Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Célia Fernandes"'
Autor:
Ana S. André, Joana N. R. Dias, Sandra I. Aguiar, Ana Leonardo, Sara Nogueira, Joana D. Amaral, Célia Fernandes, Lurdes Gano, João D. G. Correia, Marco Cavaco, Vera Neves, Jorge Correia, Miguel Castanho, Cecília M. P. Rodrigues, Maria Manuela Gaspar, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionCancer is a major public health problem with over 19 million cases reported in 2020. Similarly to humans, dogs are also largely affected by cancer, with non-Hodgkin's lymphoma (NHL) among the most common cancers in both species. Comparati
Externí odkaz:
https://doaj.org/article/e1ae62f371ba4be582f085b5e995f720
Autor:
Jacinta O. Pinho, Mariana Matias, Vanda Marques, Carla Eleutério, Célia Fernandes, Lurdes Gano, Joana D. Amaral, Eduarda Mendes, Maria Jesus Perry, João Nuno Moreira, Gert Storm, Ana Paula Francisco, Cecília M.P. Rodrigues, M. Manuela Gaspar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114021- (2023)
The aggressiveness of melanoma and lack of effective therapies incite the discovery of novel strategies. Recently, a new dual acting hybrid molecule (HM), combining a triazene and a ʟ-tyrosine analogue, was synthesized. HM was designed to specifical
Externí odkaz:
https://doaj.org/article/8bcb887236f344f381f68daa3c7e19f5
Autor:
Joana F. Santos, Raquel Azevedo, Miguel Prudêncio, Fernanda Marques, Yann Le Gal, Dominique Lorcy, Célia Fernandes
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 1030 (2023)
Block copolymer micelles (BCMs) can be used to improve the solubility of lipophilic drugs and increase their circulation half-life. Hence, BCMs assembled from MePEG-b-PCL were evaluated as drug delivery systems of gold(III) bis(dithiolene) complexes
Externí odkaz:
https://doaj.org/article/3a9351bda6964a289cc1d420fa4bcb4f
Autor:
Andreia Sousa, Joana F. Santos, Francisco Silva, Sílvia A. Sousa, Jorge H. Leitão, António P. Matos, Teresa Pinheiro, Rafaela A. L. Silva, Dulce Belo, Manuel Almeida, Fernanda Marques, Célia Fernandes
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 564 (2023)
Gold(III) bisdithiolate complexes have been reported as potential antimicrobial and antitumoral agents. The complex [Au(cdc)2]− (cdc=cyanodithioimido carbonate) displayed antimicrobial and outstanding antitumor activity against the ovarian cancer c
Externí odkaz:
https://doaj.org/article/1c04959aeb9c47f8b2f7ab4ee32b1046
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Background Recently, a new family of 99mTc(I)-tricarbonyl complexes bearing an acridine orange (AO) DNA targeting unit and different linkers between the Auger emitter (99mTc) and the AO moiety was evaluated for Auger therapy. Among them, 99m
Externí odkaz:
https://doaj.org/article/5680275189514e088a79bc5cebe60e27
Autor:
Alice D’Onofrio, Francisco Silva, Lurdes Gano, Paula Raposinho, Célia Fernandes, Arkadiusz Sikora, Monika Wyczółkowska, Renata Mikołajczak, Piotr Garnuszek, António Paulo
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2569 (2022)
Several gastrin-releasing peptide receptor (GRPR) antagonists with improved in vivo behavior have been recently developed and tested in the clinic. However, despite the generally mild side effects of peptide receptor radionuclide therapy (PRRT), toxi
Externí odkaz:
https://doaj.org/article/be3a8061859940269765896c9e48ff68
Autor:
Célia Fernandes, Elisa Palma, Francisco Silva, Ana Belchior, Catarina I. G. Pinto, Joana F. Guerreiro, Hugo M. Botelho, Filipa Mendes, Paula Raposinho, António Paulo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7238 (2022)
Although 99mTc is not an ideal Auger electron (AE) emitter for Targeted Radionuclide Therapy (TRT) due to its relatively low Auger electron yield, it can be considered a readily available “model” radionuclide useful to validate the design of new
Externí odkaz:
https://doaj.org/article/aa7fbeed660f4a59a2a048a27598af64
Autor:
Diogo Figueiredo, Célia Fernandes, Francisco Silva, Elisa Palma, Paula Raposinho, Ana Belchior, Pedro Vaz, António Paulo
Publikováno v:
Molecules, Vol 26, Iss 2, p 441 (2021)
For effective Auger therapy of cancer, the Auger-electron emitters must be delivered to the tumor cells in close proximity to a radiosensitive cellular target. Nuclear DNA is considered the most relevant target of Auger electrons to have augmented ra
Externí odkaz:
https://doaj.org/article/f7bff5e5207f44f1b10a0680c2e9fbc6
Autor:
Maisa Cordeiro, Célia Fernandes
Publikováno v:
Anuário de Literatura, Vol 21, Iss 2 (2016)
Este artigo analisa a obra A invenção de Hugo Cabret, de Brian Selznick (2007), ambientada na Paris de 1930. O objetivo deste estudo é verificar o diálogo verbo-visual na obra, catalogada como juvenil e integrante do acervo de 2013 do Programa Na
Externí odkaz:
https://doaj.org/article/c79c9c2b28ee4faf8fb10824d34f3682