Výsledky vyhledávání - "César Teijón"

Paclitaxel-loaded folate-targeted albumin-alginate nanoparticles crosslinked with ethylenediamine. Synthesis and in vitro characterization

Autor: Elena Pérez-Izquierdo, César Teijón, María Dolores Blanco, Ana M. Martínez-Relimpio, Marta Benito, Rosa Olmo

Publikováno v: Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Polymers; Volume 13; Issue 13; Pages: 2083
Polymers, Vol 13, Iss 2083, p 2083 (2021)
Polymers
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria

Entre las diferentes formas de reducir los efectos secundarios de los fármacos antineoplásicos en el tratamiento del cáncer, el uso de nanopartículas ha demostrado buenos resultados debido a la protección del fármaco y la posibilidad de liberar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813cac1cef1bb98653966f705966f858

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Biocompatibility studies of intravenously administered ionic-crosslinked chitosan-BSA nanoparticles as vehicles for antitumour drugs

Autor: Marta Benito, M. Dolores Blanco, Elena Conde Pérez, Nuria Montero, César Teijón, José M. Teijón, Rosa Olmo

In this study, a new alternative of ionic crosslinked nanoparticles (NPs) based on chitosan (C) and bovine serum albumin (A; BSA) was evaluated as drug delivery system for antitumour compounds (doxorubicin hydrochloride as a model). The different res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8394f72d2377cfd21211e5bf5cea09
https://hdl.handle.net/11268/10775

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Bioresponsive nanohydrogels based on HEAA and NIPA for poorly soluble drugs delivery

Autor: José M. Teijón, César Teijón, Ana Martínez, M. Dolores Blanco, Elena Conde Pérez

Publikováno v: International Journal of Pharmaceutics. 470:107-119

Environmentally sensitive hydrogels have gained considerable attention in recent years as one of the most promising drug delivery systems. In the present study, two new formulations of pH and temperature stimuli-responsive nanogels (NGs) based on pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbc8f1107ea206e957954925d00ccc6
https://doi.org/10.1016/j.ijpharm.2014.05.002

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Targeting Tamoxifen to Breast Cancer Xenograft Tumours: Preclinical Efficacy of Folate-Attached Nanoparticles Based on Alginate-Cysteine/Disulphide-Bond-Reduced Albumin

Autor: Enriqueta Muñiz, María Dolores Blanco, César Teijón, I. Iglesias, J.M. Teijón, Ana Martínez

Publikováno v: Pharmaceutical Research. 31:1264-1274

In vivo evaluation of tamoxifen (TMX)-loaded folate-targeted nanoparticles prepared from a mixture of disulphide bond reduced bovine serum albumin (BSA-SH) and alginate-cysteine (ALG-CYS) as targeted delivery systems of TMX to tumour tissues. TMX in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb5c2580627f0ef18424868c69889ea
https://doi.org/10.1007/s11095-013-1247-5

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Synthesis and characterisation of alginate/chitosan nanoparticles as tamoxifen controlled delivery systems

Autor: Rosa Olmo, Ana Martínez, Ana Patricia Fernández, María Dolores Blanco, P. Arana, César Teijón

Publikováno v: Journal of Microencapsulation. 30:398-408

Polysaccharides have shown ideal features for their application in nanomedicine as nanoparticulated systems. Nanoparticles based on mixtures of alginate and chitosan (A/Q-50/50, formed by 50% alginate and 50% chitosan, and A/Q-70/30, formed by 70% al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d917eea4eeece5714daec4fcf23e5682
https://doi.org/10.3109/02652048.2012.746747

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Modulation of Lysozyme Activity by Lead Administered by Different Routes. In Vitro Study and Analysis in Blood, Kidney, and Lung

Autor: César Teijón, Rosa Olmo, Juan Vicente Beneit, Antonio Villarino, M. Dolores Blanco, Enriqueta Muñiz

Publikováno v: Biological Trace Element Research. 149:405-411

Modifications in the enzyme activity of lysozyme, a protein implied in the defence barrier of the organism, can be a good biomarker of alterations in the immune system as a result of exposure to toxic metal, such as lead. The aim of this work was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f28aec85e58e01a53792f609cb795f
https://doi.org/10.1007/s12011-012-9446-1

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Synthesis and in vitro biological evaluation as antitumour drug carriers of folate-targeted N-isopropylacrylamide-based nanohydrogels

Autor: Marta Benito, Elena Conde Pérez, Issa Katime, José M. Teijón, Rosa Olmo, César Teijón, María Dolores Blanco

Publikováno v: Polymer International. 61:1202-1212

Copolymeric nanohydrogels based on N-isopropylacrylamide, N-(pyridin-4-ylmethyl)acrylamide and tert-butyl-2acrylamidoethyl carbamate, synthesized by microemulsion polymerization, were characterized using Fourier transform infrared spectroscopy and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc69172792f6ac7a854b7f38046a0ae1
https://doi.org/10.1002/pi.4200

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Tamoxifen-loaded microspheres based on mixtures of poly(D,L-lactide-co-glycolide) and poly(D,L-lactide) polymers: Effect of polymeric composition on drug release and in vitro antitumoral activity

Autor: María Dolores Blanco, J.M. Teijón, Rafael Lozano, I. Iglesias, A. Fenández, César Teijón, Marta Benito

Publikováno v: Journal of Applied Polymer Science. 124:2987-2998

Mixtures of different bioerosionable polyesters were used to prepare microparticulated tamoxifen delivery systems to achieve anticancer effects in breast malignant cancer cells. Tamoxifen (TMX) was included into microspheres (MS) formulated via spray

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42ba708c538365d294d6908c859eaee9
https://doi.org/10.1002/app.35327

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Study of Response of Thymic and Submaxillary Lymph Node Lymphocytes to Administration of Lead by Different Routes

Autor: Carlos Santiago Romero, María Dolores Blanco, Juan Vicente Beneit, Antonio Villarino, Rosa Olmo, César Teijón, Sandra Guerrero

Publikováno v: Biological Trace Element Research. 135:74-85

A number of studies have reported that heavy metals are not only toxic for the organism but they may modulate immune responses. In the current study, the effect of 4-week administration of 200 ppm of PbAc(2), using different routes of administration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c75a719d492a8ffa0d3d1ac976c3291
https://doi.org/10.1007/s12011-009-8495-6

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Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery

Autor: Sandra Guerrero, José M. Teijón, M. Dolores Blanco, César Teijón, Rosa Olmo

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. :716-726

Copolymeric hydrogels of poly(ethylene glycol) monomethacrylate (PEGMA) (P) have been synthesized for use in drug-delivery. New copolymeric hydrogels were prepared by free radical solution polymerization of PEGMA and monomethyl itaconate (MMI) or mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16737a9ab0a5c41d43701ff7b1635469
https://doi.org/10.1002/jbm.b.31448

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