Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Céline Baldeyron"'
Autor:
Laure Bobyk, François Vianna, Juan S. Martinez, Gaëtan Gruel, Marc Benderitter, Céline Baldeyron
Publikováno v:
Biology, Vol 11, Iss 11, p 1652 (2022)
In addition to representing a significant part of the natural background radiation exposure, α-particles are thought to be a powerful tool for targeted radiotherapy treatments. Understanding the molecular mechanisms of recognition, signaling, and re
Externí odkaz:
https://doaj.org/article/a78db64c5d324d8bae995517b7caf872
Autor:
Virginie Maire, Céline Baldeyron, Marion Richardson, Bruno Tesson, Anne Vincent-Salomon, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne De Koning, Guillem Rigaill, Aurélie Dumont, David Gentien, Emmanuel Barillot, Sergio Roman-Roman, Stéphane Depil, Francisco Cruzalegui, Alain Pierré, Gordon C Tucker, Thierry Dubois
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63712 (2013)
Triple-negative breast cancer (TNBC) represents a subgroup of breast cancers (BC) associated with the most aggressive clinical behavior. No targeted therapy is currently available for the treatment of patients with TNBC. In order to discover potentia
Externí odkaz:
https://doaj.org/article/dcb4815980244faa8e17e979409ecdb7
Autor:
Céline Baldeyron, M. Delbos, I. Sorokine-Durm, Pascale Voisin, Aurélie Vaurijoux, Eric Gregoire, Valerie Durand, Valérie Buard, Laurence Roy, Philippe Voisin, Joan Francesc Barquinero, Cécile Martin-Bodiot
Publikováno v:
International Journal of Radiation Biology
International Journal of Radiation Biology, 2018, 94 (3), pp.248-258. ⟨10.1080/09553002.2018.1427903⟩
International Journal of Radiation Biology, 2018, 94 (3), pp.248-258. ⟨10.1080/09553002.2018.1427903⟩
International audience; Purpose The fluorescent in situ hybridization (FISH) technique, which easily detects reciprocal translocations, is currently used to estimate doses in retrospective biological dosimetry, after suspected accidental overexposure
Autor:
Juliette Dabin, Armelle Corpet, Céline Baldeyron, Salomé Adam, Olivier Renaud, Patrick Lomonte, Odile Chevallier, Geneviève Almouzni, Sophie E. Polo, Olivier Leroy
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2016, 64 (1), pp.65-78. ⟨10.1016/j.molcel.2016.08.019⟩
Molecular Cell, Elsevier, 2016, 64 (1), pp.65-78. ⟨10.1016/j.molcel.2016.08.019⟩
Summary Chromatin integrity is critical for cell function and identity but is challenged by DNA damage. To understand how chromatin architecture and the information that it conveys are preserved or altered following genotoxic stress, we established a
Publikováno v:
Cell Cycle. 14:3389-3395
The role of the tumor suppressor BRCA2 has been shaped over 2 decades thanks to the discovery of its protein and nucleic acid partners, biochemical and structural studies of the protein, and the functional evaluation of germline variants identified i
Autor:
Elie Saliba, Stéphane Koundrioukoff, Gordon C. Tucker, David Gentien, Leanne De Koning, Sergio Roman-Roman, Thierry Dubois, Stéphane Depil, Didier Meseure, Didier Decaudin, André Nicolas, Mengliang Ye, Michelle Debatisse, Guillem Rigaill, Amélie Brisson, Alain Pierré, Francisco Cruzalegui, Bruno Tesson, Céline Baldeyron, Fariba Nemati, Elise Martel
Publikováno v:
Molecular Oncology
Molecular Oncology, Elsevier, 2015, 9 (8), pp.1580-1598. ⟨10.1016/j.molonc.2015.04.010⟩
Molecular Oncology, 2015, 9 (8), pp.1580-1598. ⟨10.1016/j.molonc.2015.04.010⟩
Molecular Oncology, Elsevier, 2015, 9 (8), pp.1580-1598. ⟨10.1016/j.molonc.2015.04.010⟩
Molecular Oncology, 2015, 9 (8), pp.1580-1598. ⟨10.1016/j.molonc.2015.04.010⟩
International audience; Triple-negative breast cancer (TNBC) is the breast cancer subgroup with the most aggressive clinical behavior. Alternatives to conventional chemotherapy are required to improve the survival of TNBC patients. Gene-expression an
Autor:
Dominique Stoppa-Lyonnet, Sabine Pagès-Berhouet, Véronique Mosseri, Isabelle Coupier, Alexandra Rousseau, Dora Papadopoulo, Céline Baldeyron, Virginie Caux-Moncoutier
Publikováno v:
Oncogene. 23:914-919
Germ-line mutations of the BRCA1 and BRCA2 genes, when they lead to a truncated protein, confer a high risk of breast and ovarian cancer. However, the role of BRCA1 missense mutations in cancer predisposition is unclear. Functional assays may be very
Autor:
Boris Kysela, Céline Baldeyron, Penny A. Jeggo, Kostas G. Manolis, Michael R. Lieber, Julianne Smith, Dora Papadopoulo, Enriqueta Riballo, Christel Masson
Publikováno v:
Nucleic Acids Research. 31:2157-2167
A DNA ligase IV (LIG4)‐null human pre‐B cell line and human cell lines with hypomorphic mutations in LIG4 are significantly impaired in the frequency and fidelity of end joining using an in vivo plasmid assay. Analysis of the null line demonstrat
Autor:
Dominique Stoppa-Lyonnet, Dora Papadopoulo, Julianne Smith, Céline Jacquemont, Isabelle De Oliveira, Jean Feunteun, Céline Baldeyron, Sophie Gad, Emilie Jacquemin
Publikováno v:
Oncogene. 21:1401-1410
Heterozygosity for mutations in the BRCA1 gene in humans confers high risk for developing breast cancer, but a biochemical basis for this phenotype has not yet been determined. Evidence has accumulated implicating BRCA1, in the maintenance of genomic
Autor:
Hanny Odijk, Roland Kanaar, Jeroen Essers, Willy M. Baarends, Wiggert A. van Cappellen, Evelyne Wassenaar, Evert-Jan Uringa, Alex Maas, Jan H.J. Hoeijmakers, Céline Baldeyron
Publikováno v:
DNA Repair, 25, 27-40. Elsevier
Accurate DNA double-strand break repair through homologous recombination is essential for preserving genome integrity. Disruption of the gene encoding RAD51, the protein that catalyzes DNA strand exchange during homologous recombination, results in l