Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Céline Van Themsche"'
Autor:
Marion Ravelojaona, Julie Girouard, Emmanuelle Stella Kana Tsapi, Megan Chambers, Cathy Vaillancourt, Céline Van Themsche, Catherine A. Thornton, Carlos Reyes-Moreno
Publikováno v:
Cells, Vol 13, Iss 3, p 229 (2024)
Interleukin-6 (IL-6) superfamily cytokines play critical roles during human pregnancy by promoting trophoblast differentiation, invasion, and endocrine function, and maintaining embryo immunotolerance and protection. In contrast, the unbalanced activ
Externí odkaz:
https://doaj.org/article/7443a6a9e8424458abf59b57801ebb26
Autor:
Yassine Oufqir, Marion Ravelojaona, Julie Girouard, Carlos Reyes-Moreno, Céline Van Themsche, Cathy Vaillancourt, Christian Carrier, Angham Dallagi, Jovane Hamelin-Morrissette
Publikováno v:
Molecular Immunology. 120:32-42
The pleiotropic cytokine leukemia inhibitory factor (LIF) is a key gestational factor known to establish dynamic cellular and molecular cross talk at the feto-maternal interface. Previously, we described the regulatory role of the LIF-trophoblast-IL1
Autor:
Ernesto D'Orio, Lucie Charpentier, Valerie Boulanger, Julie Girouard, Jovane Hamelin-Morrissette, Denise Belgorosky, Robert Perron, Djamel Ramla, Gervais Bérubé, Céline Van Themsche, Ana María Eiján, Carlos Reyes-Moreno
Publikováno v:
Biochemical pharmacology. 176
Muscle-invasive bladder cancer (MIBC) is an aggressive form of urothelial bladder carcinoma (UBC) with poorer outcomes compared to the non-muscle invasive form (NMIBC). Higher recurrent rates and rapid progression after relapse in UBC is known to be
Autor:
Michael J. Soares, Lyne Lafontaine, Eric Asselin, Parvesh Chaudhry, Céline Van Themsche, Marie-Judith Lafleur
Publikováno v:
Biology of Reproduction. 84:553-559
Implantation of an embryo in the endometrium is a critical step for continuation of pregnancy, and implantation failure is a major cause of infertility. In rats, the implantation process involves invasion of the endometrial epithelial lining by the t
Publikováno v:
Journal of Biological Chemistry. 284:20462-20466
Apoptotic cell death plays a normal role in various physiological processes, and deregulated apoptosis is a hallmark of several diseases, including cancer. Cell fate is dictated by the balance between pro- and antiapoptotic factors. Akt is one of the
Publikováno v:
Endocrinology. 149:3789-3798
Endometrial carcinomas are often chemoresistant. TNFalpha shows potent antitumor activity against various cancers, and if it demonstrates good antitumor activity against endometrial cancer, the cytokine could represent a valuable alternative therapeu
Publikováno v:
Expert Opinion on Therapeutic Targets. 8:473-489
The need to pharmacologically control the proteolytic activity of matrix metalloproteinases (MMPs) has been commonly acknowledged, despite its limited efficacy in clinical trials. Among the reasons that explain this failure is our limited understandi
Autor:
Yves St-Pierre, Edouard F. Potworowski, Tommy Alain, Céline Van Themsche, Anna E. Kossakowska, Stefan J. Urbanski
Publikováno v:
The Journal of Immunology. 173:3605-3611
Matrix metalloproteinase (MMP) 10 (stromelysin-2) is known to degrade various components of the extracellular matrix; however, the signals that regulate its expression and its role in lymphoma growth remain unknown. In the present work, we report the
Autor:
Edouard F. Potworowski, Pierre-Olivier Estève, Yves St-Pierre, Céline Van Themsche, Éric Chicoine, Olivier Robledo
Publikováno v:
Biochemical and Biophysical Research Communications. 297:765-772
Several studies have reported that elevated MMP-9 expression in lymphoma tissues correlated with tumor stage, grade, or prognosis. Because the DNA methylation pattern is critical for gene expression, detailed methylation analysis using genomic bisulf
Publikováno v:
Biochemistry and Cell Biology. 79:1-10
The sensitivity of different phospholipase A2 (PLA2)-active fractions eluted from cation-exchange chromatography to para-bromophenacylbromide (pBPB), Ca2+-EGTA, DTT, heat, and H2SO4indicates that human cultured retinal pigment epithelial (hRPE) cells