Blockade of T cell contact-activation of human monocytes by high-density lipoproteins reveals a new pattern of cytokine and inflammatory genes.

Autor: Lyssia Gruaz, Céline Delucinge-Vivier, Patrick Descombes, Jean-Michel Dayer, Danielle Burger

Publikováno v: PLoS ONE, Vol 5, Iss 2, p e9418 (2010)

BACKGROUND: Cellular contact with stimulated T cells is a potent inducer of cytokine production in human monocytes and is likely to play a substantial part in chronic/sterile inflammatory diseases. High-density lipoproteins (HDL) specifically inhibit

Externí odkaz: https://doaj.org/article/8bfc7b89f21a4c05bcc0821b8ff8c1a0

The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra

Autor: Matthias Christian Vogg, Jaroslav Ferenc, Wanda Christa Buzgariu, Chrystelle Perruchoud, Paul Gerald Layague Sanchez, Leonardo Beccari, Clara Nuninger, Youn Le Cras, Céline Delucinge-Vivier, Panagiotis Papasaikas, Stéphane Vincent, Brigitte Galliot, Charisios D. Tsiairis

Publikováno v: Science Advances. 8

The molecular mechanisms that maintain cellular identities and prevent dedifferentiation or transdifferentiation remain mysterious. However, both processes are transiently used during animal regeneration. Therefore, organisms that regenerate their or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bc411288febaa6c32f074df6fef352
https://doi.org/10.1126/sciadv.abo0694

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

Autor: Andrea Weiss, Connie R. Jimenez, Patrycja Nowak-Sliwinska, Pierre-Yves Dietrich, Alexander A. Henneman, Marloes Zoetemelk, Mylène Docquier, Youssef Daali, Thibaud Koessler, Magdalena Rausch, Céline Delucinge-Vivier, Thomas Alexander Mckee, Axel Andres, Christian Toso, Tatiana V. Petrova, Richard R. de Haas, Simone Ragusa, Sander R. Piersma, George Mourad Ramzy, Arjan W. Griffioen, Valentin Mieville, Laura Rubbia-Brandt, Judy R. van Beijnum

Publikováno v: Molecular Oncology
Molecular oncology, vol. 14, no. 11, pp. 2894-2919
Molecular Oncology (2020)
Zoetemelk, M, Ramzy, G M, Rausch, M, Koessler, T, van Beijnum, J R, Weiss, A, Mieville, V, Piersma, S R, de Haas, R R, Delucinge-Vivier, C L, Andres, A, Toso, C, Henneman, A A, Ragusa, S, Petrova, T V, Docquier, M, McKee, T A, Jimenez, C R, Daali, Y, Griffioen, A W, Rubbia-Brandt, L, Dietrich, P-Y & Nowak-Sliwinska, P 2020, ' Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment ', Molecular oncology, vol. 14, no. 11, pp. 2894-2919 . https://doi.org/10.1002/1878-0261.12797
Molecular oncology, 14(11), 2894-2919. Elsevier
Molecular Oncology, Vol 14, Iss 11, Pp 2894-2919 (2020)

Therapeutically guided multidrug optimization (TGMO) technology, composed of experimental testing and in silico modelling, allowed identification of synergistic and selective low‐dose optimized drug combinations (ODCs) active in multiple colorectal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697c0adf39c6243b6ff93e1d09b7bbfb
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85092087787&origin=inward

Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells

Autor: Adriano Rutz, Magdalena Rausch, Mylène Docquier, Jean-Luc Wolfender, Olivier Dormond, Pierre-Marie Allard, Céline Delucinge-Vivier, Patrycja Nowak-Sliwinska

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6467, p 6467 (2021)
Volume 22
Issue 12
International journal of molecular sciences, vol. 22, no. 12, pp. 6467
International journal of molecular sciences, Vol. 22, No 12 (2021) P. 6467

Resistance in clear cell renal cell carcinoma (ccRCC) against sunitinib is a multifaceted process encompassing numerous molecular aberrations. This induces clinical complications, reducing the treatment success. Understanding these aberrations helps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9ad6bd4ae3b20da15c1fb36d5db766
http://europepmc.org/articles/PMC8235637

Identification of Differential Transcriptional Patterns in Primary and Secondary Hyperparathyroidism

Autor: Céline Delucinge-Vivier, Electron Kebebew, Samira M. Sadowski, Marie-Claude Brulhart-Meynet, Frédéric Triponez, Marc Pusztaszeri, Jonathan Sobel, Claudio De Vito, Volodymyr Petrenko, Charna Dibner, Jacques Philippe, Romano Regazzi

Publikováno v: Journal of Clinical Endocrinology and Metabolism (2018)

Context Hyperparathyroidism is associated with hypercalcemia and the excess of parathyroid hormone secretion; however, the alterations in molecular pattern of functional genes during parathyroid tumorigenesis have not been unraveled. We aimed at esta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e863e9857d98d8fd66bef4045f0cff
https://doi.org/10.1210/jc.2017-02506