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pro vyhledávání: '"C A, Ferrendelli"'
Autor:
L T, Potter, L A, Ballesteros, L H, Bichajian, C A, Ferrendelli, A, Fisher, H E, Hanchett, R, Zhang
Publikováno v:
Molecular pharmacology. 39(2)
Binding assays involving various antagonists, including N-[3H] methylscopolamine, [3H]quinuclidinyl benzilate, AFDX-116, pirenzepine, and propylbenzilylcholine mustard, disclosed only a single population of M2 muscarinic receptors in membranes from t
Publikováno v:
Molecular pharmacology. 35(5)
Tetrahydroaminoacridine (THA) and a variety of other nonclassical antagonists of muscarine receptors were studied for their ability to bind to primary and allosteric sites on muscarine receptors in rabbit hippocampal membranes. Competition curves bet
Autor:
L T, Potter, C A, Ferrendelli
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 248(3)
The ability of 16 well-known cholinergic agonists to compete with 1 nM [3H]pirenzepine for the high (KH) and low (KL) affinity states of M1 muscarine receptors was studied, using rabbit hippocampal membranes suspended in 20 mM Tris buffer containing