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pro vyhledávání: '"Céline Dujet"'
Autor:
Christel Valencia, Catherine Llorens-Cortes, Céline Dujet, Pascal Villa, Thomas Roux, Dominique Bonnet, Elodie Dupuis, Marcel Hibert, Eric Trinquet, Jean-François Margathe, Xavier Iturrioz
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.925-931. ⟨10.1002/cmdc.201700106⟩
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.925-931. ⟨10.1002/cmdc.201700106⟩
Analogues of apelin-13 carrying diverse spacers and an ad hoc DY647-derived fluorophore were designed and synthesized by chemoselective acylation of α-hydrazinopeptides. The resulting probes retain very high affinity and efficacy for both the wild-t