Výsledky vyhledávání - "Céline Héraud"

Akademický článek

Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer’s disease

Autor: Christopher Borcuk, Céline Héraud, Karine Herbeaux, Margot Diringer, Élodie Panzer, Jil Scuto, Shoko Hashimoto, Takaomi C. Saido, Takashi Saito, Romain Goutagny, Demian Battaglia, Chantal Mathis

Publikováno v: Aging Brain, Vol 2, Iss , Pp 100042- (2022)

A critical challenge in current research on Alzheimer’s disease (AD) is to clarify the relationship between network dysfunction and the emergence of subtle memory deficits in itspreclinical stage. The AppNL-F/MAPT double knock-in (dKI) model with h

Externí odkaz: https://doaj.org/article/d50e5fb74c914aceb5b4ad94108f83cf

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Akademický článek

Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice

Autor: Céline Héraud, Doris Goufak, Kunie Ando, Karelle Leroy, Valérie Suain, Zehra Yilmaz, Robert De Decker, Michèle Authelet, Vincent Laporte, Jean-Noël Octave, Jean-Pierre Brion

Publikováno v: Neurobiology of Disease, Vol 62, Iss , Pp 100-112 (2014)

Neurofibrillary degeneration in transgenic models of tauopathies has been observed to be enhanced when these models are crossed with transgenic models developing an Aβ pathology. The mechanisms leading to this enhanced tau pathology are not well und

Externí odkaz: https://doaj.org/article/e8cf032029804e2f8088e277ca9d4e53

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Major role of MT2 receptors in the beneficial effect of melatonin on long-term recognition memory in C57BL/6J male mice

Autor: Céline Héraud, Paul Pévet, Marie-Paule Felder-Schmittbuhl, Stéphanie Dumont-Kientzy, Amandine Zimmermann, Chantal Mathis, Karine Herbeaux, Chloé Morel, Cristiana Pistono

Publikováno v: Hormones and Behavior
Hormones and Behavior, Elsevier, 2021, 136, pp.105076. ⟨10.1016/j.yhbeh.2021.105076⟩

International audience; Melatonin, a major signal of the circadian system, is also involved in brain functions such as learning and memory. Chronic melatonin treatment is known to improve memory performances, but the respective contribution of its ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fff211acada178030d6577bd59aed3
https://hal.archives-ouvertes.fr/hal-03396198/document

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Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer’s disease

Autor: Saido T, Saito T, Scuto J, Hashimoto S, Romain Goutagny, Céline Héraud, Demian Battaglia, Karine Herbeaux, Chantal Mathis, Borcuk C, Diringer M, Panzer É

A critical challenge in current research on AD is to clarify the relationship between early neuropathology and network dysfunction associated to the emergence of subtle memory alterations which announce disease onset. In the present work, the new gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2531811fcf5a98e1be5bce19c029824
https://doi.org/10.1101/2021.04.11.439177

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Major role of MT

Autor: Cristiana, Pistono, Amandine, Zimmermann, Chloé, Morel, Karine, Herbeaux, Céline, Héraud, Stéphanie, Dumont-Kientzy, Paul, Pevet, Marie-Paule, Felder-Schmittbuhl, Chantal, Mathis

Publikováno v: Hormones and behavior. 136

Melatonin, a major signal of the circadian system, is also involved in brain functions such as learning and memory. Chronic melatonin treatment is known to improve memory performances, but the respective contribution of its central receptors, MT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f66f5ecdd35f28dc6943264f78b67f77
https://pubmed.ncbi.nlm.nih.gov/34634697

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Autor: Chantal Mathis, Karine Herbeaux, Ayikoe Guy Mensah-Nyagan, Aurélia Cès, Céline Héraud, Jean-Bastien Bott, Thibaut Burg

Publikováno v: Neurobiology of Aging
Neurobiology of Aging, Elsevier, 2018, 62, pp.120-129. ⟨10.1016/j.neurobiolaging.2017.10.013⟩

International audience; Aging is associated with impaired performance in behavioral pattern separation (PS) tasks based on similarities in object features and in object location. These deficits have been attributed to functional alterations in the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c54c0e0dd0186392bf540469b2d06a
https://linkinghub.elsevier.com/retrieve/pii/S0197458017303524

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APOE -Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input

Autor: Karine Herbeaux, Romain Goutagny, Maxime Sartori, Brigitte Cosquer, Jean-Bastien Bott, Chantal Mathis, Céline Héraud, Julien Aubert

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2016, 36 (40), pp.10472-10486. ⟨10.1523/JNEUROSCI.1174-16.2016⟩

Brain mechanisms compensating for cerebral lesions may mitigate the progression of chronic neurodegenerative disorders such as Alzheimer's disease (AD). Mild cognitive impairment (MCI), which often precedes AD, is characterized by neuronal loss in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68366c55b2314fd7d6f750faf83f00d
https://hal.archives-ouvertes.fr/hal-02166087

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Precocious Alterations of Brain Oscillatory Activity in Alzheimer’s Disease: A Window of Opportunity for Early Diagnosis and Treatment

Autor: Valentine Hamm, Céline Héraud, Chantal Mathis, Jean-Christophe Cassel, Romain Goutagny

Publikováno v: Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Frontiers, 2015, 9, pp.491. ⟨10.3389/fncel.2015.00491⟩
Frontiers in Cellular Neuroscience, Vol 9 (2015)

International audience; Alzheimer's disease (AD) is the most common form of neurodegenerative dementia accounting for 50-80% of all age-related dementia. This pathology is characterized by the progressive and irreversible alteration of cognitive func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf732e71a8396dedb8d8ed0d5444b857

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Neuritogenesis induced by vasoactive intestinal peptide, pituitary adenylate cyclase-activating polypeptide, and peptide histidine methionine in SH-SY5y cells is associated with regulated expression of cytoskeleton mRNAs and proteins

Autor: Sandrine Hilairet, Céline Héraud, Jean-François Leterrier, Corinne Chadéneau, Jean-Marc Muller

Publikováno v: Journal of Neuroscience Research. 75:320-329

Vasoactive intestinal peptide (VIP) and the related peptides pituitary adenylate cyclase-activating polypeptide (PACAP) and peptide histidine methionine (PHM) are known to regulate proliferation and/or differentiation in normal and tumoral cells. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a571dd215e85bb860f4db9c4db5d72
https://doi.org/10.1002/jnr.10866

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Severe neurodegeneration with impaired autophagy mechanism triggered by ostm1 deficiency

Autor: Monica Pata, Manfred W. Kilimann, Jean Vacher, Adam Griffiths, Céline Héraud, Subramanya N.M. Pandruvada

Publikováno v: The Journal of biological chemistry. 289(20)

Loss of Ostm1 leads to the most severe form of osteopetrosis in mice and humans. Because functional rescue of the osteopetrotic defect in these mice extended their lifespan from ∼3 weeks to 6 weeks, this unraveled a second essential role of Ostm1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebb04ab790efbfaed150887ce235f51
https://pubmed.ncbi.nlm.nih.gov/24719316

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