Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Céline Robichon"'
Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells
Autor:
Soazig Le Lay, Céline Robichon, Xavier Le Liepvre, Georges Dagher, Pascal Ferre, Isabelle Dugail
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 8, Pp 1499-1507 (2003)
Adipose cells specialized in energy storage, contain large intracellular triglyceride-rich lipid droplets, are enriched with free cholesterol, and express sterol-regulated transcription factors such as liver X receptor (LXR). The recent identificatio
Externí odkaz:
https://doaj.org/article/e93284cf975f40469ff53009cdc7a1e4
Autor:
Nicolas J. Rahier, Mangesh Jiotode, Rahul R. Lavhale, François Sautel, Arun Balakrishnan, Abhijeet S. Kate, Shilpa Amit Verekar, Sunil K. Deshmukh, Yannick Aussagues, Prafull Ranadive, Pradipta Tokdar, Céline Robichon, Arnaud Samson, Bruno Gomes, Samuel Meignan, Christian Bailly, Nicolas Molinier, Christophe Long
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:3712-3721
A screening program aimed at discovering novel anticancer agents based on natural products led to the selection of koningic acid (KA), known as a potent inhibitor of glycolysis. A method was set up to produce this fungal sesquiterpene lactone in larg
Autor:
Marthe Moldes, Fabienne Foufelle, Françoise Lasnier, Catherine Postic, Isabelle Dugail, Jean Girard, Céline Dubuquoy, Anne-Françoise Burnol, Clotilde Langlois, Céline Robichon
Publikováno v:
Journal of Hepatology. 55:145-153
Background & Aims The adiponutrin/PNPLA3 (patatin-like phospholipase domain-containing protein 3) variant I148M has recently emerged as an important marker of human fatty liver disease. In order to understand the role of the adiponutrin/PNPLA3 protei
Publikováno v:
médecine/sciences. 24:841-846
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease associated with insulin resistance, obesity and type 2 diabetes. Excessive accumulation of triglycerides (TG) is a hallmark of NAFLD and therefore, a better understandi
Autor:
Céline Robichon, Isabelle Dugail
Publikováno v:
Biochimie. 89:260-264
Cell sterol supply is subjected to tight negative feedback regulation through the SREBP pathway. Upon cholesterol depletion, SREBP transcription factors become activated by cleavage of a membrane bound precursor form, which stimulates the expression
Autor:
Georges Dagher, Nathalie Donne, Anne-Laure Tondu, Xavier Le Liepvre, Isabelle Dugail, Pascal Ferré, Eric Hajduch, Laurent Yvan-Charvet, Céline Robichon
Publikováno v:
Journal of Biological Chemistry. 280:33536-33540
Scavenger receptor class B, type I (SR-BI) mediates the selective uptake of lipids from high density lipoproteins and is expressed in several types of tissues. However, to date little is known about its role in adipocytes. In this study, we investiga
Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells
Autor:
Céline Robichon, Xavier Le Liepvre, Soazig Le Lay, Isabelle Dugail, Georges Dagher, Pascal Ferré
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 8, Pp 1499-1507 (2003)
Adipose cells specialized in energy storage, contain large intracellular triglyceride-rich lipid droplets, are enriched with free cholesterol, and express sterol-regulated transcription factors such as liver X receptor (LXR). The recent identificatio
Autor:
Arnaud Pillon, Laurence Lamant, Jean-Philippe Annereau, Philippe Rochaix, Nicolas Meyer, Christian Bailly, Bruno Gomes, Aline Stennevin, Céline Robichon, Nicolas Guilbaud, Ignacio Garrido-Stowhas, Karim Bedjeguelal, Anna Kruczynski, Sandrine Pourtau, Jean-Christophe Blanchet
Publikováno v:
Cancer Research. 74:1219-1219
Despite recent advances in the therapy of metastatic melanoma, patients have a poor prognosis and die from their disease, with a 5-year survival rate of less than 20%. Metastatic melanoma remains mainly chemoresistant, therefore novel therapeutic str
Publikováno v:
The FASEB Journal. 24
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protease that acts as a regulator of circulating plasma cholesterol levels by enhancing the endocytosis of the low density lipopr...
Autor:
Hervé Guillou, Pierre-Damien Denechaud, Lawrence Serfaty, Fadila Benhamed, Catherine Postic, Maud Lemoine, Justine Bertrand-Michel, Jacqueline Capeau, Jean Girard, Céline Robichon, Marthe Moldes, Chantal Housset, Vlad Ratziu
Publikováno v:
Journal of Clinical Investigation 6 (122), 2176-94. (2012)
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (6), pp.2176-2194. ⟨10.1172/JCI41636⟩
Journal of Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (6), pp.2176-2194. ⟨10.1172/JCI41636⟩
Journal of Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Nonalcoholic fatty liver disease (NAFLD) is associated with all features of the metabolic syndrome. Although deposition of excess triglycerides within liver cells, a hallmark of NAFLD, is associated with a loss of insulin sensitivity, it is not clear