Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C A, Knupp"'
Autor:
A. Struyvenberg, J. M. Branger, A. van Dijk, A. I. M. Hoepelman, Jan Verhoef, H. Kieft, C. A. Knupp
Publikováno v:
Journal of Antimicrobial Chemotherapy. 32:117-122
We investigated the pharmacokinetics of cefepime after administration of multiple doses to seven patients with the sepsis syndrome. Patients ranged in age from 66 to 78 years (mean +/- S.D.: 74 +/- 5 years); all fulfilled the criteria of the sepsis s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac4f4748368185fd7836372b9ccccf9
https://doi.org/10.1093/jac/32.suppl_b.117
https://doi.org/10.1093/jac/32.suppl_b.117
Publikováno v:
Antiviral Chemistry and Chemotherapy. 2:321-328
The evaluation and development of didanosine as a therapy for HIV-infection has demonstrated that results of cell-culture studies are only approximate predictors of clinical effects. Whereas the antiviral activity of didanosine is achieved in cell cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c196df64e94211a298321381c90254ac
https://doi.org/10.1177/095632029100200601
https://doi.org/10.1177/095632029100200601
Publikováno v:
AIDS research and human retroviruses. 16(5)
The effect of food on didanosine bioavailability and interpatient pharmacokinetic variability was examined in children infected with human immunodeficiency virus type 1 (HIV-1). Didanosine pharmacokinetics were determined during fasting and fed condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cad0bd4824529de7355875761bb0a2b7
https://pubmed.ncbi.nlm.nih.gov/10772527
https://pubmed.ncbi.nlm.nih.gov/10772527
Publikováno v:
Antimicrobial agents and chemotherapy. 41(8)
The pharmacokinetic characteristics of cefepime were determined after first dose (n = 35) and again under steady-state conditions (n = 31) with a group of 37 infants and children. In eight subjects, a cefepime dose given by intramuscular injection wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c3877df77c912c60864084bb48d68f
https://pubmed.ncbi.nlm.nih.gov/9257761
https://pubmed.ncbi.nlm.nih.gov/9257761
Autor:
C A, Knupp, R H, Barbhaiya
Publikováno v:
Biopharmaceuticsdrug disposition. 18(1)
The pharmacokinetics of didanosine and ciprofloxacin were evaluated following the administration of multiple oral doses of each drug as a single agent or in combination. Didanosine was dosed as the Videx chewable/dispersible tablet, which contains th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf7d1efe19b8e21a088b1af933641df9
https://pubmed.ncbi.nlm.nih.gov/9008270
https://pubmed.ncbi.nlm.nih.gov/9008270
Publikováno v:
Biomedical chromatography : BMC. 10(1)
This paper examines the effect of temperature on the chromatographic separation characteristics of anti-HIV agents, didanosine and stavudine. As a result of lowering the column temperature, an improved resolution between didanosine and stavudine peak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3081b8b284ae24a43035ff102cdd2605
https://pubmed.ncbi.nlm.nih.gov/8821868
https://pubmed.ncbi.nlm.nih.gov/8821868
Publikováno v:
Pharmacotherapy. 13(5)
To determine the disposition of cefepime in patients with cystic fibrosis compared with healthy controls.Open-label, single-dose study.Laboratoire de Pharmacocinétique Clinique, Université Laval, Québec, Canada.Twelve patients with the confirmed d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fc6ca674ffb1e91ed0a72de4ce5aac8
https://pubmed.ncbi.nlm.nih.gov/8247913
https://pubmed.ncbi.nlm.nih.gov/8247913
Publikováno v:
Pharmaceutical research. 10(8)
Didanosine is a purine nucleoside analogue approved for the treatment of human immunodeficiency virus infection. It is extremely unstable at pH values less than 3 and requires protection against gastric acid-induced hydrolysis. Beagle dogs pretreated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a44e9d9911c32871a9e1a2e59bcd94d
https://pubmed.ncbi.nlm.nih.gov/8415401
https://pubmed.ncbi.nlm.nih.gov/8415401
Autor:
M P, Okamoto, M A, Gill, R K, Nakahiro, A, Bedikian, A, Chin, A E, Yellin, T V, Berne, C A, Knupp
Publikováno v:
Clinical pharmacy. 12(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e2782ef6fc972313c74d044c613759e
https://pubmed.ncbi.nlm.nih.gov/8453862
https://pubmed.ncbi.nlm.nih.gov/8453862
Autor:
R H, Barbhaiya, C A, Knupp, S T, Forgue, G R, Matzke, C E, Halstenson, J A, Opsahl, K A, Pittman
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 19(1)
The metabolism and disposition of an iv-administered, 1000 mg (100 microCi) single dose of the 14C-labeled cephalosporin cefepime was studied in healthy and renally impaired male volunteers. The 14C-label was located in the methyl group of the N-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f01a357f3b5affb62ac3acec227db52
https://pubmed.ncbi.nlm.nih.gov/1673424
https://pubmed.ncbi.nlm.nih.gov/1673424