Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Côme Lepage"'
Autor:
Elodie Martin, Karine Le Malicot, Catherine Guérin-Charbonnel, François Bocquet, Olivier Bouché, Anthony Turpin, Thomas Aparicio, Jean-Louis Legoux, Laetitia Dahan, Julien Taieb, Côme Lepage, Louis-Marie Dourthe, Caroline Pétorin, Vincent Bourgeois, Jean-Luc Raoul, Valérie Seegers
Publikováno v:
Current Oncology, Vol 31, Iss 6, Pp 3513-3528 (2024)
In controlled phase II trials, major prognostic factors need to be well balanced between arms. The main procedures used are SPBR (Stratified Permuted Block Randomization) and minimization. First, we provide a systematic review of the treatment alloca
Externí odkaz:
https://doaj.org/article/1b66cb6abd0345388b47ec4d691cb925
Autor:
Bernadette de Rauglaudre, Guillaume Piessen, Marine Jary, Karine Le Malicot, Antoine Adenis, Thibault Mazard, Xavier Benoît D’Journo, Caroline Petorin, Joelle Buffet-Miny, Thomas Aparicio, Rosine Guimbaud, Véronique Vendrely, Côme Lepage, Laetitia Dahan
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 47, Iss , Pp 100804- (2024)
Background: Radiotherapy combined with fluorouracil (5FU) and cisplatin for locally advanced esophageal cancer is associated with a 20–25% pathologic complete response (pCR) rate. Cetuximab increases the efficacy of radiotherapy in patients with he
Externí odkaz:
https://doaj.org/article/71355d6161ff40c6abccfcab110baea0
Autor:
Jean-Louis Legoux, Roger Faroux, Nicolas Barrière, Karine Le Malicot, David Tougeron, Véronique Lorgis, Véronique Guerin-Meyer, Vincent Bourgeois, David Malka, Thomas Aparicio, Matthieu Baconnier, Valérie Lebrun-Ly, Joëlle Egreteau, Faïza Khemissa Akouz, Magali Terme, Côme Lepage, Valérie Boige
Publikováno v:
Cancers, Vol 16, Iss 8, p 1515 (2024)
Fluropyrimidine monotherapy is an option for some patients with inoperable metastatic colorectal cancer. Unlike bevacizumab, the addition of aflibercept, an antibody acting as an anti-angiogenic agent, has never been evaluated in this context. The ai
Externí odkaz:
https://doaj.org/article/40c4d0c2d4ac4f6f983b13dc163f3d4c
Autor:
Nicolas Kerckhove, David Tougeron, Côme Lepage, Denis Pezet, Karine Le Malicot, Manon Pelkowski, Bruno Pereira, David Balayssac
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The use of oxaliplatin in digestive tract cancers could induce severe peripheral neuropathy (OIPN) decreasing the quality of life of patients and survivors. There is currently, no univocal treatment for these peripheral neuropathi
Externí odkaz:
https://doaj.org/article/dd3569c71cf84763ad46868bf3b49e06
Autor:
Rémi Palmier, Thibault Degand, Serge Aho, Côme Lepage, Olivier Facy, Christophe Michiels, Sylvain Manfredi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Many studies identified colonoscopy quality indicators in order to improve performance and safety. We conducted a colonoscopy improvement study. Our study was designed according to a Plan-Do-Study-Act cycle: first recording of our quality in
Externí odkaz:
https://doaj.org/article/6465bd9f03d04cbba17e09e466255298
Autor:
Adrien Grancher, Ludivine Beaussire, Sylvain Manfredi, Karine Le Malicot, Marie Dutherage, Vincent Verdier, Claire Mulot, Olivier Bouché, Jean-Marc Phelip, Charles-Briac Levaché, Philippe Deguiral, Sophie Coutant, David Sefrioui, Jean-François Emile, Pierre Laurent-Puig, Frédéric Bibeau, Pierre Michel, Nasrin Sarafan-Vasseur, Côme Lepage, Frederic Di Fiore
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Circulating tumor DNA (ctDNA) is reported to be promising in localized colorectal cancer (CRC). The present study aimed to retrospectively evaluate the impact of ctDNA in patients with a resected stage II CRC from the PROGIGE 13 trial with available
Externí odkaz:
https://doaj.org/article/41144a49e2c646378fbff7e5463cb372
Autor:
Baptiste Dumetier, Camille Sauter, Azadeh Hajmirza, Baptiste Pernon, Romain Aucagne, Cyril Fournier, Céline Row, Fabien Guidez, Cédric Rossi, Côme Lepage, Laurent Delva, Mary B. Callanan
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3101 (2022)
The human genome is composed of unique DNA sequences that encode proteins and unique sequence noncoding RNAs that are essential for normal development and cellular differentiation. The human genome also contains over 50% of genome sequences that are
Externí odkaz:
https://doaj.org/article/5f5066cdd580422a80e9bd38946b3162
Autor:
Benjamin Tournier, Romain Aucagne, Caroline Truntzer, Cyril Fournier, François Ghiringhelli, Caroline Chapusot, Laurent Martin, Anne Marie Bouvier, Sylvain Manfredi, Valérie Jooste, Mary B. Callanan, Côme Lepage
Publikováno v:
Cancers, Vol 15, Iss 1, p 158 (2022)
Stage II colon cancer (CC), although diagnosed early, accounts for 16% of CC deaths. Predictors of recurrence risk could mitigate this but are currently lacking. By using a DNA methylation-based clinical screening in real-world (n = 383) and in TCGA-
Externí odkaz:
https://doaj.org/article/117029bf35234e17910c120d07e6021f
Autor:
Valérie Jooste, Leila Bengrine-Lefevre, Sylvain Manfredi, Valérie Quipourt, Pascale Grosclaude, Olivier Facy, Côme Lepage, François Ghiringhelli, Anne-Marie Bouvier
Publikováno v:
Cancers, Vol 14, Iss 7, p 1675 (2022)
Background: Our objective was to describe real-world patterns of care and outcomes in pancreatic cancer. Methods: 912 patients diagnosed with pancreatic cancer from 2014 to 2017 were registered by the population-based cancer registry of Burgundy (Fra
Externí odkaz:
https://doaj.org/article/7a85172d03544e82becfbc2720c0c915
Autor:
Caroline Kientz, Marie-Odile Joly, Laurence Faivre, Alix Clemenson, Sophie Dalac, Côme Lepage, Caroline Chapusot, Caroline Jacquot, Renaud Schiappa, Marine Lebrun
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 15, Iss 1, Pp 1-4 (2017)
Abstract Background The tumor spectrum in the Lynch syndrome is well defined, comprising an increased risk of developing colonic and extracolonic malignancies. Muir-Torre syndrome is a variant with a higher risk of skin disease. Patients have been de
Externí odkaz:
https://doaj.org/article/7d02ade405f34cb29ce637ad88e533e9