Expresión de proteínas inducibles por frío en la médula espinal de rata sometida a hipotermia sistémica

Autor: Aníbal José Sarotto, Manuel Rey-Funes, Verónica Berta Dorfman, Daniela Contartese, Ignacio M. Larráyoz, Alfredo Martínez, María Agustina Toscanini, César Fabián Loidl

Publikováno v: Revista de la Asociación Argentina de Ortopedia y Traumatología, Vol 87, Iss 3, Pp 393-403 (2022)

Introducción: La lesión traumática de la médula espinal es la principal causa de discapacidad motora en el mundo, y representa una prioridad para la Organización Mundial de la Salud. Se estudió, a nivel estructural y bioquímico, el efecto de l

Externí odkaz: https://doaj.org/article/f254bc7f7d974b9e9dbc61424aa6af9a

Adenosine A1 receptor: A neuroprotective target in light induced retinal degeneration.

Autor: Manuel Soliño, Ester María López, Manuel Rey-Funes, César Fabián Loidl, Ignacio M Larrayoz, Alfredo Martínez, Elena Girardi, Juan José López-Costa

Publikováno v: PLoS ONE, Vol 13, Iss 6, p e0198838 (2018)

Light induced retinal degeneration (LIRD) is a useful model that resembles human retinal degenerative diseases. The modulation of adenosine A1 receptor is neuroprotective in different models of retinal injury. The aim of this work was to evaluate the

Externí odkaz: https://doaj.org/article/c1f16d207c6c48318a47c965afdcef06

Clostridium perfringens epsilon toxin increases the small intestinal permeability in mice and rats.

Autor: Jorge Goldstein, Winston E Morris, César Fabián Loidl, Carla Tironi-Farinati, Bruce A McClane, Francisco A Uzal, Mariano E Fernandez Miyakawa

Publikováno v: PLoS ONE, Vol 4, Iss 9, p e7065 (2009)

Epsilon toxin is a potent neurotoxin produced by Clostridium perfringens types B and D, an anaerobic bacterium that causes enterotoxaemia in ruminants. In the affected animal, it causes oedema of the lungs and brain by damaging the endothelial cells,

Externí odkaz: https://doaj.org/article/f111e85f349d43a18d28a74011ea9a03

Statistical differences resulting from selection of stable reference genes after hypoxia and hypothermia in the neonatal rat brain

Autor: Martin A. Bruno, Martín Bustelo, César Fabián Loidl, Manuel Rey-Funes, D.L.A. van den Hove, Antonio W. D. Gavilanes, Harry W.M. Steinbusch

Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0233387 (2020)
PLOS ONE, 15(5):0233387. Public Library of Science
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Consejo Nacional de Investigaciones Científicas y Técnicas
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Real-time reverse transcription PCR (qPCR) normalized to an internal reference gene (RG), is a frequently used method for quantifying gene expression changes in neuroscience. Although RG expression is assumed to be constant independent of physiologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d00c2a63559a4acbed2ef7cfd013bd3
https://doaj.org/article/ee6b972b24d34b07a25423a6e8272884

Cold shock proteins are expressed in the retina following exposure to low temperatures

Autor: Federico Rolón, Ignacio M. Larrayoz, César Fabián Loidl, Verónica B Dorfman, Manuel Rey-Funes, Daniela S Contartese, Anibal Sarotto, Alfredo Martínez

Publikováno v: RIUR. Repositorio Institucional de la Universidad de La Rioja
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PLoS ONE, Vol 11, Iss 8, p e0161458 (2016)
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Consejo Nacional de Investigaciones Científicas y Técnicas
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PLoS ONE

Hypothermia has been proposed as a therapeutic intervention for some retinal conditions, including ischemic insults. Cold exposure elevates expression of cold-shock proteins (CSP), including RNA-binding motif protein 3 (RBM3) and cold inducible RNA-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1eb18d631a75efdb5aa2e94e818a0e
https://investigacion.unirioja.es/documentos/5d317f432999521056384acd