Zobrazeno 1 - 10
of 46
pro vyhledávání: '"C A, Bagnell"'
Publikováno v:
The Analyst. 141:661-668
Cellular migration is the movement of cells, cultured as a monolayer; cellular invasion is similar to migration, but requires the cells to move through a three-dimensional material such as basement membrane extract or a synthetic hydrogel. Migration
Autor:
Victoria J. Madden, Bin Zhou, Sylvia Hiller, Bingruo Wu, Ruriko Grant, Catherine K. Hathaway, John R. Hagaman, Albert S. Chang, Mauricio Rojas, Feng Li, Oliver Smithies, Longquan Xu, Masao Kakoki, Hyung Suk Kim, C. Robert Bagnell
Publikováno v:
Proceedings of the National Academy of Sciences. 112:5141-5146
We have generated low-expressing and high-expressing endothelin-1 genes (L and H) and have bred mice with four levels of expression: L/L, ∼20%; L/+, ∼65%; +/+ (wild type), 100%; and H/+, ∼350%. The hypomorphic L allele can be spatiotemporally s
Publikováno v:
Journal of animal science. 95(5)
Maternal effects on development can program cell fate and dictate offspring phenotype. Such effects do not end at birth, but extend into postnatal life through signals communicated from mother to offspring in first milk (colostrum). Transmission of b
Autor:
Catherine K. Hathaway, Ruriko Grant, Masao Kakoki, J. Charles Jennette, Victoria J. Madden, Hyung Suk Kim, Oliver Smithies, Albert S. Chang, C. Robert Bagnell
Human genome-wide association studies have demonstrated that polymorphisms in the engulfment and cell motility protein 1 gene (ELMO1) are strongly associated with susceptibility to diabetic nephropathy. However, proof of causation is lacking. To test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc9c3277bb350cdc3dda0083bd69aaf
https://europepmc.org/articles/PMC4776516/
https://europepmc.org/articles/PMC4776516/
Autor:
Georgette A. Dent, C. Robert Bagnell, Elizabeth B. Dreesen, Christian Jobin, Evan S. Dellon, Marcus Mühlbauer, R. Brooks Vance, Hans H Herfarth
Publikováno v:
ACG Case Reports Journal
In the absence of overt structural abnormalities, the diagnostic approach to chronic abdominal pain can be challenging. Occupational particulate inhalation causing injury to an organ other than the lung is rare. We report a case of inadvertent glass
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:2247-2254
Background— Thrombin concentration modulates fibrin structure and fibrin structure modulates clot stability; however, the impact of localized, cell surface-driven in situ thrombin generation on fibrin structure and stability has not previously been
Autor:
J. Charles Jennette, Ruriko Grant, Oliver Smithies, Catherine K. Hathaway, Masao Kakoki, Albert S. Chang, Victoria J. Madden, Adil Gasim, Hyung Suk Kim, C. Robert Bagnell
Nephropathy develops in many but not all patients with long-standing type 1 diabetes. Substantial efforts to identify genotypic differences explaining this differential susceptibility have been made, with limited success. Here, we show that the expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fede27bf3f5f771d22b4a038b0dc2ae5
Autor:
Oliver Smithies, Cora Jean S. Edgell, Masao Kakoki, Catherine M. Kizer, Nobuyuki Takahashi, Xianwen Yi, C. Robert Bagnell, J. Charles Jennette, Nobuyo Maeda, Hyung Suk Kim
Publikováno v:
Journal of Clinical Investigation. 116:1302-1309
We have previously reported that genetically increased angiotensin-converting enzyme levels, or absence of the bradykinin B2 receptor, increase kidney damage in diabetic mice. We demonstrate here that this is part of a more general phenomenon - diabe
Autor:
Hongtu Zhu, Yael Shiloh-Malawsky, Hongyu An, Zheng Fan, C. Robert Bagnell, Sandra Elmore, Nizar Chahin, Jiahui Wang, Kathy Wilber, Martin Styner, Mihye Ahn, Weili Lin, Joe N. Kornegay
The goal of this study was to assess whether magnetic resonance imaging (MRI) biomarkers can quantify disease progression in golden retriever muscular dystrophy (GRMD) via a natural history study. The proximal pelvic limbs of ten GRMD and eight norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41cf220553228b3c2ece73861dac8ef
Publikováno v:
Society of Reproduction and Fertility supplement. 62
Structural patterning and functional programming of uterine tissues are mechanistically coupled. These processes ensure anteroposterior differentiation of uterine tissues from adjacent segments of the developing female reproductive tract (FRT) and ra