Zobrazeno 1 - 10
of 523
pro vyhledávání: '"C A, Hayes"'
Autor:
Grace Naswa Makokha, Huarui Bao, C. Nelson Hayes, Maidina Abuduwaili, Elijah Songok, Makoto Hijikata, Kazuaki Chayama
Publikováno v:
Journal of Epidemiology and Global Health, Vol 14, Iss 3, Pp 677-689 (2024)
Abstract Background Hepatitis C (HCV) is a virus that causes chronic liver disease, end-stage cirrhosis, and liver cancer, yet most infected individuals remain undiagnosed or untreated. Kenya is a country located in Sub-Saharan Africa (SSA) where the
Externí odkaz:
https://doaj.org/article/c50aff9df7f04f68b655711e1ec828f8
Autor:
Masanari Kosaka, Hatsue Fujino, Masataka Tsuge, Shinsuke Uchikawa, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, C. Nelson Hayes, Shiro Oka
Publikováno v:
Livers, Vol 4, Iss 3, Pp 364-376 (2024)
The preS1 region of the large hepatitis B virus (HBV) surface protein is a crucial component in HBV infection; however, its impact on the development of hepatocellular carcinoma (HCC) remains unknown. This study investigated the relationship between
Externí odkaz:
https://doaj.org/article/281f1728ddd34a2eb174c618f49f5d04
Autor:
Yuko Nagaoki, Kenji Yamaoka, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Hiroshi Aikata, C. Nelson Hayes, Masataka Tsuge, Shiro Oka
Publikováno v:
Livers, Vol 4, Iss 3, Pp 352-363 (2024)
To clarify the risk factors for the aggravation of esophagogastric varices (EGVs) after hepatitis C virus (HCV) eradication with direct-acting antiviral (DAA) therapy, we enrolled 167 consecutive patients with HCV-related compensated cirrhosis who ac
Externí odkaz:
https://doaj.org/article/9561c7e746144a2781c2f6ff47ab51b5
Autor:
Akemi Ichikawa, Daiki Miki, C. Nelson Hayes, Yuji Teraoka, Hikaru Nakahara, Chise Tateno, Yuji Ishida, Kazuaki Chayama, Shiro Oka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract We developed a fatty liver mouse model using human hepatocyte chimeric mice. As transplanted human hepatocytes do not respond to mouse growth hormone (GH) and tend to accumulate fat, we hypothesized that addition of human GH would alter lipi
Externí odkaz:
https://doaj.org/article/823f2b970a7e470a9a6466b9c9a9406a
Autor:
Masami Yamauchi, Atsushi Ono, Kei Amioka, Yasutoshi Fujii, Hikaru Nakahara, Yuji Teraoka, Shinsuke Uchikawa, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Wataru Okamoto, Daiki Miki, Tomokazu Kawaoka, Masataka Tsuge, Michio Imamura, C. Nelson Hayes, Waka Ohishi, Takeshi Kishi, Mizuki Kimura, Natsumi Suzuki, Koji Arihiro, Hiroshi Aikata, Kazuaki Chayama, Shiro Oka
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Abstract Background Lenvatinib, a multiple receptor tyrosine kinase inhibitor, might exert antitumor effects via tumor immune modulation. However, changes in the tumor immune microenvironment induced by lenvatinib are poorly understood. We investigat
Externí odkaz:
https://doaj.org/article/ba99e570f9db4c279b4af8e694a6a536
Autor:
Motomitsu Fukuhara, Yuji Urabe, Hikaru Nakahara, Akira Ishikawa, Kazuki Ishibashi, Hirona Konishi, Junichi Mizuno, Hidenori Tanaka, Akiyoshi Tsuboi, Ken Yamashita, Yuichi Hiyama, Hidehiko Takigawa, Takahiro Kotachi, Ryo Yuge, C. Nelson Hayes, Shiro Oka
Publikováno v:
Cancer Medicine, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is sometimes detected in non‐drinker and non‐smoker females who are considered to have very low risk of ESCC development in daily practice. This study examined the clinicopathological
Externí odkaz:
https://doaj.org/article/18112acfe22a49b58f8a1d639ed09a9f
Autor:
Yusuke Johira, Takashi Nakahara, Takahiro Kinami, Shintaro Yamasaki, Masanari Kosaka, Yuki Shirane, Ryoichi Miura, Serami Murakami, Shigeki Yano, Kei Amioka, Kensuke Naruto, Yuwa Ando, Yumi Kosaka, Kenichiro Kodama, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Wataru Okamoto, Masami Yamauchi, Tomokazu Kawaoka, C. Nelson Hayes, Masataka Tsuge, Michio Imamura, Hiroshi Aikata, Shiro Oka
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a new classification system for fatty liver disease. In this study, we investigated the clinical characteristics of patients with MAFLD-hepatocellular carcino
Externí odkaz:
https://doaj.org/article/571494618e314b039648ca2219373de7
Autor:
Yuki Yoshikawa, Michio Imamura, Masami Yamauchi, C. Nelson Hayes, Hiroshi Aikata, Wataru Okamoto, Yoshihiro Miyata, Morihito Okada, Noboru Hattori, Kazuhiko Sugiyama, Yukio Yoshioka, Shigeaki Toratani, Masaaki Takechi, Tatsuo Ichinohe, Tsutomu Ueda, Sachio Takeno, Tsuyoshi Kobayashi, Hideki Ohdan, Jun Teishima, Michihiro Hide, Yasushi Nagata, Yoshiki Kudo, Koji Iida, Kazuaki Chayama
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background While immune checkpoint inhibitors (ICIs) occasionally cause immune-related adverse events (irAEs) in various organs, the prevalence of irAEs and potential risk factors have not been clarified. We identified irAE predictive factor
Externí odkaz:
https://doaj.org/article/9db6981ec3ff4d57acfc8ee546284f44
Autor:
J. V. Sales-Silva, K. Cunha, V. V. Smith, S. Daflon, D. Souto, R. Guerço, A. Queiroz, C. Chiappini, C. R. Hayes, T. Masseron, Sten Hasselquist, D. Horta, N. Prantzos, M. Zoccali, C. Allende Prieto, B. Barbuy, R. Beaton, D. Bizyaev, J. G. Fernández-Trincado, P. M. Frinchaboy, J. A. Holtzman, J. A. Johnson, Henrik Jönsson, S. R. Majewski, D. Minniti, D. L. Nidever, R. P. Schiavon, M. Schultheis, J. Sobeck, G. S. Stringfellow, G. Zasowski
Publikováno v:
The Astrophysical Journal, Vol 965, Iss 2, p 119 (2024)
This study probes the chemical abundances of the neutron-capture elements cerium and neodymium in the inner Milky Way from an analysis of a sample of ∼2000 stars in the Galactic bulge bar spatially contained within ∣ X _Gal ∣ < 5 kpc, ∣ Y _Ga
Externí odkaz:
https://doaj.org/article/bf9f0e7edf9b47579c042e31316ff074
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundChronic Hepatitis B virus (HBV) infection causes liver cirrhosis and cancer and is a major public health concern in Kenya. However, so far no systematic review and meta-analysis has been conducted to estimate the burden of disease in the co
Externí odkaz:
https://doaj.org/article/3d0a13e08ea546458a333c6894abca77