Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Céline Rabeson"'
Autor:
Pierre-Yves Geant, Emeline Cros-Perrial, Laurent Chaloin, Suzanne Peyrottes, Charles Dumontet, Lars Petter Jordheim, Céline Rabeson
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 157, pp.1051-1055. ⟨10.1016/j.ejmech.2018.08.035⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 157, pp.1051-1055. ⟨10.1016/j.ejmech.2018.08.035⟩
The ecto-5′-nucleotidase CD73 has emerged as an important drug target in oncoimmunology as well as in other diseases. We describe new ADP analogues as CD73 inhibitors based on the replacement of the adenosine moiety, in the reference inhibitor APCP
Autor:
Jean-Pierre Sommadossi, Michel Liuzzi, Samira Benzaria-Prad, Anna Giulia Loi, Jerome Peyronnet, Claire Pierra, Dominique Louis Nestor Ghislain Surleraux, Gwenaëlle Sizun, Gilles Gosselin, Maria Seifer, Chiara Musiu, Eric Badaroux, Céline Rabeson, David Standring
Publikováno v:
Future Medicinal Chemistry. 7:1675-1700
Background: Ribonucleoside analogs possessing a β-methyl substituent at the 2′-position of the d-ribose moiety have been previously discovered to be potent and selective inhibitors of hepatitis C virus (HCV) replication, their triphosphates acting
2'-C-Methyl branched pyrimidine ribonucleoside analogues: potent inhibitors of RNA virus replication
Autor:
Clément Counor, Michel Liuzzi, Dorothée Bardiot, Massimo Mura, Vadim Bichko, Maria Seifer, Svetlana Bergelson, Richard Storer, Erika Cretton-Scott, Tony Bouisset, John Mao, David Standring, Michele Tausek, Jean-Pierre Sommadossi, Chiara Musiu, Edward G. Bridges, Gilles Gosselin, Roberta Loddo, Alessandra Cadeddu, Paolo La Colla, Anna Giulia Loi, Céline Rabeson, Samira Benzaria, Claire Pierra
Publikováno v:
Antiviral chemistrychemotherapy. 18(4)
RNA viruses are the agents of numerous widespread and often severe diseases. Their unique RNA-dependent RNA polymerase (RDRP) is essential for replication and, thus, constitutes a valid target for the development of selective chemotherapeutic agents.