Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C A, Blackledge"'
Publikováno v:
Applied Physics B. 93:183-187
The evanescent fields of whispering-gallery modes of a high-Q dielectric microresonator are locally en- hanced via excitation of the surface plasmon resonances of gold nanorods grown on the microresonator's surface. This results in enhanced coupling
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 32:133-140
Following the administration of 2-, 3- and 4-fluorobenzyl alcohols, the major metabolites detected in urine corresponded to the glycine conjugates of the corresponding benzoic acids. Little, or no, unchanged parent compound was detected in the sample
Publikováno v:
Xenobiotica. 32:605-613
1. The metabolism and excretion of 2,4-, 3,5-ditrifluoromethyl- and pentafluorobenzoic acids were studied in the bile-cannulated rat using (1)H- and (19)F-NMR spectroscopy following intraperitoneal administration at 50 mg kg(-1). 2. Pentafluorobenzoi
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 22:1023-1028
The metabolic fate of [14C]-labelled 2 and 4-chlorobenzoic acids (2- and 4-CBA) has been determined in the rat following intraperitoneal (i.p.) administration at 100 mg/kg to male rats. The major route of elimination for both 2-and 4-CBA was urine wi
Autor:
John C. Lindon, Farida Y. K. Ghauri, Ian D. Wilson, Robert C. Glen, C. R. Beddell, C. A. Blackledge, Jeremy K. Nicholson, B. C. Sweatman
Publikováno v:
Biochemical Pharmacology. 44:1935-1946
An extensive set of computed molecular properties, both steric and electronic, have been calculated using molecular orbital and empirical methods for benzoic acid (1) and a congeneric series of substituted benzoic acids, i.e. 2-, 3- and 4-fluorobenzo
Publikováno v:
Scopus-Elsevier
Gold nanorods are grown on the surfaces of high quality optical microresonators. Measurements show huge enhancement of the coupling of resonator modes to an optical fiber in the range of nanorod surface plasmon frequencies.
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 32(1)
Following the administration of 2-, 3- and 4-fluorobenzyl alcohols, the major metabolites detected in urine corresponded to the glycine conjugates of the corresponding benzoic acids. Little, or no, unchanged parent compound was detected in the sample
Autor:
John C. Lindon, M. E. Bollard, Ian D. Wilson, Elaine Holmes, C. A. Blackledge, Jeremy K. Nicholson
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 26(3)
1. 1H and 19F-nmr spectroscopy was used to investigate quantitatively the urinary excretion of the metabolites of 15 substituted phenols in the rat. The compounds studied were: 2-, 3-, and 4-fluorophenols; 2-, 3-, and 4-trifluoromethylphenol; 2,4-, 2
Autor:
Elaine Holmes, Ian D. Wilson, C. R. Beddell, C. A. Blackledge, Jeremy K. Nicholson, M. E. Bollard, B. C. Sweatman, John C. Lindon
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 25(12)
1. The quantitative urinary excretion of the sulphate and glucuronide metabolites of 15 substituted phenols dosed to rat has been determined using high resolution 19F-nmr spectroscopy. 2. The urinary metabolic fate of each of the compounds was relate
Autor:
F Y, Ghauri, C A, Blackledge, R C, Glen, B C, Sweatman, J C, Lindon, C R, Beddell, I D, Wilson, J K, Nicholson
Publikováno v:
Biochemical pharmacology. 44(10)
An extensive set of computed molecular properties, both steric and electronic, have been calculated using molecular orbital and empirical methods for benzoic acid (1) and a congeneric series of substituted benzoic acids, i.e. 2-, 3- and 4-fluorobenzo