Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Céline Delloye‐Bourgeois"'
Autor:
Manon Zala, Boris Lipinski, Clélia Costechareyre, Loraine Jarrosson, Romain Teinturier, Edith Julia, Aurélie Vernay, Jérôme Guitton, Alexandra Traverse-Glehen, Gilles Salles, Sarah Huet, Laurent Genestier, Valérie Castellani, Céline Delloye-Bourgeois, Pierre Sujobert
Publikováno v:
HemaSphere, Vol 7, p e55181bb (2023)
Externí odkaz:
https://doaj.org/article/0820a2cfb8c64b40b51d8aa76d526906
Autor:
Dounia Ben Amar, Karine Thoinet, Benjamin Villalard, Olivier Imbaud, Clélia Costechareyre, Loraine Jarrosson, Florie Reynaud, Julia Novion Ducassou, Yohann Couté, Jean-François Brunet, Valérie Combaret, Nadège Corradini, Céline Delloye-Bourgeois, Valérie Castellani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Neuroblastoma is characterised by cell types that feature mesenchymal like or sympathetic noradrenergic transcriptional profiles. Here, the authors show that exogenous factors secreted by sympathetic ganglion cells modulate these profiles, activating
Externí odkaz:
https://doaj.org/article/00dfa78ec20c46a2b14b69df5042c3dd
Autor:
Loraine Jarrosson, Stéphane Dalle, Clélia Costechareyre, Yaqi Tang, Maxime Grimont, Maud Plaschka, Marjorie Lacourrège, Romain Teinturier, Myrtille Le Bouar, Delphine Maucort‐Boulch, Anaïs Eberhardt, Valérie Castellani, Julie Caramel, Céline Delloye‐Bourgeois
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract Metastatic melanoma patients carrying a BRAFV600 mutation can be treated with a combination of BRAF and MEK inhibitors (BRAFi/MEKi), but innate and acquired resistance invariably occurs. Predicting patient response to targeted therapies is c
Externí odkaz:
https://doaj.org/article/88f6786aba76495aab66ddf7dc1d9c9a
Autor:
Loraine Jarrosson, Clélia Costechareyre, Fanny Gallix, Séverine Ciré, Fabien Gay, Olivier Imbaud, Romain Teinturier, Elisabetta Marangoni, Karine Aguéra, Céline Delloye-Bourgeois, Valérie Castellani
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103423- (2021)
Summary: Lack of preclinical patient-derived xenograft cancer models in which to conduct large-scale molecular studies seriously impairs the development of effective personalized therapies. We report here an in vivo concept consisting of implanting h
Externí odkaz:
https://doaj.org/article/e65639efd1b04677a4ab64cc3627fbe5
Autor:
Hugo Ducuing, Thibault Gardette, Aurora Pignata, Karine Kindbeiter, Muriel Bozon, Olivier Thoumine, Céline Delloye-Bourgeois, Servane Tauszig-Delamasure, Valerie Castellani
Publikováno v:
eLife, Vol 9 (2020)
Spinal commissural axon navigation across the midline in the floor plate requires repulsive forces from local Slit repellents. The long-held view is that Slits push growth cones forward and prevent them from turning back once they became sensitized t
Externí odkaz:
https://doaj.org/article/9dea68b98dc34fea99b7095569b511ca
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
In the developing organism, complex molecular programs orchestrate the generation of cells in adequate numbers, drive them to migrate along the correct pathways towards appropriate territories, eliminate superfluous cells, and induce terminal differe
Externí odkaz:
https://doaj.org/article/58f7511816e54cf4ac2c533c7d8ab7eb
Autor:
Patrick N Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P Steinbach, Karl H Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92311 (2014)
The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a l
Externí odkaz:
https://doaj.org/article/02239f747ee44b2a98086e30e7b0add9
Autor:
Céline Delloye-Bourgeois, Benjamin Gibert, Nicolas Rama, Jean-Guy Delcros, Nicolas Gadot, Jean-Yves Scoazec, Robert Krauss, Agnès Bernet, Patrick Mehlen
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001623 (2013)
The Hedgehog signaling is a determinant pathway for tumor progression. However, while inhibition of the Hedgehog canonical pathway-Patched-Smoothened-Gli-has proved efficient in human tumors with activating mutations in this pathway, recent clinical
Externí odkaz:
https://doaj.org/article/27aa3c5108734fa2b093ad1cb3bb326d
Autor:
Onno Akkermans, Céline Delloye-Bourgeois, Claudia Peregrina, Maria Carrasquero-Ordaz, Maria Kokolaki, Miguel Berbeira-Santana, Matthieu Chavent, Florie Reynaud, Ritu Raj, Jon Agirre, Metin Aksu, Eleanor S. White, Edward Lowe, Dounia Ben Amar, Sofia Zaballa, Jiandong Huo, Irene Pakos, Patrick T.N. McCubbin, Davide Comoletti, Raymond J. Owens, Carol V. Robinson, Valérie Castellani, Daniel del Toro, Elena Seiradake
Neural migration is a critical step during brain development that requires the interactions of cell-surface guidance receptors. Cancer cells often hijack these mechanisms to disseminate. Here, we reveal crystal structures of Uncoordinated-5 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f639c2764fd0c039883a39c5c74777
https://doi.org/10.1016/j.cell.2022.09.025
https://doi.org/10.1016/j.cell.2022.09.025
Autor:
Loraine Jarrosson, Stéphane Dalle, Clélia Costechareyre, Yaqi Tang, Maxime Grimont, Maud Plaschka, Marjorie Lacourrège, Romain Teinturier, Myrtille Le Bouar, Delphine Maucort-Boulch, Anaïs Eberhardt, Valérie Castellani, Julie Caramel, Céline Delloye-Bourgeois
Metastatic melanoma patients carrying a BRAFV600mutation can be treated with BRAF inhibitors (BRAFi), in combination with MEK inhibitors (MEKi), but innate and acquired resistance invariably occurs. Resistance can involve transcriptional- and epigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::723f617e5a0de509a85096178b25c832
https://doi.org/10.1101/2022.10.12.511927
https://doi.org/10.1101/2022.10.12.511927