Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Céline, Rouget"'
Publikováno v:
International Neurourology Journal, Vol 21, Iss 1, Pp 20-28 (2017)
Purpose The aim of this study was to assess the potential involvement of a specific subtype of 5-hydroxytryptamine (5-HT), 5HT2 receptors in neurally-induced contractions of the human detrusor. Methods Contractile responses to electrical field stimul
Externí odkaz:
https://doaj.org/article/8f6d7100966c450d9ce7e6bb872dd5c7
Autor:
Nancy Osorio, Magalie Martineau, Marina Fortea, Céline Rouget, Virginie Penalba, Cindy J. Lee, Werend Boesmans, Malvyne Rolli-Derkinderen, Amit V. Patel, Grégoire Mondielli, Sandrine Conrod, Vivien Labat-Gest, Amandine Papin, Jumpei Sasabe, Jonathan V. Sweedler, Pieter Vanden Berghe, Patrick Delmas, Jean-Pierre Mothet
Publikováno v:
bioRxiv
The enteric nervous system (ENS) is a complex network of diverse molecularly defined classes of neurons embedded in the gastrointestinal wall and responsible for controlling the major functions of the gut. As in the central nervous system, the vast a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0addf97805f1d50903c455cc5372f95b
https://doi.org/10.1101/2023.04.19.537136
https://doi.org/10.1101/2023.04.19.537136
Autor:
Arhamatoulaye Maïga, Jon Merlin, Elodie Marcon, Céline Rouget, Maud Larregola, Bernard Gilquin, Carole Fruchart-Gaillard, Evelyne Lajeunesse, Charles Marchetti, Alain Lorphelin, Laurent Bellanger, Roger J Summers, Dana S Hutchinson, Bronwyn A Evans, Denis Servent, Nicolas Gilles
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68841 (2013)
ρ-Da1a is a three-finger fold toxin from green mamba venom that is highly selective for the α1A-adrenoceptor. This toxin has atypical pharmacological properties, including incomplete inhibition of (3)H-prazosin or (125)I-HEAT binding and insurmount
Externí odkaz:
https://doaj.org/article/ea1b5de2a53b4c798bdec40a54b07f16
Autor:
Pat Brady, Naveena Madhyastha, Ravi Kanth Bhamidipati, Zainuddin Mohd, Dave Downie, Matthew J. Cato, Hong Lin, Céline Rouget, Tania Bakshi, Khuram W. Chaudhary, Dwight M. Morrow, Brian Donovan, Yasuji Matsuoka, Mark A. Seefeld, Kishore Pasikanti, Sridharan Rajagopal, Joerg Holenz, Wei Zhen, Robert W. Dougherty, Mark L. Chapman, Swapan Kumar Samanta, Tingting Fu, Philippe Lluel, Bharathi Mohan Kuppusamy, Guy A. Higgins
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:3793-3797
Neuronal voltage-gated potassium channels, KV7s, are the molecular mediators of the M current and regulate membrane excitability in the central and peripheral neuronal systems. Herein, we report novel small molecule KV7 openers that demonstrate anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfef453d358d286fe6210e7d6cffeb3f
https://doi.org/10.1016/j.bmcl.2018.09.036
https://doi.org/10.1016/j.bmcl.2018.09.036
Publikováno v:
International Neurourology Journal, Vol 21, Iss 1, Pp 20-28 (2017)
International Neurourology Journal
International Neurourology Journal
Purpose The aim of this study was to assess the potential involvement of a specific subtype of 5-hydroxytryptamine (5-HT), 5HT2 receptors in neurally-induced contractions of the human detrusor. Methods Contractile responses to electrical field stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187ccbb4097704265bb1641781617cb7
http://www.einj.org/upload/pdf/inj-1732758-379.pdf
http://www.einj.org/upload/pdf/inj-1732758-379.pdf
Autor:
Mark A, Seefeld, Hong, Lin, Joerg, Holenz, Dave, Downie, Brian, Donovan, Tingting, Fu, Kishore, Pasikanti, Wei, Zhen, Matthew, Cato, Khuram W, Chaudhary, Pat, Brady, Tania, Bakshi, Dwight, Morrow, Sridharan, Rajagopal, Swapan Kumar, Samanta, Naveena, Madhyastha, Bharathi Mohan, Kuppusamy, Robert W, Dougherty, Ravi, Bhamidipati, Zainuddin, Mohd, Guy A, Higgins, Mark, Chapman, Céline, Rouget, Philippe, Lluel, Yasuji, Matsuoka
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(23-24)
Neuronal voltage-gated potassium channels, K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::609cf8993f56f2b66c5f5493e7a4527f
https://pubmed.ncbi.nlm.nih.gov/30327146
https://pubmed.ncbi.nlm.nih.gov/30327146
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 388:727-735
Prostaglandin E2 (PGE2) is well known to modulate urinary bladder functions, but it is also thought to be involved in the pathophysiology of lower urinary tract dysfunctions, since high levels of PGE2 have been found in overactive bladder (OAB) patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55d1d22b431c2999327d2c611b3d77e
https://doi.org/10.1007/s00210-015-1139-9
https://doi.org/10.1007/s00210-015-1139-9
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 388:709-718
In the resting and un-stimulated state, the bladder wall is not quiescent and discrete contractile events, microcontractions, can be recorded in almost all species. This activity contributes to the active element of compliance and to the basal restin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c802244186c0d504219595ca46f4d442
https://doi.org/10.1007/s00210-015-1131-4
https://doi.org/10.1007/s00210-015-1131-4
Autor:
Philippe Lluel, M. Guerard, P Camparo, Moez Rekik, V. Guilloteau, Céline Rouget, Nicolas Gilles, H Botto, Pascal Rischmann, Stefano Palea, Arhamatoulaye Maïga
Publikováno v:
British Journal of Pharmacology. 168:618-631
BACKGROUND AND PURPOSE ρ-Da1a, a 65 amino-acid peptide, has subnanomolar affinity and high selectivity for the human α(1) (A) -adrenoceptor subtype. The purpose of this study was to characterize the pharmacological effects of ρ-Da1a on prostatic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb34df628331e7253439cd8da7847c1
https://doi.org/10.1111/j.1476-5381.2012.02231.x
https://doi.org/10.1111/j.1476-5381.2012.02231.x
Autor:
Timothy D. Westfall, Céline Rouget, Pascal Rischmann, Stefano Palea, Philippe Lluel, Philippe Camparo, Moez Rekik, Henri Botto
Publikováno v:
European Journal of Pharmacology. 690:202-206
Fenoterol has been reported to be a potent and selective β2-adrenoceptor agonist and is currently used clinically to treat asthma. Electrical field stimulation (EFS) of isolated urinary bladder mimics the voiding contraction by stimulating parasympa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55206245590df23345de3c670cd76ffb
https://doi.org/10.1016/j.ejphar.2012.06.036
https://doi.org/10.1016/j.ejphar.2012.06.036