d849
Autor:
Grace A. Noppert, Lydia Feinstein, Jennifer B. Dowd, Rebecca C. Stebbins, Emma Zang, Belinda L. Needham, Helen C. S. Meier, Amanda Simanek, Allison E. Aiello
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract Background Prior studies in humans have suggested that telomere shortening may be accelerated by infection, but research on multiple pathogens and use of large population-based study samples has been limited. We estimated cross-sectional ass
Externí odkaz:
https://doaj.org/article/d9d6867ed04348d2a042854883068204
Autor:
Helen C. S. Meier, Dale P. Sandler, Jesse Wilkerson, Frederick W. Miller, Gregg E. Dinse, Christine G. Parks
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmunity prevalence, as measured by antinuclear antibodies (ANA), is increasing in U.S. adolescents. Improved hygiene and cleaner environments in childhood may reduce exposure to infections and other immune challenges, resulting in improper immun
Externí odkaz:
https://doaj.org/article/67f864db32af4e95b40f81df9599b284
Autor:
J. A. Judd, J. Canestrari, R. Clark, A. Joseph, P. Lapierre, E. Lasek-Nesselquist, M. Mir, M. Palumbo, C. Smith, M. Stone, A. Upadhyay, S. E. Wirth, R. M. Dedrick, C. G. Meier, D. A. Russell, A. Dills, E. Dove, J. Kester, I. D. Wolf, J. Zhu, E. R. Rubin, S. Fortune, G. F. Hatfull, T. A. Gray, J. T. Wade, K. M. Derbyshire
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Diseases caused by mycobacterial species result in millions of deaths per year globally, and present a substantial health and economic burden, especially in immunocompromised patients. Difficulties inherent in working with mycobacterial pathogens hav
Externí odkaz:
https://doaj.org/article/cede667558a44f6bba3d31d49c998240
Autor:
Emily E Lynch, Helen C S Meier
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234995 (2020)
Environmental conditions that contribute to childhood lead exposure are spatially patterned. Socioeconomic and racial inequities in childhood lead exposure have been well documented, however childhood lead exposure in Milwaukee is understudied. As a
Externí odkaz:
https://doaj.org/article/61ad9c1bec63471b935faa9bd353790d
Autor:
Jennifer M. P. Woo, Amanda Simanek, Katie M. O’Brien, Christine Parks, Symielle Gaston, Paul L. Auer, Rebecca Headley Konkel, Chandra L. Jackson, Helen C. S. Meier, Dale P. Sandler
Publikováno v:
Epidemiology (Cambridge, Mass.). 33(5)
Psychosocial trauma has been hypothesized to influence breast cancer risk, but little is known about how co-occurring traumas-particularly during early life-may impact incidence. We examine the relationship between multiple measures of early-life tra