Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Célia, Fourrier"'
Autor:
Julien Bensalem, Leonie K. Heilbronn, Jemima R. Gore, Amy T. Hutchison, Timothy J. Sargeant, Célia Fourrier
Publikováno v:
BMC Nutrition, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Background Autophagy is a cellular process that cleanses cells and is particularly important during ageing. Autophagy has been extensively studied in vitro and in animal models and is known to be sensitive to nutrition. However, human data a
Externí odkaz:
https://doaj.org/article/5dcfed50bf8f4395a29d5a0c0c2c2a08
Autor:
Lauren S. Whyte, Célia Fourrier, Sofia Hassiotis, Adeline A. Lau, Paul J. Trim, Leanne K. Hein, Kathryn J. Hattersley, Julien Bensalem, John J. Hopwood, Kim M. Hemsley, Timothy J. Sargeant
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 131-141 (2022)
Lysosomal network abnormalities are an increasingly recognised feature of Alzheimer’s disease (AD), which appear early and are progressive in nature. Sandhoff disease and Tay-Sachs disease (neurological lysosomal storage diseases caused by mutation
Externí odkaz:
https://doaj.org/article/d1d4403666e2493b96517b7138797dcc
Publikováno v:
FEBS Open Bio, Vol 12, Iss 4, Pp 739-757 (2022)
Age‐related diseases represent some of the largest unmet clinical needs of our time. While treatment of specific disease‐related signs has had some success (for example, the effect of statin drugs on slowing progression of atherosclerosis), slowi
Externí odkaz:
https://doaj.org/article/3641831789a243cb958247775f9c99ce
Autor:
Andrew P. Shoubridge, Célia Fourrier, Jocelyn M. Choo, Christopher G. Proud, Timothy J. Sargeant, Geraint B. Rogers
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The gut microbiome-brain axis exerts considerable influence on the development and regulation of the central nervous system. Numerous pathways have been identified by which the gut microbiome communicates with the brain, falling largely into the two
Externí odkaz:
https://doaj.org/article/54c47483657447609ee8b13056af83ef
Autor:
Timothy J. Sargeant, Célia Fourrier
Publikováno v:
Brain, Behavior, and Immunity. 107:98-109
In the last few decades, mounting evidence has highlighted that microglia have crucial roles in both health and disease. This has led to a growing interest in studying human microglia in disease-relevant models. However, current models present limita
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background In patients with major depressive disorder (MDD), antidepressant response and remission rates are low, highlighting the need for new treatment approaches. Recently, the abundant literature linking inflammatory processes and depres
Externí odkaz:
https://doaj.org/article/75c3744462314b47a48f606bb9c68241
Autor:
Célia Fourrier, Julie Remus-Borel, Andrew D. Greenhalgh, Michel Guichardant, Nathalie Bernoud-Hubac, Michel Lagarde, Corinne Joffre, Sophie Layé
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-13 (2017)
Abstract Background Neuroinflammatory processes are considered a double-edged sword, having both protective and detrimental effects in the brain. Microglia, the brain’s resident innate immune cells, are a key component of neuroinflammatory response
Externí odkaz:
https://doaj.org/article/5954c06b94c6461f870f56d3ab9187d5
Autor:
Natalie T. Mills, Hikaru Hori, Scott R. Clark, Célia Fourrier, Bernhard T. Baune, Jennie Louise, K Oliver Schubert, Emma Sampson
Publikováno v:
European Neuropsychopharmacology. 53:34-46
Given the role of low-grade inflammation in the pathophysiology of major depressive disorder (MDD), anti-inflammatory strategies may improve treatment outcomes in some patients. However, it is controversial whether they can be used as adjunctive trea
Publikováno v:
International Journal of Neuropsychopharmacology
Background Partial response to antidepressant medication as well as relapse and treatment resistance are common in major depressive disorder (MDD). Therefore, for most patients with MDD, there will be a need to consider changing antidepressant medica
Autor:
Bernhard T. Baune, Emma Sampson, Jennie Louise, Hikaru Hori, K. Oliver Schubert, Scott R. Clark, Natalie T. Mills, Célia Fourrier
Publikováno v:
European Neuropsychopharmacology. 64:61-62