Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Céline Burcklé"'
Cell shape changes mainly rely on the remodeling of the actin cytoskeleton. Multiciliated cells (MCCs) of the mucociliary epidermis ofXenopus laevisembryos, as they mature, dramatically reshape their apical domain to grow cilia, in coordination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f26653c29374eabf8405b564b0b32a1
https://doi.org/10.1101/2023.01.24.525309
https://doi.org/10.1101/2023.01.24.525309
Autor:
Helori-Mael Gaudé, Rémi Salomon, Christine Vesque, Céline Burcklé, Flora Silbermann, Corinne Antignac, Cécile Jeanpierre, Sophie Saunier, Sylvie Schneider-Maunoury
Publikováno v:
Human Molecular Genetics. 20:2611-2627
Nephronophthisis is a hereditary nephropathy characterized by interstitial fibrosis and cyst formation. It is caused by mutations in NPHP genes encoding the ciliary proteins, nephrocystins. In this paper, we investigate the function of nephrocystin-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fcedc776f975c02fe19926bf3b2d22
https://doi.org/10.1093/hmg/ddr164
https://doi.org/10.1093/hmg/ddr164
Autor:
Friedrich C. Luft, Anette Fiebeler, A.H. Jan Danser, Sandra Feldt, Maren Wellner, Geneviève Nguyen, Aurelie Contrepas, Wendy W. Batenburg, Michael Bader, Ulrike Maschke, Istvan Mazak, Heda Kvakan, Céline Burcklé, Ralf Dechend, Dominik N. Müller
Publikováno v:
Hypertension, 51(3), 682-688. Lippincott Williams & Wilkins
The recently cloned (pro)renin receptor [(P)RR] mediates renin-stimulated cellular effects by activating mitogen-activated protein kinases and promotes nonproteolytic prorenin activation. In vivo, (P)RR is said to be blocked with a peptide consisting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e091dadeb9c146163d67205d5448611
https://doi.org/10.1161/hypertensionaha.107.101444
https://doi.org/10.1161/hypertensionaha.107.101444
Autor:
Ingrid M. Garrelds, Michael Bader, Wendy W. Batenburg, Céline Burcklé, René J.A. de Bruin, A.H. Jan Danser, Dominik N. Müller, Manne Krop, Geneviève Nguyen, René de Vries
Publikováno v:
Journal of Hypertension, 25(12), 2441-2453. Lippincott Williams & Wilkins
OBJECTIVE: Mannose 6-phosphate receptors (M6PR) bind both renin and prorenin, and such binding contributes to renin/prorenin clearance but not to angiotensin generation. Here, we evaluated the kinetics of renin/prorenin binding to the recently discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22fb17dd54e55b40c0b7933f0115ecc
https://pure.eur.nl/en/publications/6c8148e6-7056-4a16-a8c2-bbb11b3cd995
https://pure.eur.nl/en/publications/6c8148e6-7056-4a16-a8c2-bbb11b3cd995
Autor:
Magali Barthélémy-Requin, Dominique Massey-Harroche, Barbara Vacca, André Le Bivic, Céline Burcklé
Publikováno v:
Cell Polarity 1 ISBN: 9783319144627
Epithelial layers have allowed the evolution of metazoans by promoting complex multicellularity and protection from the environment. This essential role for epithelia relies on their ability to build an apical surface facing the outside world and a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d8ba3dfacb65213e194116deac7e82
https://doi.org/10.1007/978-3-319-14463-4_3
https://doi.org/10.1007/978-3-319-14463-4_3
Autor:
Jean-Marie Gasc, Elena Popova, Geneviève Nguyen, Ralph Plehm, A.H. Jan Danser, Jörg Peters, Michael Bader, Dominik N. Müller, Ingrid M. Garrelds, Céline Burcklé
Publikováno v:
Hypertension, 47(3), 552-556. Lippincott Williams & Wilkins
Recently, a receptor for renin was described that may be important for vascular uptake and activation of (pro)renin, thus leading to local generation of angiotensin II. To assess the in vivo relevance of this protein, we generated transgenic rats ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c5eab0406d3e6e31706ce692737d0e
https://hdl.handle.net/1765/70429
https://hdl.handle.net/1765/70429
Autor:
Geneviève Nguyen, Céline Burcklé
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 188:621-629
Our model of the renin-angiotensin system has become increasingly complex with the identification of new components and additional roles for angiotensin peptides and their receptors. A functional (pro)renin receptor has been cloned. It acts as (pro)r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ae9591b1e83487179659236768792d
https://doi.org/10.1016/s0001-4079(19)33752-5
https://doi.org/10.1016/s0001-4079(19)33752-5
Publikováno v:
Current Opinion in Nephrology and Hypertension. 12:51-55
The renin-angiotensin system plays a major role in the control of blood pressure and of salt balance, but it is also involved in physiological and pathological processes, development, inflammation and cardiac hypertrophy. A concept has emerged sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c8edfd5051cd8b20b28bf12f644689
https://doi.org/10.1097/00041552-200301000-00009
https://doi.org/10.1097/00041552-200301000-00009
Autor:
Genevieve, Nguyen, Françoise, Delarue, Céline, Burcklé, Latifa, Bouzhir, Thomas, Giller, Jean-Daniel, Sraer
Publikováno v:
Journal of Clinical Investigation. 109:1417-1427
Renin is an aspartyl protease essential for the control of blood pressure and was long suspected to have cellular receptors. We report the expression cloning of the human renin receptor complementary DNA encoding a 350-amino acid protein with a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d526a49ce60cdc11e9c022a6bb24ffd
https://doi.org/10.1172/jci0214276
https://doi.org/10.1172/jci0214276
Publikováno v:
Journal de la Société de Biologie. 196:281-284
Le role des proteases et des antiproteases dans la progression de l’insuffisance renale chronique a ete bien documente. La plupart des etudes ont concerne la plasmine et les activateurs du plasminogene de la famille des serine-proteases, et les met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb316214d9835b9c053833e069c0e437
https://doi.org/10.1051/jbio/2002196040281
https://doi.org/10.1051/jbio/2002196040281