Výsledky vyhledávání - "Céline, Vallot"

Akademický článek

A benchmark of computational pipelines for single-cell histone modification data

Autor: Félix Raimundo, Pacôme Prompsy, Jean-Philippe Vert, Céline Vallot

Publikováno v: Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)

Abstract Background Single-cell histone post translational modification (scHPTM) assays such as scCUT&Tag or scChIP-seq allow single-cell mapping of diverse epigenomic landscapes within complex tissues and are likely to unlock our understanding of va

Externí odkaz: https://doaj.org/article/64523a4efefb4a9ea2073d45e702d51d

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Akademický článek

Multi-modal quantification of pathway activity with MAYA

Autor: Yuna Landais, Céline Vallot

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)

Pathways can be activated through various signaling cascades depending on cell type. Here, the authors introduce MAYA, a computational method that can detect and score multiple modes of activation for each pathway, improving the granularity of pathwa

Externí odkaz: https://doaj.org/article/2fa27db0f6fb48f59fc7aabae9ba8962

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Akademický článek

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Autor: Jing Liu, Daniela Ottaviani, Meriem Sefta, Céline Desbrousses, Elodie Chapeaublanc, Rosario Aschero, Nanor Sirab, Fabiana Lubieniecki, Gabriela Lamas, Laurie Tonon, Catherine Dehainault, Clément Hua, Paul Fréneaux, Sacha Reichman, Narjesse Karboul, Anne Biton, Liliana Mirabal-Ortega, Magalie Larcher, Céline Brulard, Sandrine Arrufat, André Nicolas, Nabila Elarouci, Tatiana Popova, Fariba Némati, Didier Decaudin, David Gentien, Sylvain Baulande, Odette Mariani, Florent Dufour, Sylvain Guibert, Céline Vallot, Livia Lumbroso-Le Rouic, Alexandre Matet, Laurence Desjardins, Guillem Pascual-Pasto, Mariona Suñol, Jaume Catala-Mora, Genoveva Correa Llano, Jérôme Couturier, Emmanuel Barillot, Paula Schaiquevich, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Lisa Golmard, Claude Houdayer, Hervé Brisse, Isabelle Bernard-Pierrot, Eric Letouzé, Alain Viari, Simon Saule, Xavier Sastre-Garau, François Doz, Angel M. Carcaboso, Nathalie Cassoux, Celio Pouponnot, Olivier Goureau, Guillermo Chantada, Aurélien de Reyniès, Isabelle Aerts, François Radvanyi

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)

Retinoblastoma is the most frequent intraocular paediatric malignancy whose molecular basis remains poorly understood. Here, the authors perform multi-omic analysis and identify two subtypes; one in a cone differentiated state and one more aggressive

Externí odkaz: https://doaj.org/article/92fda6743ce64715a5b5d4c807ca5ced

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Akademický článek

Interactive analysis of single-cell epigenomic landscapes with ChromSCape

Autor: Pacôme Prompsy, Pia Kirchmeier, Justine Marsolier, Marc Deloger, Nicolas Servant, Céline Vallot

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

Bulk approaches fail to capture the cell-to-cell heterogeneity of chromatin landscapes, while single-cell approaches provide low coverage datasets. Here, the authors present ChromSCape, a user-friendly interactive application that processes single-ce

Externí odkaz: https://doaj.org/article/0b906fb8cdfb44efb7ca71d60a8115fd

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