Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro

Autor: Raquel Herranz, Julia Oto, Marta Hueso, Emma Plana, Fernando Cana, María Castaño, Lourdes Cordón, David Ramos-Soler, Santiago Bonanad, César D. Vera-Donoso, Manuel Martínez-Sarmiento, Pilar Medina

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundNeutrophils, key players of the immune system, also promote tumor development through the formation of neutrophil extracellular traps (NETs) in a process called NETosis. NETs are extracellular networks of DNA, histones and cytoplasmic and g

Externí odkaz: https://doaj.org/article/04a7329b4efd4574b63ffde6063bef24

A predictive model for prostate cancer incorporating PSA molecular forms and age

Autor: Julia Oto, Álvaro Fernández-Pardo, Pilar Medina, Laura Martos, Manuel Martinez, Montserrat Royo, David Hervás, Silvia Navarro, Mary J. Heeb, Francisco España, César D. Vera-Donoso

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

The diagnostic specificity of prostate specific antigen (PSA) is limited. We aimed to characterize eight anti-PSA monoclonal antibodies (mAbs) to assess the prostate cancer (PCa) diagnostic utility of different PSA molecular forms, total (t) and free

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124f4b1a38963e0588bab53f8a18804b
http://link.springer.com/article/10.1038/s41598-020-58836-4

Sildenafil Citrate Enhances Renal Organogenesis Following Metanephroi Allotransplantation into Non-Immunosuppressed Hosts

Autor: Ximo Garcia-Dominguez, César D. Vera-Donoso, Eric Lopez-Moncholi, Victoria Moreno-Manzano, José S. Vicente, Francisco Marco-Jiménez

Publikováno v: Journal of Clinical Medicine
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
Journal of Clinical Medicine; Volume 11; Issue 11; Pages: 3068
Journal of clinical medicine
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

In order to harness the potential of metanephroi allotransplantation to the generation of a functional kidney graft on demand, we must achieve further growth post-transplantation. Sildenafil citrate (SC) is widely known as a useful inductor of angiog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a4350b0b7d2035b5dfc4e2b3aaf0ba
https://doi.org/10.3390/jcm11113068

The Proportion of Prostate-specific Antigen (PSA) Complexed to α1-Antichymotrypsin Improves the Discrimination between Prostate Cancer and Benign Prostatic Hyperplasia in Men with a Total PSA of 10 to 30 μg/L

Autor: Francisco España, César D. Vera, Silvia Navarro, Jose M Alapont, Amparo Estellés, Justo Aznar, Manuel Martinez, Juan F. Jiménez-Cruz, Montserrat Royo

Publikováno v: Clinical Chemistry. 48:1251-1256

Background: The aim of this study was to assess the diagnostic accuracy of the proportion of prostate-specific antigen (PSA) complexed to α1-antichymotrypsin (PSA-α1ACT:PSA ratio) in the differential diagnosis of prostate cancer (CaP) and benign pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a13556c787709adad04ccff94b89661
https://doi.org/10.1093/clinchem/48.8.1251

Prostate-Specific Antigen and Its Complexes with AlpharAntichymotrypsin in the Plasma of Patients with Prostatic Disease

Autor: Amparo Estellés, Juan F. Jiménez-Cruz, Francisco España, Manuel Martinez, César D. Vera, Jaime Sánchez-Cuenca

Publikováno v: European Urology. 30:512-518

OBJECTIVE To improve the specificity and sensitivity of the prostate-specific-antigen (PSA) assay for the distinction between prostate cancer and benign prostate hyperplasia (BPH). METHODS Two sensitive immunoassays, one that measures free PSA and PS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19303ad11dc2c73426c42cebfef0c184
https://doi.org/10.1159/000474226