Zobrazeno 1 - 10 of 12 pro vyhledávání: '"C A, Dangelmaier"'
1
Trifluoperazine enhances accumulation and inhibits phosphohydrolysis of phosphatidate in thrombin-stimulated platelets
Autor: H, Holmsen, C A, Dangelmaier
Publikováno v: Thrombosis and haemostasis. 64(2)
Trifluoperazine (TFP) in concentrations up to 10-15 microM increased the formation of phosphatidic acid (PA) in platelets treated with 0.5 U/ml of thrombin, while higher concentrations of TFP inhibited formation of PA. Liberation of arachidonate (AA)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6887907ccb378d25c876753bb69b8df9
https://pubmed.ncbi.nlm.nih.gov/2125379
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2
Specific correction of impaired acid hydrolase secretion in storage pool-deficient platelets by adenosine diphosphate
Autor: C A Dangelmaier, Holm Holmsen, Harvey J. Weiss, B Lages
Publikováno v: Journal of Clinical Investigation. 81:1865-1872
Storage pool-deficient (SPD) platelets, which have decreased amounts of dense-granule and/or alpha-granule constituents, contain normal amounts of lysosomal acid hydrolases, but in some cases exhibit impaired secretion of these enzymes. We examined t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c73df4046a46844f14b0cd789a2af3a
https://doi.org/10.1172/jci113532
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3
Evidence that the platelet plasma membrane is impermeable to calcium and magnesium complexes of A23187. A23187-induced secretion is inhibited by MG2+ and Ca2+, and requires aggregation and active cyclooxygenase
Autor: C A Dangelmaier, H Holmsen
Publikováno v: Journal of Biological Chemistry. 256:10449-10452
A23187-treated platelets secrete dense granule constituents during centrifugation, an artifact that is presented by prior formalin fixation (Holmsen, H., and Setkowsky-Dangelmaier, C. A. (1977) Biochim. Biophys. Acta 497, 46-61). With this improved a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa52d107382e7c53d2b39de135f2eab7
https://doi.org/10.1016/s0021-9258(19)68641-2
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4
Tight coupling of thrombin-induced acid hydrolase secretion and phosphatidate synthesis to receptor occupancy in human platelets
Autor: S Rongved, C A Dangelmaier, Holm Holmsen
Human platelets incubated with [32P]Pi and [3H]arachidonate were transferred to a Pi-free Tyrode's solution by gel filtration. The labile phosphoryl groups of ATP and ADP as well as Pi in the metabolic pool of these platelets had equal specific radio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31f85326510afd2acd0049d463ee2a3
https://europepmc.org/articles/PMC1144156/
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6
Familial bleeding disorder associated with deficiencies in platelet signal processing and glycoproteins
Autor: H, Holmsen, P N, Walsh, K, Koike, S, Murphy, S, Holme, M M, Johnson, C A, Dangelmaier, J J, Egan, J E, Benzel, G P, Tuszynski
Publikováno v: British journal of haematology. 67(3)
Aggregation responses to low concentrations of ADP, epinephrine, collagen and cationophore A23187 in platelets from two family members with marked bleeding tendencies were virtually absent, whereas shape change with ADP was normal. The contribution t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fac95c2817c00b83bcc0289bf738c01e
https://pubmed.ncbi.nlm.nih.gov/3689696
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7
Evidence that the platelet plasma membrane is impermeable to calcium and magnesium complexes of A23187. A23187-induced secretion is inhibited by MG2+ and Ca2+, and requires aggregation and active cyclooxygenase
Autor: H, Holmsen, C A, Dangelmaier
Publikováno v: The Journal of biological chemistry. 256(20)
A23187-treated platelets secrete dense granule constituents during centrifugation, an artifact that is presented by prior formalin fixation (Holmsen, H., and Setkowsky-Dangelmaier, C. A. (1977) Biochim. Biophys. Acta 497, 46-61). With this improved a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77dcce6e76fc58786fb3ac630dbcc218
https://pubmed.ncbi.nlm.nih.gov/6793580
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9
Secretion, subcellular localization and metabolic status of inorganic pyrophosphate in human platelets. A major constituent of the amine-storing granules
Autor: C A Dangelmaier, Holm Holmsen, J S Bauer, Miriam H. Fukami
The platelet content of PPi is 1.90 +/- mumol/10(11) platelets (S.E.M., n = 19) or about 10.5 nmol/mg of protein, several hundred times that found for rat liver. Some 80% of this PPi is secreted by platelets treated with thrombin with a time course a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647eec911f3a6d1dc93f073cbc1d2700
https://europepmc.org/articles/PMC1162312/
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10
Histamine In Pig Platelet Dense Granules
Autor: Holm Holmsen, G L Pakstis, Miriam H. Fukami, Kamil Ugurbil, C A Dangelmaier
Publikováno v: Oral Presentations.
In the course of high resolution nuclear magnetic resonance (n.m.r.) studies of dense granule storage complexes, an amine with two aromatic protons was observed in a proton n.m.r. spectrum of dense granules isolated from pig platelets. This amine was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41c1109a24e7a7ca04237bcf3021c032
https://doi.org/10.1055/s-0038-1652359
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