Zobrazeno 1 - 9
of 9
pro vyhledávání: '"C A, Haiman"'
Autor:
S. Lani Park, Sharon E. Murphy, Yesha M. Patel, C A Haiman, Daniel O. Stram, Linda M. Polfus, David Conti, Loïc Le Marchand
Publikováno v:
Cancer Research. 78:232-232
The primary risk factor for lung cancer (second most common cancer in men and women in the U.S.) is tobacco smoking. Prior GWAS have identified variants in the CHRNA5-CHRNA3-CHRNB4 cluster (chr 15q25) to be associated with smoking. Total nicotine equ
Autor:
D J, Hunter, E, Riboli, C A, Haiman, D, Albanes, D, Altshuler, S J, Chanock, R B, Haynes, B E, Henderson, R, Kaaks, D O, Stram, G, Thomas, M J, Thun, H, Blanché, J E, Buring, N P, Burtt, E E, Calle, H, Cann, F, Canzian, Y C, Chen, G A, Colditz, D G, Cox, A M, Dunning, H S, Feigelson, M L, Freedman, J M, Gaziano, E, Giovannucci, S E, Hankinson, J N, Hirschhorn, R N, Hoover, T, Key, L N, Kolonel, P, Kraft, L, Le Marchand, S, Liu, J, Ma, S, Melnick, P, Pharaoh, M C, Pike, C, Rodriguez, V W, Setiawan, M J, Stampfer, E, Trapido, R, Travis, J, Virtamo, S, Wacholder, W C, Willett
Publikováno v:
Nature reviews. Cancer. 5(12)
Most cases of breast and prostate cancer are not associated with mutations in known high-penetrance genes, indicating the involvement of multiple low-penetrance risk alleles. Studies that have attempted to identify these genes have met with limited s
Autor:
F Canzian, Sara Lindstroem, D. Campa, Ruth C. Travis, David J. Hunter, Rudolph Kaaks, Loic Le Marchand, Regina G. Ziegler, C A Haiman
Publikováno v:
European Journal of Cancer. 48:S167-S168
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(7)
The A2 allele of the CYP17 gene has been thought to be associated with increased functional activity of this steroidogenic enzyme. Consequently, the A2 allele has been examined as a biomarker of individual susceptibility to hormone-related diseases a
Autor:
C, Guillemette, I, De Vivo, S E, Hankinson, C A, Haiman, D, Spiegelman, D E, Housman, D J, Hunter
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)
UDP-glucuronosyltransferases (UGTs) catalyze the detoxification and the elimination of a large number of endogenous and exogenous compounds in the liver and extrahepatic tissues. One of the UGT1A family members, UGT1A1, is involved in estradiol metab
Publikováno v:
Cancer research. 61(10)
Among women, the A2 allele of CYP17 has been associated with elevated levels of endogenous steroid hormones; however, it does not seem to be a strong independent risk factor for breast cancer. We assessed the association between the A2 allele of CYP1
Autor:
C A, Haiman, S E, Hankinson, D, Spiegelman, I, De Vivo, G A, Colditz, W C, Willett, F E, Speizer, D J, Hunter
Publikováno v:
International journal of cancer. 87(2)
The CYP19 gene codes for aromatase, a key steroidogenic enzyme involved in the conversion of androgens to estrogens. A tetranucleotide (TTTA) repeat polymorphism is present in intron 4 of CYP19; 2 out of 4 breast cancer case-control studies have repo
Autor:
C A, Haiman, S E, Hankinson, D, Spiegelman, G A, Colditz, W C, Willett, F E, Speizer, K T, Kelsey, D J, Hunter
Publikováno v:
Cancer research. 59(5)
The A2 allele of CYP17 has been associated with polycystic ovarian syndrome, elevated levels of certain steroid hormones in premenopausal women, and increased breast cancer risk. We prospectively assessed the association between the A2 allele of CYP1
Autor:
Chen F; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California., Wan P; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California., R Wilkens L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii., A Haiman C; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California.
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [Cancer Epidemiol Biomarkers Prev] 2022 May 04; Vol. 31 (5), pp. 999-1005.