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Akademický článek

Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline

Autor: Brenna Norton-Baker, Mackenzie C. R. Denton, Natasha P. Murphy, Benjamin Fram, Samuel Lim, Erika Erickson, Nicholas P. Gauthier, Gregg T. Beckham

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract As genomic databases expand and artificial intelligence tools advance, there is a growing demand for efficient characterization of large numbers of proteins. To this end, here we describe a generalizable pipeline for high-throughput protein

Externí odkaz: https://doaj.org/article/663421856240400c9acd2223616ba2ec

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Akademický článek

A New Database of Giant Impacts over a Wide Range of Masses and with Material Strength: A First Analysis of Outcomes

Autor: Alexandre Emsenhuber, Erik Asphaug, Saverio Cambioni, Travis S. J. Gabriel, Stephen R. Schwartz, Robert E. Melikyan, C. Adeene Denton

Publikováno v: The Planetary Science Journal, Vol 5, Iss 3, p 59 (2024)

In the late stage of terrestrial planet formation, planets are predicted to undergo pairwise collisions known as giant impacts. Here, we present a high-resolution database of giant impacts for differentiated colliding bodies of iron–silicate compos

Externí odkaz: https://doaj.org/article/404513f35ee5479fa55c867e8fcc03c3

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Akademický článek

Astrobiology eXploration at Enceladus (AXE): A New Frontiers Mission Concept Study

Publikováno v: The Planetary Science Journal, Vol 4, Iss 6, p 116 (2023)

The Saturnian moon Enceladus presents a unique opportunity to sample the contents of a subsurface liquid water ocean in situ via the continuous plume formed over its south polar terrain using a multi-flyby mission architecture. Previous analyses of t

Externí odkaz: https://doaj.org/article/b2292a897a5240fa9a61af0a95ebbd0e

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Akademický článek

Classification, categorization and essential items for digital ulcer evaluation in systemic sclerosis: a DeSScipher/European Scleroderma Trials and Research group (EUSTAR) survey

Publikováno v: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-6 (2019)

Abstract Background A consensus on digital ulcer (DU) definition in systemic sclerosis (SSc) has been recently reached (Suliman et al., J Scleroderma Relat Disord 2:115-20, 2017), while for their evaluation, classification and categorisation, it is s

Externí odkaz: https://doaj.org/article/8c4529582f0f4e1a859ac3e248e0660a

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Sputnik Planitia as an Impactor Remnant: An Ancient Mascon in a Frozen Ice Mantle

Autor: Harry Ballantyne, Erik Asphaug, C. Adeene Denton, Alexandre Emsenhuber, Martin Jutzi

Introduction: Sputnik Planitia is a ~1600km-wide basin that dominates the surface of Pluto [1,2]. Observations show this feature to be amongst the deepest on Pluto [2], however its original depth is obscured by a thick layer of N2 ice [3]. Its quasi-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dac630e7f9a48908b8bd282e18305891
https://doi.org/10.5194/epsc2022-1130

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POS0853 EFFECTS OF NINTEDANIB ON CIRCULATING BIOMARKERS IN SUBJECTS WITH SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE (SSc-ILD)

Autor: S. Assassi, M. Kuwana, C. P. Denton, T. Maher, C. Diefenbach, C. Ittrich, M. Gahlemann, O. Distler

Publikováno v: Annals of the Rheumatic Diseases. 81:719-720

BackgroundIn the SENSCIS trial in subjects with SSc-ILD, nintedanib reduced the rate of decline in forced vital capacity (FVC) over 52 weeks by 44% compared with placebo.ObjectivesTo investigate the effects of nintedanib on circulating biomarkers of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d228fb2f0b26e9f39e227eb01031cba7
https://doi.org/10.1136/annrheumdis-2022-eular.988

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