Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Céline Amadori"'
Autor:
Céline Amadori, Yme Ubeles van der Velden, Damien Bonnard, Igor Orlov, Nikki van Bel, Erwann Le Rouzic, Laia Miralles, Julie Brias, Francis Chevreuil, Daniele Spehner, Sophie Chasset, Benoit Ledoussal, Luzia Mayr, François Moreau, Felipe García, José Gatell, Alessia Zamborlini, Stéphane Emiliani, Marc Ruff, Bruno P. Klaholz, Christiane Moog, Ben Berkhout, Montserrat Plana, Richard Benarous
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-17 (2017)
Abstract Background HIV-1 Integrase (IN) interacts with the cellular co-factor LEDGF/p75 and tethers the HIV preintegration complex to the host genome enabling integration. Recently a new class of IN inhibitors was described, the IN-LEDGF allosteric
Externí odkaz:
https://doaj.org/article/117a4c221a9c47cda76a3b1cf36e763b
Autor:
Vasiliya Kril, Michael Hons, Celine Amadori, Claire Zimberger, Laurine Couture, Yara Bouery, Julien Burlaud-Gaillard, Andrei Karpov, Denis Ptchelkine, Alexandra L. Thienel, Beate M. Kümmerer, Ambroise Desfosses, Rhian Jones, Philippe Roingeard, Laurent Meertens, Ali Amara, Juan Reguera
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current context of global warming. Efficient alphavirus infection relies on the activity of the non-st
Externí odkaz:
https://doaj.org/article/392f25030b2e4f8f892df5a32b1b2c86
Autor:
Erwann Le Rouzic, Damien Bonnard, Frédéric Le Strat, Claire Batisse, Julien Batisse, Céline Amadori, Sophie Chasset, Stéphane Emiliani, Benoit Ledoussal, Marc Ruff, François Moreau, Richard Benarous
LEDGF/p75 (LEDGF) main cellular cofactor of HIV-1 integrase (IN), acts as tethering factor to target integration of HIV in actively transcribed genes. Recently a class of IN inhibitors based on inhibition of LEDGF-IN interaction has been developed. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c46ee39aebce405fdf8a25d57b6cdf
https://doi.org/10.1101/2023.01.28.523533
https://doi.org/10.1101/2023.01.28.523533
Autor:
François Moreau, Sophie Chasset, Felipe García, Marc Ruff, Ben Berkhout, Erwann Le Rouzic, Danièle Spehner, Benoit Ledoussal, Laia Miralles, Stéphane Emiliani, Francis Chevreuil, Igor Orlov, Alessia Zamborlini, Christiane Moog, Julie Brias, Bruno P. Klaholz, Nikki van Bel, Céline Amadori, José M. Gatell, Damien Bonnard, Luzia Mayr, Yme U. van der Velden, Richard Benarous, Montserrat Plana
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-17 (2017)
Retrovirology
Retrovirology, BioMed Central, 2016, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, BioMed Central, 2017, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, 2017, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, 14(1). BioMed Central
Retrovirology
Retrovirology, BioMed Central, 2016, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, BioMed Central, 2017, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, 2017, 14 (1), pp.50. ⟨10.1186/s12977-017-0373-2⟩
Retrovirology, 14(1). BioMed Central
Background HIV-1 Integrase (IN) interacts with the cellular co-factor LEDGF/p75 and tethers the HIV preintegration complex to the host genome enabling integration. Recently a new class of IN inhibitors was described, the IN-LEDGF allosteric inhibitor
Autor:
Arielle R. Rosenberg, Flora Donati, Patrice Bruscella, Matthieu Lemasson, Tony Durand, Quentin Nevers, Hassan Danso, Céline Amadori, Jean-Michel Pawlotsky, Michele Trabucchi, Cyrille Feray, Abdelhakim Ahmed-Belkacem, Camille Baudesson
The liver-specific micro-RNA-122 (miR-122) is required for the replication of hepatitis C virus (HCV). The direct interaction between miR-122 and the 5’ untranslated region of the HCV genome promotes viral replication and protects HCV RNA from degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425704bd81aceb70a789ebe19c8793d5
https://doi.org/10.1101/654392
https://doi.org/10.1101/654392
Autor:
Benoit Ledoussal, Sophie Chasset, Sylvia Eiler, Richard Benarous, Bruno P. Klaholz, Céline Amadori, Marc Ruff, Ali Saïb, Alessia Zamborlini, Danièle Spehner, Igor Orlov, Julien Barbion, François Moreau, Erwann Le Rouzic, Damien Bonnard, Jean-Michel Bruneau, Stéphane Emiliani, Julie Brias, Francis Chevreuil
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (16), pp.6172-6186. ⟨10.1074/jbc.M117.816793⟩
Journal of Biological Chemistry, 2018, 293 (16), pp.6172-6186. ⟨10.1074/jbc.M117.816793⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (16), pp.6172-6186. ⟨10.1074/jbc.M117.816793⟩
Journal of Biological Chemistry, 2018, 293 (16), pp.6172-6186. ⟨10.1074/jbc.M117.816793⟩
Recently, a new class of HIV-1 integrase (IN) inhibitors with a dual mode of action, called IN-LEDGF/p75 allosteric inhibitors (INLAIs), was described. Designed to interfere with the IN-LEDGF/p75 interaction during viral integration, unexpectedly, th
Autor:
François Moreau, Richard Benarous, Jean-Michel Bruneau, Erwann Le Rouzic, Marc Ruff, Ali Saïb, Julie Brias, Stéphane Emiliani, Frédéric Le Strat, Olivier Delelis, Eric Deprez, Céline Amadori, Roxane Beauvoir, Nicolas Levy, Alessia Zamborlini, Francis Chevreuil, Juliette Nguyen, Sophie Chasset, Sylvia Eiler, Sophie Vomscheid, Benoit Ledoussal, Damien Bonnard
Publikováno v:
Retrovirology; Vol 10
Retrovirology
Retrovirology, BioMed Central, 2013, 10 (1), pp.144. 〈10.1186/1742-4690-10-144〉
Retrovirology, BioMed Central, 2013, 10 (1), pp.144. ⟨10.1186/1742-4690-10-144⟩
Retrovirology, 2013, 10 (1), pp.144. ⟨10.1186/1742-4690-10-144⟩
Retrovirology
Retrovirology, BioMed Central, 2013, 10 (1), pp.144. 〈10.1186/1742-4690-10-144〉
Retrovirology, BioMed Central, 2013, 10 (1), pp.144. ⟨10.1186/1742-4690-10-144⟩
Retrovirology, 2013, 10 (1), pp.144. ⟨10.1186/1742-4690-10-144⟩
Background LEDGF/p75 (LEDGF) is the main cellular cofactor of HIV-1 integrase (IN). It acts as a tethering factor for IN, and targets the integration of HIV in actively transcribed gene regions of chromatin. A recently developed class of IN allosteri