Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Céline Weller"'
Autor:
Bianca Dietsch, Céline Weller, Carsten Sticht, Carolina de la Torre, Martin Kramer, Sergij Goerdt, Cyrill Géraud, Sebastian A. Wohlfeil
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Liver metastasis is a poor prognostic factor for treatment of advanced cutaneous melanoma with either immunotherapy or targeted therapies. In this study we focused on NRAS mutated melanoma, a cohort with high unmet clinical need.
Externí odkaz:
https://doaj.org/article/ef731503ce0e4d28b81d40a5d89c4f70
Autor:
Anna Sophia Jauch, Sebastian A. Wohlfeil, Céline Weller, Bianca Dietsch, Verena Häfele, Ana Stojanovic, Maximilian Kittel, Hendrik Nolte, Adelheid Cerwenka, Michael Neumaier, Kai Schledzewski, Carsten Sticht, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding to hyaluronan, LYVE-1 can mediate adhesion of leukocytes and cancer cel
Externí odkaz:
https://doaj.org/article/7e8fd3d8dbfa4f958989dc52cbddebc7
Autor:
Sebastian A. Wohlfeil, Verena Häfele, Bianca Dietsch, Céline Weller, Carsten Sticht, Anna Sophia Jauch, Manuel Winkler, Christian David Schmid, Anna Lena Irkens, Ana Olsavszky, Kai Schledzewski, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Cutaneous melanoma exhibits heterogeneous metastatic patterns and prognosis. In this regard, liver metastasis, which is detected in ~ 10–20% of stage 4 patients, came to the fore of melanoma research, as it recently evolved as d
Externí odkaz:
https://doaj.org/article/01d951e23b144140b8554b9e1c7d0db6
Autor:
Viktor Umansky, Peter Altevogt, Jochen Utikal, Vincenzo Bronte, Carsten Kirschning, Vasyl Nagibin, Qian Sun, Laura Hüser, Zeno Riester, Christopher Groth, Rebekka Weber, Céline Weller, Xiaoying Hu, Viktor Fleming
Tumor cell–derived extracellular vesicles (EV) convert normal myeloid cells into myeloid-derived suppressor cells (MDSC), inhibiting antitumor immune responses. Here, we show that EV from Ret mouse melanoma cells upregulate the expression of progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30134e5df523fa5d595f477cc6671751
https://doi.org/10.1158/0008-5472.c.6511317.v1
https://doi.org/10.1158/0008-5472.c.6511317.v1
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Supplementary Data from Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6fbefb5bd893c63c43ec853b8f0ac9
https://doi.org/10.1158/0008-5472.22430214.v1
https://doi.org/10.1158/0008-5472.22430214.v1
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Despite substantial advances in the treatment of solid cancers, resistance to therapy remains a major obstacle to prolonged progression-free survival. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a high level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda4b98719c7b41db9c381a53b02befb
https://doi.org/10.1158/0008-5472.c.6513567.v1
https://doi.org/10.1158/0008-5472.c.6513567.v1
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Supplementary Figure from Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175e0f6375823c8293a0ca1880258164
https://doi.org/10.1158/0008-5472.22430202.v1
https://doi.org/10.1158/0008-5472.22430202.v1
Autor:
Viktor Umansky, Peter Altevogt, Jochen Utikal, Vincenzo Bronte, Carsten Kirschning, Vasyl Nagibin, Qian Sun, Laura Hüser, Zeno Riester, Christopher Groth, Rebekka Weber, Céline Weller, Xiaoying Hu, Viktor Fleming
Figure S1 shows PD-L1 upregulation induced by EV that is mediated by NF-kB activation; Figure S2 shows an induction of PD-L1 and immunosuppressive capacity of myeloid cells through TLR signaling; Figure S3 presents characterization of EV derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cecab5e60228f0bc40f6e2d39a8b7d
https://doi.org/10.1158/0008-5472.22422705
https://doi.org/10.1158/0008-5472.22422705
Autor:
Marina Roy-Luzarraga, Louise E. Reynolds, Beatriz de Luxán-Delgado, Oscar Maiques, Laura Wisniewski, Emma Newport, Vinothini Rajeeve, Rebecca J.G. Drake, Jesús Gómez-Escudero, Frances M. Richards, Céline Weller, Christof Dormann, Ya-Ming Meng, Peter B. Vermeulen, Dieter Saur, Victoria Sanz-Moreno, Ping-Pui Wong, Cyrill Géraud, Pedro R. Cutillas, Kairbaan Hodivala-Dilke
Publikováno v:
Cancer Research. 82:1909-1925
Despite substantial advances in the treatment of solid cancers, resistance to therapy remains a major obstacle to prolonged progression-free survival. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a high level of