Anxiolytic-Like Effect of a Salmon Phospholipopeptidic Complex Composed of Polyunsaturated Fatty Acids and Bioactive Peptides

Autor: Nabila Belhaj, Frédéric Desor, Céline Gleizes, Frédéric M. Denis, Elmira Arab-Tehrany, Rachid Soulimani, Michel Linder

Publikováno v: Marine Drugs, Vol 11, Iss 11, Pp 4294-4317 (2013)

A phospholipopeptidic complex obtained by the enzymatic hydrolysis of salmon heads in green conditions; exert anxiolytic-like effects in a time and dose-dependent manner, with no affection of locomotor activity. This study focused on the physico-chem

Externí odkaz: https://doaj.org/article/353314d600114f01963e3657b8a1c444

Liraglutide protects Rin-m5f β cells by reducing procoagulant tissue factor activity and apoptosis prompted by microparticles under conditions mimicking Instant Blood-Mediated Inflammatory Reaction

Autor: Florence Toti, Malak Abbas, Laurence Kessler, Céline Gleizes, Andrei Alexandru Constantinescu, Fatiha Zobairi, Houda Bouhadja

Publikováno v: Transplant International. 27:733-740

Instant Blood-Mediated Inflammatory Reaction (IBMIR) occurs at the vicinity of transplanted islets immediately after intraportal infusion and is characterized by cytokine secretion, tissue factor (TF) expression, and s cell loss. Microparticles (MPs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b850e8bc6ef7cfb5515b0647a67898a9
https://doi.org/10.1111/tri.12286

Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells

Autor: Guillaume Kreutter, Céline Gleizes, Andrei Alexandru Constantinescu, Malak Abbas, Valérie B. Schini-Kerth, F. Toti, Laurence Kessler, Mohamad Kassem, Ioan Liviu Mitrea

Publikováno v: Molecular and Cellular Biochemistry
Molecular and Cellular Biochemistry, Springer Verlag, 2016, 418 (1-2), pp.91-102. ⟨10.1007/s11010-016-2736-8⟩
Molecular and Cellular Biochemistry, Springer Verlag, 2016, 418 (1-2), pp.91-102. 〈http://link.springer.com/article/10.1007%2Fs11010-016-2736-8〉. 〈10.1007/s11010-016-2736-8〉

International audience; To examine and compare the mitochondria-related cellular mechanisms by which tacrolimus (TAC) or sirolimus (SIR) immunosuppressive drugs alter the pancreatic exocrine and endocrine beta-cell fate. Human exocrine PANC-1 and rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58321805c61b52c4bd30d99c3fb86aa
https://pubmed.ncbi.nlm.nih.gov/27344165

P174 Les microparticules produites par les monocytes en réponse à un stress infectieux altèrent la fonction de la cellule à insuline dans la mucoviscidose

Autor: Andrei Alexandru Constantinescu, Florence Toti, Céline Gleizes, Fatiha Zobairi, Laurence Kessler

Publikováno v: Diabetes & Metabolism. 40:A69-A70

Introduction Des travaux anterieurs ont demontre l’effet deletere de microparticules (MPs) pancreatiques exocrines sur les cellules a insuline en absence d’expression de CFTR. Le but du present travail etait d’etudier le role des MPs monocytair

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c43d15d826ff0a70a586e137a2ec9c63
https://doi.org/10.1016/s1262-3636(14)72465-6

P2116 Effets des microparticules monocytaires et d’origine pancréatique exocrine sur la fonction et le devenir des cellules à insuline dans le contexte de l’infection du diabète de la mucoviscidose

Autor: Florence Toti, E. Yala, Céline Gleizes, Andrei Alexandru Constantinescu, Laurence Kessler, Fatiha Zobairi

Publikováno v: Diabetes & Metabolism. 39:A95

Introduction Les microparticules (MPs), effecteurs cellulaires, sont des fragments de membrane plasmique emis par les cellules stressees. Elles sont des marqueurs pathogenes de desordres thrombotiques et exposent souvent du facteur tissulaire (FT). L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26aea0bd62d85f0a8a334f44848984b8
https://doi.org/10.1016/s1262-3636(13)72026-3